The impact of obesity on SLE disease activity: findings from the Southern California Lupus Registry (SCOLR).
Cardiovascular diseases
Disease activity index
Obesity
Systemic lupus erythematosus
Journal
Clinical rheumatology
ISSN: 1434-9949
Titre abrégé: Clin Rheumatol
Pays: Germany
ID NLM: 8211469
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
23
07
2018
accepted:
10
10
2018
revised:
18
09
2018
pubmed:
26
10
2018
medline:
29
5
2019
entrez:
26
10
2018
Statut:
ppublish
Résumé
The role of obesity in systemic lupus erythematosus (SLE) remains controversial. Studies have linked adiposity with a heightened risk of clinical complications including neurocognitive decline, renal impairment, dampened physical activity, and depressed quality of life-but not disease activity. We aimed to reexamine whether obesity in SLE patients independently associates with higher disease activity. Adult patients with SLE were recruited from the longitudinal, multi-ethnic Southern California Lupus Registry (SCOLR). Disease status was ascertained by calculating SLE Disease Activity Index (SLEDAI), which was then statistically analyzed for association with increased body mass index (BMI) by univariable and multivariable regression analyses. One hundred and thirty-seven patients were included in the study; 37% were obese (BMI ≥ 30 kg/m
Identifiants
pubmed: 30357495
doi: 10.1007/s10067-018-4336-3
pii: 10.1007/s10067-018-4336-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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