Somatic
Biomarkers, Tumor
/ genetics
Erythroblasts
/ pathology
Genetic Predisposition to Disease
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
/ genetics
Mutation
Myelodysplastic Syndromes
/ genetics
Phenotype
Phosphoproteins
/ chemistry
Prognosis
Protein Conformation
RNA Splicing Factors
/ chemistry
Spliceosomes
/ genetics
Structure-Activity Relationship
cancer genetics
haematology
lymphoma
myelodysplasia
spliceosomes
Journal
Journal of clinical pathology
ISSN: 1472-4146
Titre abrégé: J Clin Pathol
Pays: England
ID NLM: 0376601
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
accepted:
12
08
2019
pubmed:
2
9
2019
medline:
2
11
2019
entrez:
2
9
2019
Statut:
ppublish
Résumé
SF3B1 is the largest subunit of the Spliceosome Factor 3b (SF3B) complex and part of the U2 small nuclear ribosomal protein. It functions as an important part of spliceosomal assembly, converting precursor messenger RNA (mRNA) to mRNA ready for ribosomal translation. Mutations of
Identifiants
pubmed: 31473630
pii: jclinpath-2019-205895
doi: 10.1136/jclinpath-2019-205895
doi:
Substances chimiques
Biomarkers, Tumor
0
Phosphoproteins
0
RNA Splicing Factors
0
SF3B1 protein, human
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
778-782Informations de copyright
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.