Structural basis for the clamping and Ca


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
03 06 2019
Historique:
received: 30 11 2018
accepted: 08 05 2019
entrez: 5 6 2019
pubmed: 5 6 2019
medline: 25 6 2019
Statut: epublish

Résumé

Synapotagmin-1 (Syt1) interacts with both SNARE proteins and lipid membranes to synchronize neurotransmitter release to calcium (Ca

Identifiants

pubmed: 31160571
doi: 10.1038/s41467-019-10391-x
pii: 10.1038/s41467-019-10391-x
pmc: PMC6546687
doi:

Substances chimiques

Membrane Lipids 0
Neurotransmitter Agents 0
SNARE Proteins 0
Synaptotagmin I 0
Syt1 protein, rat 0
Magnesium I38ZP9992A
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2413

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK027044
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM110530
Pays : United States
Organisme : U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases)
ID : DK027044
Pays : International

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Auteurs

Kirill Grushin (K)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.

Jing Wang (J)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.

Jeff Coleman (J)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.

James E Rothman (JE)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.

Charles V Sindelar (CV)

Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA. charles.sindelar@yale.edu.

Shyam S Krishnakumar (SS)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA. shyam.krishnakumar@yale.edu.
Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queens Square House, London, WC1 3BG, UK. shyam.krishnakumar@yale.edu.

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Classifications MeSH