The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection.
Journal
Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R
Informations de publication
Date de publication:
15 12 2019
15 12 2019
Historique:
received:
15
07
2019
accepted:
27
09
2019
pubmed:
5
11
2019
medline:
27
5
2020
entrez:
3
11
2019
Statut:
ppublish
Résumé
Innate lymphoid cells (ILCs) are critical for host defense and tissue repair but can also contribute to chronic inflammatory diseases. The transcription factor RORα is required for ILC2 development but is also highly expressed by other ILC subsets where its function remains poorly defined. We previously reported that
Identifiants
pubmed: 31676672
pii: jimmunol.1900781
doi: 10.4049/jimmunol.1900781
doi:
Substances chimiques
Biomarkers
0
Nuclear Receptor Subfamily 1, Group F, Member 1
0
Rora protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3209-3215Subventions
Organisme : CIHR
ID : PJT-148681
Pays : Canada
Organisme : CIHR
ID : PJT-156235
Pays : Canada
Informations de copyright
Copyright © 2019 by The American Association of Immunologists, Inc.