Multiple roles for HIV broadly neutralizing antibodies.

AIDS Vaccines / immunology Broadly Neutralizing Antibodies / administration & dosage Clinical Trials as Topic HIV Antibodies / immunology HIV Infections / drug therapy Humans Immunization

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
30 10 2019
Historique:
received: 16 09 2019
accepted: 11 10 2019
entrez: 1 11 2019
pubmed: 2 11 2019
medline: 5 9 2020
Statut: ppublish

Résumé

Potent broadly neutralizing antibodies may be used to treat or prevent HIV and to help guide HIV vaccine design.

Identifiants

DOI: 10.1126/scitranslmed.aaz2686 PMID: 31666399 PMC: PMC7171597
pubmed: 31666399
pii: 11/516/eaaz2686
doi: 10.1126/scitranslmed.aaz2686
pmc: PMC7171597
mid: NIHMS1577790
pii:
doi:

Substances chimiques

AIDS Vaccines 0
Broadly Neutralizing Antibodies 0
HIV Antibodies 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : UM1 AI144371
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI144462
Pays : United States

Informations de copyright

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Références

Nat Med. 2019 Apr;25(4):547-553
pubmed: 30936546
Cell Host Microbe. 2017 Aug 9;22(2):207-216
pubmed: 28799906
Immunol Rev. 2017 Jan;275(1):161-182
pubmed: 28133806
Cell Host Microbe. 2016 Mar 9;19(3):292-303
pubmed: 26922989
Nat Biotechnol. 2012 May 07;30(5):423-33
pubmed: 22565972
Immunol Rev. 2013 Jul;254(1):225-44
pubmed: 23772623
Curr Opin Virol. 2013 Jun;3(3):322-31
pubmed: 23806515
Immunity. 2018 May 15;48(5):855-871
pubmed: 29768174
Cold Spring Harb Perspect Biol. 2017 Nov 1;9(11):
pubmed: 28159875
Nat Immunol. 2018 Nov;19(11):1179-1188
pubmed: 30333615

Auteurs

Barton F Haynes (BF)

Departments of Medicine and Immunology, Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. barton.haynes@duke.edu.
ORCID: 0000-0002-2847-1854

Dennis R Burton (DR)

Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
ORCID: 0000-0001-6711-9864

John R Mascola (JR)

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20014, USA.
ORCID: 0000-0002-5293-4695

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Classifications MeSH

Recherchemedicale.com › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antiviraux › Vaccins contre le SIDA › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps neutralisants › Anticorps neutralisants à large spectre › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps antiviraux › Anticorps antideltarétrovirus › Anticorps anti-VIH › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Multiple roles for HIV broadly neutralizing antibodies.
Recherchemedicale.com › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Multiple roles for HIV broadly neutralizing antibodies.