Pressure support ventilation, sigh adjunct to pressure support ventilation, and neurally adjusted ventilatory assist in infants after cardiac surgery: A physiologic crossover randomized study.
SIGH
asynchronies
neurally adjusted ventilatory assist
pediatric cardiac surgery
pressure support ventilation
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
26
12
2018
revised:
25
03
2019
accepted:
25
03
2019
pubmed:
21
4
2019
medline:
13
3
2020
entrez:
21
4
2019
Statut:
ppublish
Résumé
We sought to compare gas exchange, respiratory mechanics, and asynchronies during pressure support ventilation (PSV), sigh adjunct to PSV (PSV SIGH), and neurally adjusted ventilatory assist (NAVA) in hypoxemic infants after cardiac surgery. Prospective, single-center, crossover, randomized physiologic study. Tertiary-care pediatric intensive care unit. Fourteen hypoxemic infants (median age 11.5 days [8.7-74]). The protocol begins with a 1 hour step of PSV, followed by two consecutive steps in PSV SIGH and NAVA in random order, with a washout period of 30 minutes (PSV) between them. Three infants presented an irregular Eadi signal because of diaphragmatic paralysis and were excluded from analysis. For the remaining 11 infants, PaO The adjunct of one SIGH per minute to PSV improved oxygenation and lung mechanics while NAVA provided the best patient-ventilator synchrony in infants after cardiac surgery.
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1078-1086Informations de copyright
© 2019 Wiley Periodicals, Inc.