Football's InfluencE on Lifelong health and Dementia risk (FIELD): protocol for a retrospective cohort study of former professional footballers.
Athletes
Case-Control Studies
Cause of Death
Chronic Disease
Chronic Traumatic Encephalopathy
Dementia
/ epidemiology
Humans
Incidence
Mental Disorders
/ epidemiology
Neurodegenerative Diseases
/ epidemiology
Occupational Exposure
Proportional Hazards Models
Retrospective Studies
Risk Factors
Scotland
/ epidemiology
Soccer
dementia
neurology
public health
sports medicine
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
22 05 2019
22 05 2019
Historique:
entrez:
25
5
2019
pubmed:
28
5
2019
medline:
30
5
2020
Statut:
epublish
Résumé
In the past decade, evidence has emerged suggesting a potential link between contact sport participation and increased risk of late neurodegenerative disease, in particular chronic traumatic encephalopathy. While there remains a lack of clear evidence to test the hypothesis that contact sport participation is linked to an increased incidence of dementia, there is growing public concern regarding the risk. There is, therefore, a pressing need for research to gain greater understanding of the potential risks involved in contact sports participation, and to contextualise these within holistic health benefits of sport. Football's InfluencE on Lifelong health and Dementia risk is designed as a retrospective cohort study, with the aim to analyse data from former professional footballers (FPF) in order to assess the incidence of neurodegenerative disease in this population. Comprehensive electronic medical and death records will be analysed and compared with those of a demographically matched population control cohort. As well as neurodegenerative disease incidence, all-cause, and disease-specific mortality, will be analysed in order to assess lifelong health. Cox proportional hazards models will be run to compare the data collected from FPFs to matched population controls. Approvals for study have been obtained from the University of Glasgow College of Medical, Veterinary and Life Sciences Research Ethics Committee (Project Number 200160147) and from National Health Service Scotland's Public Benefits and Privacy Panel (Application 1718-0120).
Identifiants
pubmed: 31123003
pii: bmjopen-2018-028654
doi: 10.1136/bmjopen-2018-028654
pmc: PMC6538057
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e028654Subventions
Organisme : NINDS NIH HHS
ID : R01 NS094003
Pays : United States
Informations de copyright
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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