Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial.


Journal

Complementary therapies in clinical practice
ISSN: 1873-6947
Titre abrégé: Complement Ther Clin Pract
Pays: England
ID NLM: 101225531

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 17 06 2018
revised: 21 06 2019
accepted: 19 07 2019
entrez: 7 8 2019
pubmed: 7 8 2019
medline: 20 11 2019
Statut: ppublish

Résumé

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children. Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks. Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F=2.3, df=1, p=0.13, F=0.57, df=1, p=0.47). Sweet almond may be an effective treatment for ADHD children.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children.
MATERIALS AND METHODS METHODS
Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks.
RESULTS RESULTS
Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F=2.3, df=1, p=0.13, F=0.57, df=1, p=0.47).
CONCLUSION CONCLUSIONS
Sweet almond may be an effective treatment for ADHD children.

Identifiants

pubmed: 31383435
pii: S1744-3881(18)30373-6
doi: 10.1016/j.ctcp.2019.07.008
pii:
doi:

Substances chimiques

Antioxidants 0
Central Nervous System Stimulants 0
Plant Extracts 0
Methylphenidate 207ZZ9QZ49

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Pagination

170-175

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Monireh Sadat Motaharifard (MS)

Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: m-motaharifard@razi.tums.ac.ir.

Mohammad Effatpanah (M)

Ziaeian Hospital, School of Medicine, International Campus, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: m.effatpanah@gmail.com.

Mehrdad Karimi (M)

Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: mehrdadkarimi@yahoo.com.

Shahin Akhondzadeh (S)

Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: S.akhond@neda.net.

Habibollah Rahimi (H)

Clinical Research Development Unit-Matini/Kargarnejad Hospital, Kashan University of Medical Sciences, Kashan, Iran. Electronic address: rahimi_136@yahoo.com.

Seyed Ali Yasrebi (SA)

Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address: Yasrebi.seyedali@gmail.com.

Fatemeh Nejatbakhsh (F)

Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: nejatbakhsh@tums.ac.ir.

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Classifications MeSH