Catalog of exogenous risk factors for bladder carcinogenesis.


Journal

Current opinion in urology
ISSN: 1473-6586
Titre abrégé: Curr Opin Urol
Pays: United States
ID NLM: 9200621

Informations de publication

Date de publication:
05 2020
Historique:
entrez: 3 4 2020
pubmed: 3 4 2020
medline: 15 12 2020
Statut: ppublish

Résumé

The aim of this article is to provide an overview of recent findings regarding the risk factors for bladder cancer. Most of the available data derive from retrospective analysis. Smoking represents the most common and important risk factor. Occupational, dietary, and environmental exogenic carcinogen exposure, as well as several lifestyle factors, can increase the risk of developing bladder cancer. Bladder cancer is a common malignancy worldwide. Cigarette smoking, exposure to aromatic amines and arsenic are known risk factors for bladder cancer. Evidence on other modifiable risk factors such as carcinogen exposure derived from the diet or environment as well as occupational hazards is still weak. Medical conditions leading to chronic inflammation, altering insulin resistance, negatively modulating the immune system and/or genetic alterations may have a role in bladder cancer carcinogenesis. Further studies are, however, necessary to identify possible exogenic risk factors, as well as their interactions, that partake in the carcinogenesis of bladder cancer.

Identifiants

pubmed: 32235283
doi: 10.1097/MOU.0000000000000753
pii: 00042307-202005000-00026
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

449-456

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Auteurs

Victoria Jahrreiss (V)

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Benjamin Pradere (B)

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Department of Urology, CHRU Tours, François Rabelais University, Tours, France.

Ekaterina Laukhtina (E)

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.

Keiichiro Mori (K)

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.

Shahrokh F Shariat (SF)

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Department of Urology, Weill Cornell Medical College, New York, New York, USA.
Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria.
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.
Department of Urology, University of Jordan, Amman, Jordan.
European Association of Urology research foundation, Arnhem, Netherlands.

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