Gangrenous appendicitis: No longer complicated.


Journal

Journal of pediatric surgery
ISSN: 1531-5037
Titre abrégé: J Pediatr Surg
Pays: United States
ID NLM: 0052631

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 12 02 2018
revised: 10 10 2018
accepted: 21 10 2018
pubmed: 16 12 2018
medline: 21 5 2019
entrez: 16 12 2018
Statut: ppublish

Résumé

Appendicitis presents on a spectrum ranging from inflammation to gangrene to perforation. Studies suggest that gangrenous appendicitis has lower postoperative infection rates relative to perforated cases. We hypothesized that gangrenous appendicitis could be successfully treated as simple appendicitis, reducing length of stay (LOS) and antibiotic usage without increasing postoperative infections. In February 2016, we strictly defined complex appendicitis as a hole in the appendix, extraluminal fecalith, diffuse pus or a well-formed abscess. We switched gangrenous appendicitis to a simple pathway and reviewed all patients undergoing laparoscopic appendectomy for 12 months before (Group 1) and 12 months after (Group 2) the protocol change. Data collected included demographics, appendicitis classification, LOS, presence of a postoperative infection, and 30-day readmissions. Patients in Group 1 and Group 2 were similar, but more cases of simple appendicitis occurred in Group 2. Average LOS for gangrenous appendicitis patients decreased from 2.5 to 1.4 days (p < 0.001) and antibiotic doses decreased from 5.2 to 1.3 (p < 0.001). Only one gangrenous appendicitis patient required readmission, and one patient in each group developed a superficial infection; there were no postoperative abscesses. Gangrenous appendicitis can be safely treated as simple appendicitis without increasing postoperative infections or readmissions. Prognosis study. Level II.

Sections du résumé

BACKGROUND BACKGROUND
Appendicitis presents on a spectrum ranging from inflammation to gangrene to perforation. Studies suggest that gangrenous appendicitis has lower postoperative infection rates relative to perforated cases. We hypothesized that gangrenous appendicitis could be successfully treated as simple appendicitis, reducing length of stay (LOS) and antibiotic usage without increasing postoperative infections.
METHODS METHODS
In February 2016, we strictly defined complex appendicitis as a hole in the appendix, extraluminal fecalith, diffuse pus or a well-formed abscess. We switched gangrenous appendicitis to a simple pathway and reviewed all patients undergoing laparoscopic appendectomy for 12 months before (Group 1) and 12 months after (Group 2) the protocol change. Data collected included demographics, appendicitis classification, LOS, presence of a postoperative infection, and 30-day readmissions.
RESULTS RESULTS
Patients in Group 1 and Group 2 were similar, but more cases of simple appendicitis occurred in Group 2. Average LOS for gangrenous appendicitis patients decreased from 2.5 to 1.4 days (p < 0.001) and antibiotic doses decreased from 5.2 to 1.3 (p < 0.001). Only one gangrenous appendicitis patient required readmission, and one patient in each group developed a superficial infection; there were no postoperative abscesses.
CONCLUSIONS CONCLUSIONS
Gangrenous appendicitis can be safely treated as simple appendicitis without increasing postoperative infections or readmissions.
TYPE OF STUDY METHODS
Prognosis study.
LEVEL OF EVIDENCE METHODS
Level II.

Identifiants

pubmed: 30551843
pii: S0022-3468(18)30723-1
doi: 10.1016/j.jpedsurg.2018.10.064
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

718-722

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Andrew B Nordin (AB)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; State University of New York University at Buffalo, Department of General Surgery, 100 High St, Buffalo, NY 14203. Electronic address: abnordin@buffalo.edu.

Karen Diefenbach (K)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; The Ohio State University College of Medicine, 370 W 9th Ave, Columbus, OH, 43210. Electronic address: Karen.Diefenbach@nationwidechildrens.org.

Stephen P Sales (SP)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205. Electronic address: Stephen.Sales@nationwidechildrens.org.

Jeff Christensen (J)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205. Electronic address: Jeff.Christensen@nationwidechildrens.org.

Gail E Besner (GE)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; The Ohio State University College of Medicine, 370 W 9th Ave, Columbus, OH, 43210. Electronic address: Gail.Besner@nationwidechildrens.org.

Brian D Kenney (BD)

Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; The Ohio State University College of Medicine, 370 W 9th Ave, Columbus, OH, 43210. Electronic address: Brian.Kenney@nationwidechildrens.org.

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Classifications MeSH