Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of


Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
20 09 2019
Historique:
pubmed: 10 9 2019
medline: 29 7 2020
entrez: 10 9 2019
Statut: ppublish

Résumé

A pharmacophore-directed retrosynthesis strategy applied to rameswaralide provided simplified precursors bearing the common 5,5,6 (red) and 5,5,7 (blue) skeleton present in several cembranoid and norcembranoids from

Identifiants

pubmed: 31498642
doi: 10.1021/acs.orglett.9b02713
pmc: PMC7023684
mid: NIHMS1556763
doi:

Substances chimiques

Biological Products 0
Diterpenes 0
rameswaralide 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7394-7399

Subventions

Organisme : NCI NIH HHS
ID : F31 CA239560
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA006973
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM134910
Pays : United States
Organisme : NIGMS NIH HHS
ID : R37 GM052964
Pays : United States

Références

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Auteurs

Nathanyal J Truax (NJ)

Department of Chemistry & Biochemistry , Baylor University , Waco , Texas 76710 , United States.

Safiat Ayinde (S)

Department of Pharmacology and Molecular Sciences , John Hopkins School of Medicine , 725 North Wolfe Street , Baltimore , Maryland 21205 , United States.

Khoi Van (K)

Department of Chemistry & Biochemistry , Baylor University , Waco , Texas 76710 , United States.

Jun O Liu (JO)

Department of Pharmacology and Molecular Sciences , John Hopkins School of Medicine , 725 North Wolfe Street , Baltimore , Maryland 21205 , United States.

Daniel Romo (D)

Department of Chemistry & Biochemistry , Baylor University , Waco , Texas 76710 , United States.

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Classifications MeSH