Pediatric emergency department visit characteristics of the patients on the ketogenic diet.


Journal

Epilepsy & behavior : E&B
ISSN: 1525-5069
Titre abrégé: Epilepsy Behav
Pays: United States
ID NLM: 100892858

Informations de publication

Date de publication:
10 2019
Historique:
received: 28 06 2019
revised: 13 07 2019
accepted: 16 07 2019
pubmed: 10 8 2019
medline: 21 7 2020
entrez: 10 8 2019
Statut: ppublish

Résumé

The ketogenic diet (KD) has been frequently used for the patients with drug-resistant epilepsy in recent years. The management of these patients in emergency departments (EDs) has some difficulties due to the special needs of KD. We aimed to determine the characteristics and the management of the patients on the KD in the pediatric ED setting. Patients who were on the KD and admitted to the ED were included in the study. Demographic, clinical, and laboratory data of all patients were retrospectively reviewed and recorded. There were 105 emergency admissions of 27 patients. The median age of all patients was 55.0 (IQR: 29.0-91.0) months. The most common symptom was vomiting (43.8%). Four patients had upper gastrointestinal bleeding, and one patient had hyperammonemic acute hepatic failure while receiving KD. Of the patients, 41.9% had seizure-related ED admission. Infections were present in 41.9% of the ED visits. The frequency of status epilepticus was significantly lower in the patients who were on the KD for more than 6 months (p < 0.01). In 42.9% of all ED admissions, dextrose containing maintenance fluids was administered mistakenly; although ketosis rate was lower, no seizure was observed in this group. The patients on the KD can be admitted to EDs with intercurrent illnesses or adverse effects of the KD. For accurate management, emergency physicians must be aware of the common reasons for ED admission of these patients and the effects of the KD.

Sections du résumé

BACKGROUND
The ketogenic diet (KD) has been frequently used for the patients with drug-resistant epilepsy in recent years. The management of these patients in emergency departments (EDs) has some difficulties due to the special needs of KD. We aimed to determine the characteristics and the management of the patients on the KD in the pediatric ED setting.
METHODS
Patients who were on the KD and admitted to the ED were included in the study. Demographic, clinical, and laboratory data of all patients were retrospectively reviewed and recorded.
RESULTS
There were 105 emergency admissions of 27 patients. The median age of all patients was 55.0 (IQR: 29.0-91.0) months. The most common symptom was vomiting (43.8%). Four patients had upper gastrointestinal bleeding, and one patient had hyperammonemic acute hepatic failure while receiving KD. Of the patients, 41.9% had seizure-related ED admission. Infections were present in 41.9% of the ED visits. The frequency of status epilepticus was significantly lower in the patients who were on the KD for more than 6 months (p < 0.01). In 42.9% of all ED admissions, dextrose containing maintenance fluids was administered mistakenly; although ketosis rate was lower, no seizure was observed in this group.
CONCLUSION
The patients on the KD can be admitted to EDs with intercurrent illnesses or adverse effects of the KD. For accurate management, emergency physicians must be aware of the common reasons for ED admission of these patients and the effects of the KD.

Identifiants

pubmed: 31398557
pii: S1525-5050(19)30629-8
doi: 10.1016/j.yebeh.2019.106446
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106446

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Aykut Çağlar (A)

Department of Pediatric Emergency Care, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.. Electronic address: aykutcaglar@gmail.com.

Selvinaz Edizer (S)

Department of Pediatric Neurology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Serdar Sarıtaş (S)

Department of Pediatric Neurology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Figen Çelebi Çelik (F)

Department of Pediatrics, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Mehmet Önder (M)

Department of Pediatrics, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Anıl Er (A)

Department of Pediatric Emergency Care, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Emel Ulusoy (E)

Department of Pediatric Emergency Care, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Fatma Akgül (F)

Department of Pediatric Emergency Care, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Aycan Ünalp (A)

Department of Pediatric Neurology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Ünsal Yılmaz (Ü)

Department of Pediatric Neurology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Hurşit Apa (H)

Department of Pediatric Emergency Care, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

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