Oncogenic


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
23 04 2019
Historique:
pubmed: 6 4 2019
medline: 26 3 2020
entrez: 6 4 2019
Statut: ppublish

Résumé

The

Identifiants

pubmed: 30948643
pii: 1821093116
doi: 10.1073/pnas.1821093116
pmc: PMC6486754
doi:

Substances chimiques

Class I Phosphatidylinositol 3-Kinases EC 2.7.1.137
PIK3CA protein, human EC 2.7.1.137

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8380-8389

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Cancer Research UK
ID : 25722
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12012/5
Pays : United Kingdom

Informations de copyright

Copyright © 2019 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

Conflict of interest statement: B.V. is a consultant for Venthera (Palo Alto, CA), iOnctura (Geneva, Switzerland), and Karus Therapeutics (Oxford, United Kingdom). N.M. has received consultancy fees from Achilles Therapeutics.

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Auteurs

Ralitsa R Madsen (RR)

Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, United Kingdom.
Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.

Rachel G Knox (RG)

Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, United Kingdom.

Wayne Pearce (W)

University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.

Saioa Lopez (S)

Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.
Cancer Genome Evolution Research Group, University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.

Betania Mahler-Araujo (B)

Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
Histopathology Department, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge CB2 0QQ, United Kingdom.

Nicholas McGranahan (N)

Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.
Cancer Genome Evolution Research Group, University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.

Bart Vanhaesebroeck (B)

University College London Cancer Institute, University College London, London WC1E 6DD, United Kingdom.

Robert K Semple (RK)

Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, United Kingdom; rsemple@ed.ac.uk.
National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, United Kingdom.
Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.

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Classifications MeSH