Football's InfluencE on Lifelong health and Dementia risk (FIELD): protocol for a retrospective cohort study of former professional footballers.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
22 05 2019
Historique:
entrez: 25 5 2019
pubmed: 28 5 2019
medline: 30 5 2020
Statut: epublish

Résumé

In the past decade, evidence has emerged suggesting a potential link between contact sport participation and increased risk of late neurodegenerative disease, in particular chronic traumatic encephalopathy. While there remains a lack of clear evidence to test the hypothesis that contact sport participation is linked to an increased incidence of dementia, there is growing public concern regarding the risk. There is, therefore, a pressing need for research to gain greater understanding of the potential risks involved in contact sports participation, and to contextualise these within holistic health benefits of sport. Football's InfluencE on Lifelong health and Dementia risk is designed as a retrospective cohort study, with the aim to analyse data from former professional footballers (FPF) in order to assess the incidence of neurodegenerative disease in this population. Comprehensive electronic medical and death records will be analysed and compared with those of a demographically matched population control cohort. As well as neurodegenerative disease incidence, all-cause, and disease-specific mortality, will be analysed in order to assess lifelong health. Cox proportional hazards models will be run to compare the data collected from FPFs to matched population controls. Approvals for study have been obtained from the University of Glasgow College of Medical, Veterinary and Life Sciences Research Ethics Committee (Project Number 200160147) and from National Health Service Scotland's Public Benefits and Privacy Panel (Application 1718-0120).

Identifiants

pubmed: 31123003
pii: bmjopen-2018-028654
doi: 10.1136/bmjopen-2018-028654
pmc: PMC6538057
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e028654

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS094003
Pays : United States

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Emma R Russell (ER)

Glasgow Brain Injury Research Group, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.

Katy Stewart (K)

Sport and Exercise Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Hampden Sports Clinic, Hampden Stadium, Glasgow, UK.

Daniel F Mackay (DF)

Public Health, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.

John MacLean (J)

Sport and Exercise Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Hampden Sports Clinic, Hampden Stadium, Glasgow, UK.

Jill P Pell (JP)

Public Health, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.

William Stewart (W)

Glasgow Brain Injury Research Group, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
Department of Neuropathology, Queen Elizabeth University Hospital, Glasgow, UK.

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Classifications MeSH