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Acides aminés, peptides et protéines
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Lectines
Lectines liant le mannose
Lectine liant le mannose
Lectine liant le mannose : Questions médicales fréquentes
Diagnostic
5
Déficience immunitaire
Lectine liant le mannose
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Système immunitaire
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Lectine liant le mannose
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5
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5
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5
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5
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Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Maladies auto-immunes
Déficience immunitaire
Habitudes de vie
Facteurs de risque
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"position": 12,
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"name": "Les vaccinations sont-elles recommandées ?",
"position": 13,
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"position": 14,
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"position": 15,
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{
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"name": "Quels traitements sont disponibles pour la déficience en lectine ?",
"position": 16,
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"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 17,
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"text": "La thérapie génique est en recherche, mais pas encore largement disponible."
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"name": "Comment gérer les infections récurrentes ?",
"position": 18,
"acceptedAnswer": {
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"name": "Les traitements sont-ils personnalisés ?",
"position": 19,
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"@type": "Question",
"name": "Y a-t-il des effets secondaires aux traitements ?",
"position": 20,
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{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec une déficience en lectine ?",
"position": 21,
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"text": "Des infections graves, des maladies auto-immunes et des complications pulmonaires."
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{
"@type": "Question",
"name": "Les infections peuvent-elles entraîner des hospitalisations ?",
"position": 22,
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"text": "Oui, des infections sévères peuvent nécessiter une hospitalisation prolongée."
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{
"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
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"@type": "Answer",
"text": "Certaines études suggèrent un risque accru de cancers chez les patients déficients."
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{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Comment surveiller les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et des tests peuvent aider à détecter les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour la déficience en lectine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, certaines maladies génétiques et l'âge avancé."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes augmentent-elles le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les maladies auto-immunes peuvent être associées à une déficience en lectine."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études montrent que le risque peut être plus élevé chez les hommes."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des environnements avec une forte exposition aux infections augmentent le risque."
}
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{
"@type": "Question",
"name": "Les habitudes de vie affectent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme et une mauvaise alimentation peuvent augmenter le risque."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 09/02/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, India.
Publications dans "Lectine liant le mannose" :
4 publications dans cette catégorie
Affiliations :
Department of Human Genetics, Guru Nanak Dev University, Amritsar, India.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, India.
Department of Biological Sciences, George Washington University, Washington, DC 20052, USA.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Immunopathology, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Immunopathology, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Immunopathology, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
GLYcoDiag, 2 rue du Cristal, 45100 Orléans, France.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
GLYcoDiag, 2 rue du Cristal, 45100 Orléans, France.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Discipline of Genetics, School of Life Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Animal Sciences, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Animal Sciences, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Animal Sciences, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Internal Medicine Post Graduate, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil; Department of Medicine, Positivo University, Curitiba, Brazil. Electronic address: renatonisihara@gmail.com.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland. Electronic address: mcedzynski@cbm.pan.pl.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Copenhagen, Denmark.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.
Publications dans "Lectine liant le mannose" :
2 publications dans cette catégorie
Affiliations :
Department of Biophysics and Radiobiology, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Publications dans "Lectine liant le mannose" :
The human mannose-binding lectin (MBL) gene encodes a polymorphic protein that plays a crucial role in the innate immune response. Human MBL deficiency is associated with immunodeficiencies, and its v...
Complement activation plays a critical role in the pathogenesis of Guillain-Barré syndrome (GBS), a debilitating immune-mediated neuropathy. Mannose-binding lectin (MBL) is a complement activation fac...
Spinal tuberculosis (STB) is a local manifestation of systemic infection caused by Mycobacterium tuberculosis, accounting for a significant proportion of joint tuberculosis cases. This study aimed to ...
124 patients suspected of having STB were collected and divided into STB and non-STB groups according to their pathological diagnosis. Serum MBL levels were measured using ELISA and a Pearson analysis...
The sensitivity of MRI for the diagnosis of STB was 84.38% and specificity was 86.67%. The serum MBL levels of the patients in the STB group were significantly lower than the levels in the non-STB gro...
Both MRI and MBL had certain diagnostic values for STB, but their combined use resulted in a diagnostic accuracy than either one alone....
Atopic dermatitis is a relapsing inflammatory skin condition, in which bacteria, fungi and viruses may colonize the skin and aggravate the condition. Mannose-binding lectin is part of the innate immun...
Mannose-binding lectin (MBL) is a member of innate immunity and acts with MASP (MBL-associated serine protease) to activate the lectin pathway of the complement system. MBL gene polymorphisms are asso...
Pediatric patients diagnosed with COVID-19 by positive real-time polymerase chain reaction (PCR) were included in the study. Single nucleotide polymorphisms in the promoter and exon 1 in the MBL2 gene...
These findings suggest that codon 54 polymorphism in the MBL2 gene exon-1 region can be associated with the symptomatic course of COVID-19....
Mannose-binding lectin (MBL) is an important component of the innate immune system. Polymorphisms in the MBL2 gene and promoter region are directly associated with MBL-deficiency. We sought to determi...
MBL2 gene variants were analyzed in newborns recruited to the GO-CHILD multicenter prospective cohort study. Follow-up for respiratory infection and atopy diagnoses and symptoms, healthcare utilizatio...
Genotyping and follow-up were completed in 1004 children. Genotypes associated with MBL-deficiency were associated with an increased risk of bronchiolitis (relative risk [RR] 1.95, 95% confidence inte...
The positive association between MBL-deficient genotypes and bronchiolitis and pneumonia, as well as a severe wheeze phenotype in some young children, supports the hypothesis that MBL is an important ...
The physiological interactions of MBL suggest its contribution towards the pathogenesis of COPD....
The present case-control study was undertaken to elucidate the role of MBL with COPD risk and clinical outcomes in north Indian cohort....
Patients were enrolled as per GOLD criteria. MBL2 variants were selected based on the literature and their putative functional significance. Genotyping of six single nucleotide polymorphisms of MBL2 c...
Overall findings of the molecular genetic analysis of MBL2 indicated significant difference in frequency of three of the six studied variants, between patients and controls or among different disease ...
The present study reinforces the role played by MBL in the susceptibility, protection and clinical outcomes of COPD. Therefore, including the reported associations at diagnostic, prognostic and therap...
BACKGROUND Sepsis has emerged as a leading cause of death in the intensive care unit. A growing number of studies have shown that genetic variants, especially single nucleotide polymorphisms, are key ...
Premature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory distress. Such adverse effects and the nee...
Cord blood was collected from 535 preterms (born at gestational age ≤37 weeks)....
Low concentrations of CL-10 in cord sera (<462 ng/ml corresponding to the 10...
The complement-activating collectins investigated here could be important for maintaining homeostasis in preterm neonates. Despite similar structure and specificity, MBL, CL-10 and CL-11 manifest a di...
Recurrent aphthous stomatitis is one of the most prevalent oral mucosal immunological diseases. A recent case-control study in the Egyptian population suggested that single nucleotide polymorphism Gly...
The study included 227 subjects; 137 healthy people and 90 patients with recurrent aphthous stomatitis. Six mannose-binding lectin 2 gene polymorphisms (rs11003125, rs7096206, rs7095891, rs5030737, rs...
No significant differences in mean of mannose-binding lectin serum levels between healthy controls and patients with recurrent aphthous stomatitis were observed (383 ng/ml ± 249 standard deviation (SD...
This study did not confirm the previously reported association of the mannose-binding lectin 2 Gly54Asp gene variant and low mannose-binding lectin serum level as the risk factors for susceptibility t...