[Long-Term Survival in a Patient with Stage Ⅳ Gastric Cancer Successfully Treated with Multidisplinary Treatment].


Journal

Gan to kagaku ryoho. Cancer & chemotherapy
ISSN: 0385-0684
Titre abrégé: Gan To Kagaku Ryoho
Pays: Japan
ID NLM: 7810034

Informations de publication

Date de publication:
Apr 2020
Historique:
entrez: 12 5 2020
pubmed: 12 5 2020
medline: 25 7 2020
Statut: ppublish

Résumé

A man in his 60s who had epigastric pain was referred to our hospital and diagnosed with advanced type 3 gastric cancer with multiple liver metastases, cT4acN2cN1(H1), cStage Ⅳ(HER2 3+). He underwent chemotherapy using capecitabine, cisplatin(CDDP), and trastuzumab(T-mab)(XPT). After 7 courses of XPT and 23 courses of XT, liver metastases disappeared, and we decided to perform open distal gastrectomy, D2+ #18 lymphadenectomy, and Billroth Ⅰ reconstruction as a conversion surgery. Despite adjuvant chemotherapy with S-1 plus T-mab, multiple lymph nodes recurrence occurred 3 months after the surgery. He was found to be in complete remission as assessed by CT after 5 courses of second-line CPT-11 treatment, which was discontinued after 17 courses. The patient is alive without recurrence at 57 months after the initial treatment and 22 months after the last treatment.

Identifiants

pubmed: 32389974

Substances chimiques

Trastuzumab P188ANX8CK
Cisplatin Q20Q21Q62J

Types de publication

Case Reports Journal Article

Langues

jpn

Sous-ensembles de citation

IM

Pagination

655-657

Auteurs

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Classifications MeSH