Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
06 2019
Historique:
received: 25 06 2018
revised: 25 09 2018
accepted: 11 12 2018
pubmed: 13 1 2019
medline: 11 11 2020
entrez: 13 1 2019
Statut: ppublish

Résumé

Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited. A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed. Six patients (8%) had postoperative complications, but no treatment-related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five-year disease-specific survival (DSS), overall survival, and laryngectomy-free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates. Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.

Sections du résumé

BACKGROUND
Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited.
METHODS
A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed.
RESULTS
Six patients (8%) had postoperative complications, but no treatment-related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five-year disease-specific survival (DSS), overall survival, and laryngectomy-free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates.
CONCLUSIONS
Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.

Identifiants

pubmed: 30636186
doi: 10.1002/hed.25616
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1816-1823

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Juan P Rodrigo (JP)

Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain.

Fabian García-Velasco (F)

Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain.

Petra Ambrosch (P)

Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University of Kiel, Kiel, Germany.

Vincent Vander Poorten (V)

Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
Department of Oncology, Section Head and Neck Oncology, KU Leuven, Leuven, Belgium.

Carlos Suárez (C)

Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain.

Andrés Coca-Pelaz (A)

Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain.

Primoz Strojan (P)

Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.

Kate Hutcheson (K)

Department of Head and Neck Surgery, Section of Speech Pathology and Audiology, MD Anderson Cancer Center, Houston, Texas.

Benedikt J Folz (BJ)

ENT Department, Karl Hansen Clinic, Bad Lippspringe, Germany.

Manuel Bernal-Sprekelsen (M)

Department of Otolaryngology, University of Valencia, Valencia, Spain.

Alessandra Rinaldo (A)

Otorhinolaryngology-Head and neck surgery, University of Udine School of Medicine, Udine, Italy.

Carl E Silver (CE)

Department of Surgery, University of Arizona College of Medicine, Phoenix, Arizona.

Alfio Ferlito (A)

International Head and Neck Scientific Group, Padua, Italy.

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Classifications MeSH