Effects of ethanol on human periodontal ligament fibroblasts subjected to static compressive force.
Alcohol
Compressive force
Ethanol
Orthodontics
PDL
Periodontal ligament fibroblast
Journal
Alcohol (Fayetteville, N.Y.)
ISSN: 1873-6823
Titre abrégé: Alcohol
Pays: United States
ID NLM: 8502311
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
27
04
2018
revised:
08
10
2018
accepted:
09
10
2018
pubmed:
20
10
2018
medline:
7
5
2020
entrez:
19
10
2018
Statut:
ppublish
Résumé
Consumption of toxic substances such as alcohol is widespread in the general population and thus also in patients receiving orthodontic treatment. Since human periodontal ligament (hPDL) fibroblasts play a key role in orthodontic tooth movement (OTM) by expressing cytokines and chemokines, we wanted to clarify whether ethanol modulates the physiological activity and expression pattern of hPDL fibroblasts during static compressive force application. We pre-incubated hPDL fibroblasts for 24 h with different ethanol concentrations, corresponding to casual (0.041% blood alcohol concentration [BAC], % by volume) and excessive (0.179%) alcohol consumption. At each ethanol concentration, we incubated the cells for another 48 h with and without an additional physiological compressive force of 2 g/cm
Identifiants
pubmed: 30336201
pii: S0741-8329(18)30124-1
doi: 10.1016/j.alcohol.2018.10.004
pii:
doi:
Substances chimiques
Ethanol
3K9958V90M
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
59-70Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.