A prediction model relating the extent of intraoperative fascia preservation to erectile dysfunction after nerve-sparing robot-assisted radical prostatectomy.
Aged
Cohort Studies
Erectile Dysfunction
/ epidemiology
Fascia
Humans
Male
Middle Aged
Models, Statistical
Organ Sparing Treatments
Penile Erection
/ physiology
Postoperative Complications
/ etiology
Predictive Value of Tests
Prostatectomy
/ adverse effects
Prostatic Neoplasms
/ surgery
Recovery of Function
/ physiology
Robotic Surgical Procedures
/ adverse effects
Treatment Outcome
Erectile dysfunction
IIEF
Nerve-sparing
Prediction model
Prostatectomy
RARP
Journal
Journal of robotic surgery
ISSN: 1863-2491
Titre abrégé: J Robot Surg
Pays: England
ID NLM: 101300401
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
02
07
2018
accepted:
26
08
2018
pubmed:
5
9
2018
medline:
14
11
2019
entrez:
5
9
2018
Statut:
ppublish
Résumé
Robot-assisted radical prostatectomy (RARP) is performed in patients with prostate cancer. Unfortunately, 10-46% of patients may still suffer from limited erectile function (EF) after RARP. This study aimed to develop a prediction model based on the extent of fascia preservation (FP) and postoperative EF after RARP. A previously developed FP score quantizing the extent and regions of nerve-preservation was determined in a cohort of 1241 patients who underwent RARP. The predictive value of the FP score for post-prostatectomy EF (following the international index erectile function (IIEF) score, EF domain) was analyzed. To increase the predictive value of the scoring system, the FP regions were related to postoperative EF, nerve distribution and co-morbidity factors. Finally, a prediction model for EF was developed based on the studied cohort. When corrected for the preoperative IIEF-EF, the FP score was shown to be a significant denominator for IIEF (p = 2.5 × 10
Identifiants
pubmed: 30178300
doi: 10.1007/s11701-018-0867-5
pii: 10.1007/s11701-018-0867-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
455-462Références
BJU Int. 2004 Nov;94(7):1071-6
pubmed: 15541130
J Endourol. 2004 Sep;18(7):611-9; discussion 619
pubmed: 15597646
Eur Urol. 2006 Jun;49(6):1065-73; discussion 1073-4
pubmed: 16597485
Urology. 2006 Sep;68(3):587-91; discussion 591-2
pubmed: 17010729
Eur Urol. 2008 May;53(5):931-40
pubmed: 18082320
J Urol. 2008 Dec;180(6):2557-64; discussion 2564
pubmed: 18930504
Urology. 2009 Apr;73(4):816-21
pubmed: 19195692
J Sex Med. 2010 Feb;7(2 Pt 1):839-45
pubmed: 19912486
Eur Urol. 2010 Feb;57(2):179-92
pubmed: 19931974
Surg Radiol Anat. 2010 Aug;32(7):663-7
pubmed: 20429006
J Sex Med. 2010 Jul;7(7):2521-31
pubmed: 20487236
BJU Int. 2010 Dec;106(11):1612-7
pubmed: 20590546
Nat Biotechnol. 2011 Apr;29(4):352-6
pubmed: 21297616
Int J Impot Res. 2012 Jan-Feb;24(1):11-9
pubmed: 21850014
BJU Int. 2011 Sep;108(6 Pt 2):984-92
pubmed: 21917101
Eur Urol. 2012 Mar;61(3):571-6
pubmed: 22225830
J Sex Med. 2012 Mar;9(3):903-8
pubmed: 22240189
Eur Urol. 2012 Sep;62(3):418-30
pubmed: 22749850
Prostate Int. 2013;1(4):139-45
pubmed: 24392437
Molecules. 2014 Jul 08;19(7):9876-92
pubmed: 25006792
J Sex Med. 2015 Jun;12(6):1490-6
pubmed: 25689342
Urol Oncol. 2015 May;33(5):203.e11-8
pubmed: 25814146
J Robot Surg. 2016 Sep;10(3):221-6
pubmed: 26994775
J Sex Med. 2016 Apr;13(4):669-78
pubmed: 27045263
Oral Oncol. 2016 Sep;60:48-54
pubmed: 27531872
J Urol. 1982 Sep;128(3):492-7
pubmed: 7120554