Disappearance of Angiodysplasia Following Transcatheter Aortic Valve Implantation in a Patient with Heyde's Syndrome: A Case Report and Review of the Literature.
Aged, 80 and over
Anemia
/ diagnosis
Angiodysplasia
/ blood
Aortic Valve Stenosis
/ diagnosis
Blood Transfusion
/ methods
Female
Gastrointestinal Hemorrhage
/ diagnosis
Gastroscopy
/ methods
Hemostasis, Surgical
/ methods
Humans
Protein Multimerization
Severity of Illness Index
Stomach
/ blood supply
Transcatheter Aortic Valve Replacement
/ methods
Treatment Outcome
von Willebrand Factor
/ analysis
Aortic stenosis
Gastrointestinal angiodysplasia
Heyde's syndrome
Journal
Journal of atherosclerosis and thrombosis
ISSN: 1880-3873
Titre abrégé: J Atheroscler Thromb
Pays: Japan
ID NLM: 9506298
Informations de publication
Date de publication:
01 Mar 2020
01 Mar 2020
Historique:
pubmed:
6
8
2019
medline:
18
12
2020
entrez:
6
8
2019
Statut:
ppublish
Résumé
An 83-year-old woman with severe aortic stenosis was admitted to our hospital due to heart failure with refractory anemia requiring blood transfusions. She had repetitive bleeding episodes from endoscopically proven angiodysplasia in the stomach. Moreover, she repeatedly underwent endoscopic argon plasma coagulation for hemostasis. Importantly, she had a deficiency of the high-molecular-weight (HMW) multimers of von Willebrand factor (VWF), and she was diagnosed with Heyde's syndrome.After she underwent transcatheter aortic valve implantation (TAVI), aortic valve area and mean left ventricular aorta pressure gradient improved. Notably, endoscopy showed cessation of bleeding at 10 days after TAVI and the disappearance of angiodysplasia at 4 months after TAVI. Even at 2 years after TAVI, follow-up endoscopy showed remaining free of angiodysplasia in the stomach. She experienced no episodes of anemia since TAVI procedure. Additionally, analysis of HMW multimers demonstrated immediate and lasting recovery after TAVI.Recovery of HMW multimers of VWF with cessation of gastrointestinal bleeding following aortic valve replacement has been previously reported in a patient diagnosed with Heyde's syndrome. To the best our knowledge, this is the first case to demonstrate that angiodysplasia disappears after TAVI for a long term with endoscopic images in a patient with Heyde's syndrome. Here, we summarized case reports of patients with Heyde's syndrome that required aortic valve intervention. Cessation of gastrointestinal bleeding and anemia after aortic valve intervention for severe aortic stenosis may be attributed not only to recovery of HMW multimers of VWF but also to the disappearance of angiodysplasia.
Identifiants
pubmed: 31378751
doi: 10.5551/jat.49239
pmc: PMC7113142
doi:
Substances chimiques
von Willebrand Factor
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
271-277Références
Blood. 2011 Jan 20;117(3):1071-80
pubmed: 21048155
Hepatology. 2006 Jul;44(1):53-61
pubmed: 16799972
Eur J Cardiothorac Surg. 2018 Nov 1;54(5):841-846
pubmed: 29741685
Dig Surg. 2006;23(5-6):387-8
pubmed: 17299265
Gastroenterology. 2011 Nov;141(5):1629-37.e1-4
pubmed: 21784047
Aorta (Stamford). 2014 Apr 01;2(2):74-6
pubmed: 26798717
Thorac Cardiovasc Surg. 1990 Dec;38(6):374-6
pubmed: 2291237
Asian Cardiovasc Thorac Ann. 2014 Jun;22(5):592-4
pubmed: 24867036
Ann Thorac Surg. 1987 Nov;44(5):554-5
pubmed: 3499882
Intern Med. 2017 Sep 15;56(18):2431-2433
pubmed: 28824071
Pathophysiol Haemost Thromb. 2005;34(1):35-40
pubmed: 16293984
N Engl J Med. 2016 Jul 28;375(4):335-44
pubmed: 27464202
J Atheroscler Thromb. 2016 Oct 1;23(10):1150-1158
pubmed: 27052664
J Cardiol Cases. 2015 Dec 11;13(3):87-89
pubmed: 30546614
Blood. 2018 Jul 12;132(2):132-140
pubmed: 29866817
Gastroenterology. 1953 May;24(1):118-23
pubmed: 13052170
J Cardiothorac Surg. 2017 Aug 8;12(1):65
pubmed: 28789675
Curr Cardiol Rev. 2011 Feb;7(1):47-9
pubmed: 22294975
An Sist Sanit Navar. 2013 Sep 06;36(2):339-45
pubmed: 24008540
Acta Chir Belg. 1993 Jan-Feb;93(1):31-3
pubmed: 8470439
Ann Thorac Surg. 1986 Oct;42(4):477-80
pubmed: 3490235
Blood Coagul Fibrinolysis. 2011 Oct;22(7):622-3
pubmed: 21760480
Am J Case Rep. 2018 Aug 07;19:924-926
pubmed: 30082678
Gut. 1964 Oct;5:417-21
pubmed: 14218259
Thromb Haemost. 2004 Feb;91(2):267-75
pubmed: 14961153
Helicobacter. 2011 Dec;16(6):444-51
pubmed: 22059395
Am J Cardiol. 2014 Sep 15;114(6):953-4
pubmed: 25208564
Anadolu Kardiyol Derg. 2012 Dec;12(8):691-3
pubmed: 22989800
Chest. 1988 Oct;94(4):891-2
pubmed: 3262491
J Thromb Haemost. 2017 Jan;15(1):13-20
pubmed: 27778439
N Engl J Med. 1953 Jun 18;248(25):1057-8
pubmed: 13054886
J Cardiol Cases. 2012 Mar 16;5(2):e128-e131
pubmed: 30532921
Thromb Haemost. 2009 Apr;101(4):773-4
pubmed: 19350125
Presse Med. 2012 Jul;41(7-8):763-6
pubmed: 22155070
Ann Thorac Surg. 2017 Mar;103(3):e225-e226
pubmed: 28219552
J Atheroscler Thromb. 2015;22(11):1115-23
pubmed: 26269004
J Nippon Med Sch. 2017;84(4):193-197
pubmed: 28978901
N Engl J Med. 2003 Jul 24;349(4):343-9
pubmed: 12878741
Clin J Gastroenterol. 2009 Jun;2(3):187-189
pubmed: 26192293
Clin Nucl Med. 2005 Apr;30(4):231-5
pubmed: 15764876
J Clin Invest. 1986 Dec;78(6):1456-61
pubmed: 3491092
J Clin Med Res. 2015 Nov;7(11):907-10
pubmed: 26491506
Arq Bras Cardiol. 2017 Apr;108(4):378-380
pubmed: 28538766
J Community Hosp Intern Med Perspect. 2018 Jun 12;8(3):127-129
pubmed: 29915650
Heart Surg Forum. 2014 Oct 1;17(5):E258-60
pubmed: 25367238
Med Sci Monit. 2010 Sep;16(9):CS107-9
pubmed: 20802419
Aliment Pharmacol Ther. 2014 Jan;39(1):15-34
pubmed: 24138285
Scand J Clin Lab Invest. 2001;61(6):421-9
pubmed: 11681531
J Card Surg. 2013 Jul;28(4):414-6
pubmed: 23692692
Ann Thorac Surg. 2007 Jan;83(1):287-8
pubmed: 17184682
Case Rep Med. 2012;2012:946764
pubmed: 22919400
Isr Med Assoc J. 2013 Jul;15(7):387-9
pubmed: 23943988
N Engl J Med. 2012 Nov 15;367(20):1954-6
pubmed: 23150964
Int J Surg Case Rep. 2018;53:281-284
pubmed: 30448636
Am J Gastroenterol. 1999 Apr;94(4):1070-6
pubmed: 10201485
Hepatology. 1996 Jun;23(6):1377-83
pubmed: 8675154