A prospective study evaluating the impact of implementing 'bundled interventions' in reducing surgical site infections among patients undergoing surgery for gynaecological Malignancies.
Adolescent
Adult
Aftercare
Aged
Aged, 80 and over
Anti-Infective Agents, Local
/ therapeutic use
Bandages
Chlorhexidine
/ analogs & derivatives
Cytoreduction Surgical Procedures
Female
Genital Neoplasms, Female
/ surgery
Gynecologic Surgical Procedures
/ methods
Humans
Middle Aged
Patient Care Bundles
/ methods
Patient Education as Topic
Perioperative Care
/ methods
Prospective Studies
Retrospective Studies
Surgical Wound Infection
/ epidemiology
Telephone
Wound Closure Techniques
/ instrumentation
Young Adult
Bundled interventions
Gynaecological malignancy
Surgical site infection
Journal
European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
28
03
2019
revised:
04
10
2019
accepted:
08
10
2019
pubmed:
28
10
2019
medline:
23
4
2020
entrez:
27
10
2019
Statut:
ppublish
Résumé
To investigate the incidence of 30-day surgical site infection (SSI) rate before and after the introduction of evidence-based "bundled interventions" (BI) in gynaecological malignancy (GM).To evaluate the efficacy of BI in reducing SSI rate and readmission rate due to SSI. This prospective interventional study was carried out at a Single University teaching hospital. BIs were implemented in GM laparotomies from March 2016 to June 2018. Baseline SSI rate was determined retrospectively from January 2011 to December 2015. The interventions included patient education, separate closing tray, dressing removal ≤48 h, dismissal with 4% chlorhexidine gluconate and follow up phone call. A 30-day SSI and re-admission rate were assessed. The study included 840 patients, 624 who underwent laparotomy before (PRE) the implementation of BI and 216 after (POST) the implementation. The most common diagnosis was ovarian cancer (OC). There was significant reduction in: overall (p < 0.001) and superficial SSI rates (p < 0.001); OC undergoing surgery without bowel resection (BR) (p < 0.001); and OC with BR (p = 0.003), after implementation of BI. None of the patients had deep organ/space infections or readmissions during the Post-intervention period. The overall compliance for BI was 96.7%. SSI rates significantly decreased in patients aged ≥ 60 years, ASA score ≥ 3, operative time ≥ 240 min, clean contaminated and contaminated surgeries, and prolonged hospital stay (all p < 0.05). Implementation of BI was associated with significant reduction of SSI rate in GM. The intervention remained effective in at-risk patients with non-modifiable clinico-pathologic and surgical factors.
Identifiants
pubmed: 31654860
pii: S0301-2115(19)30449-X
doi: 10.1016/j.ejogrb.2019.10.007
pii:
doi:
Substances chimiques
Anti-Infective Agents, Local
0
chlorhexidine gluconate
MOR84MUD8E
Chlorhexidine
R4KO0DY52L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
21-25Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.