Plantar Ulcers and Neuropathic Arthropathies: Associated Diseases, Polyneuropathy Correlates, and Risk Covariates.
Age Distribution
Aged
Arthropathy, Neurogenic
/ diagnosis
Cohort Studies
Comorbidity
Disease Progression
Female
Foot Ulcer
/ diagnosis
Humans
Incidence
Male
Middle Aged
Plantar Plate
/ physiopathology
Polyneuropathies
/ diagnosis
Prognosis
Retrospective Studies
Risk Assessment
Severity of Illness Index
Sex Distribution
Wound Healing
/ physiology
Journal
Advances in skin & wound care
ISSN: 1538-8654
Titre abrégé: Adv Skin Wound Care
Pays: United States
ID NLM: 100911021
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
pubmed:
10
1
2019
medline:
6
8
2019
entrez:
10
1
2019
Statut:
ppublish
Résumé
To evaluate the associated diseases, polyneuropathy correlates, and risk covariates of neuropathic plantar ulcers (PUs) and neuropathic arthropathies (NAs). The authors conducted a retrospective, observational study over 3.5 years of 69 patients with neuropathy, NA, or PU seen in a wound clinic who also had a comprehensive neurologic evaluation and neurophysiologic testing. Comparisons were made to a population representative cohort of patients with diabetes mellitus (DM; n = 259). Of the 69 wound clinic patients, 32 had PUs, 14 had NAs, and 23 had both. Of the 61 adequately assessed patients, 37 (61%) had DM, 22 (36%) had no known associated disease, and 2 (3%) had hereditary sensory and autonomic neuropathy. Of the 37 patients with DM, 35 had distal polyneuropathy, and 2 did not. In 22 patients with chronic idiopathic axonal polyneuropathy, 20 had distal polyneuropathy. Although DM was the disease most commonly associated with PUs and NAs, chronic hyperglycemia may not have been the major underlying risk factor. The major risk covariates are sensation loss from polyneuropathy, old age, obesity, repetitive foot injury, and inadequate foot care or treatment. Physicians and other healthcare providers can help by identifying patients at risk and instituting measures such as adequate foot care to decrease these risks.
Identifiants
pubmed: 30624254
doi: 10.1097/01.ASW.0000550591.08674.98
doi:
Types de publication
Comparative Study
Journal Article
Observational Study
Langues
eng