Altered bone microarchitecture in a type 1 diabetes mouse model Ins2
Animals
Apoptosis
Biomarkers
/ metabolism
Blood Glucose
/ metabolism
Body Weight
Cancellous Bone
/ pathology
Cartilage
/ metabolism
Cortical Bone
/ pathology
Diabetes Mellitus, Type 1
/ blood
Disease Models, Animal
Femur
/ diagnostic imaging
Gene Expression Regulation
Growth Plate
/ pathology
Insulin
/ blood
Leptin
/ blood
Male
Mice, Inbred C57BL
Organ Size
Tartrate-Resistant Acid Phosphatase
/ metabolism
Ins2Akita mouse
bone
cartilage
diabetes
insulin
leptin
Journal
Journal of cellular physiology
ISSN: 1097-4652
Titre abrégé: J Cell Physiol
Pays: United States
ID NLM: 0050222
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
09
11
2017
accepted:
24
09
2018
pubmed:
15
10
2018
medline:
9
4
2020
entrez:
15
10
2018
Statut:
ppublish
Résumé
Type 1 diabetes mellitus (T1DM) has been associated to several cartilage and bone alterations including growth retardation, increased fracture risk, and bone loss. To determine the effect of long term diabetes on bone we used adult and aging Ins2
Substances chimiques
Biomarkers
0
Blood Glucose
0
Ins2 protein, mouse
0
Insulin
0
Leptin
0
Acp5 protein, mouse
EC 3.1.3.2
Tartrate-Resistant Acid Phosphatase
EC 3.1.3.2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
9338-9350Informations de copyright
© 2018 Wiley Periodicals, Inc.