CACNB2 is associated with aberrant RAS-MAPK signaling in hypertensive Dahl Salt-Sensitive rats.

Animals Calcium Channels, L-Type / genetics HEK293 Cells Humans Hypertension / genetics Mitogen-Activated Protein Kinases / genetics Rats Rats, Inbred Dahl Signal Transduction Sodium Chloride, Dietary / metabolism Up-Regulation ras Proteins / genetics
CACNB2 Dahl SS rat L-type calcium channel RAS–MAPK

Journal

Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516

Informations de publication

Date de publication:
04 06 2019
Historique:
received: 22 03 2019
accepted: 31 03 2019
pubmed: 18 4 2019
medline: 23 6 2020
entrez: 18 4 2019
Statut: ppublish

Résumé

Several independent genome-wide association studies (GWAS) have indicated that calcium (Ca

Identifiants

DOI: 10.1016/j.bbrc.2019.03.215 PMID: 30992131
pubmed: 30992131
pii: S0006-291X(19)30622-9
doi: 10.1016/j.bbrc.2019.03.215
pii:
doi:

Substances chimiques

Cacnb2 protein, rat 0
Calcium Channels, L-Type 0
Sodium Chloride, Dietary 0
Mitogen-Activated Protein Kinases EC 2.7.11.24
ras Proteins EC 3.6.5.2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

760-765

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Vishnuprabu Durairaj Pandian (V)

Department of Physiology and Pharmacology, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.

David R Giovannucci (DR)

Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.

Guillermo Vazquez (G)

Department of Physiology and Pharmacology, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.

Sivarajan Kumarasamy (S)

Department of Physiology and Pharmacology, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA. Electronic address: Sivarajan.Kumarasamy@utoledo.edu.

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Classifications MeSH

Recherchemedicale.com › Eucaryotes › Animaux › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux calciques › Canaux calciques de type L › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Cellules › Cellules épithéliales › Cellules HEK293 › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Maladies cardiovasculaires › Maladies vasculaires › Hypertension artérielle › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Mitogen-Activated Protein Kinases › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Lignées consanguines de rats › Rats de lignée Dahl › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Phénomènes physiologiques cellulaires › Transduction du signal › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Produits chimiques inorganiques › Composés du sodium › Sodium alimentaire › Chlorure de sodium alimentaire › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Régulation positive › CACNB2 is associated with aberrant RAS-MAPK...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines G › Protéines G monomériques › Protéines G ras › CACNB2 is associated with aberrant RAS-MAPK...