Les traitements antérieurs augmentent-ils le risque ?
Certains traitements antérieurs pour d'autres cancers peuvent augmenter le risque de ganglioneuroblastome.
Traitements antérieursCancerGanglioneuroblastome
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"name": "Comment diagnostique-t-on un ganglioneuroblastome ?",
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"text": "Le diagnostic se fait par imagerie (IRM, scanner) et biopsie des tissus tumoraux."
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"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer le ganglioneuroblastome ?",
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"@type": "Question",
"name": "Quels symptômes peuvent alerter sur un ganglioneuroblastome ?",
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"name": "Le ganglioneuroblastome peut-il être confondu avec d'autres tumeurs ?",
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"text": "Oui, il peut être confondu avec d'autres tumeurs abdominales ou neuroblastomes."
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"name": "Quels sont les symptômes courants du ganglioneuroblastome ?",
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"@type": "Question",
"name": "Le ganglioneuroblastome provoque-t-il des symptômes neurologiques ?",
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"name": "Le ganglioneuroblastome peut-il causer des symptômes respiratoires ?",
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"@type": "Question",
"name": "Y a-t-il des signes d'alerte précoce pour le ganglioneuroblastome ?",
"position": 10,
"acceptedAnswer": {
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"text": "Des douleurs persistantes, une fatigue excessive et une perte de poids inexpliquée peuvent être des signes d'alerte."
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"@type": "Question",
"name": "Peut-on prévenir le ganglioneuroblastome ?",
"position": 11,
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"@type": "Question",
"name": "Y a-t-il des facteurs de risque identifiés pour le ganglioneuroblastome ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs génétiques peuvent augmenter le risque, mais la plupart des cas sont sporadiques."
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"@type": "Question",
"name": "Les antécédents familiaux influencent-ils le ganglioneuroblastome ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancers peuvent augmenter le risque de ganglioneuroblastome."
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"@type": "Question",
"name": "Les infections peuvent-elles jouer un rôle dans le ganglioneuroblastome ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Aucune preuve solide ne lie les infections au développement du ganglioneuroblastome."
}
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{
"@type": "Question",
"name": "Les habitudes de vie influencent-elles le ganglioneuroblastome ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de lien établi entre les habitudes de vie et le ganglioneuroblastome."
}
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{
"@type": "Question",
"name": "Quels traitements sont disponibles pour le ganglioneuroblastome ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent la chirurgie, la chimiothérapie et parfois la radiothérapie."
}
},
{
"@type": "Question",
"name": "La chirurgie est-elle toujours nécessaire pour traiter le ganglioneuroblastome ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est souvent nécessaire pour retirer la tumeur, mais dépend de sa taille et de son emplacement."
}
},
{
"@type": "Question",
"name": "Quel est le rôle de la chimiothérapie dans le traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chimiothérapie est utilisée pour réduire la taille de la tumeur et traiter les cellules cancéreuses restantes."
}
},
{
"@type": "Question",
"name": "La radiothérapie est-elle couramment utilisée pour le ganglioneuroblastome ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La radiothérapie est parfois utilisée, surtout si la tumeur ne peut pas être complètement retirée par chirurgie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux pour le ganglioneuroblastome ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des traitements expérimentaux comme l'immunothérapie sont en cours d'évaluation."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le ganglioneuroblastome ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la propagation de la tumeur, des douleurs chroniques et des problèmes neurologiques."
}
},
{
"@type": "Question",
"name": "Le ganglioneuroblastome peut-il affecter d'autres organes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut se propager à d'autres organes comme le foie, les poumons ou les os."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications liées à la chimiothérapie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent inclure des nausées, une immunosuppression et des infections."
}
},
{
"@type": "Question",
"name": "Le ganglioneuroblastome peut-il entraîner des problèmes de croissance ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent affecter la croissance et le développement de l'enfant."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive après traitement ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il existe un risque de récidive, surtout si la tumeur n'a pas été complètement retirée."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque du ganglioneuroblastome ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs de risque incluent des anomalies génétiques et des antécédents familiaux de cancers."
}
},
{
"@type": "Question",
"name": "Les enfants de quel âge sont les plus à risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le ganglioneuroblastome touche principalement les enfants de moins de 5 ans."
}
},
{
"@type": "Question",
"name": "Les garçons sont-ils plus à risque que les filles ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le ganglioneuroblastome est légèrement plus fréquent chez les garçons que chez les filles."
}
},
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"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils le ganglioneuroblastome ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Aucune preuve concluante ne lie les facteurs environnementaux au ganglioneuroblastome."
}
},
{
"@type": "Question",
"name": "Les traitements antérieurs augmentent-ils le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains traitements antérieurs pour d'autres cancers peuvent augmenter le risque de ganglioneuroblastome."
}
}
]
}
]
}
Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the AS CR, v. v. i, Prague, Vestec, Czech Republic.
Ganglioneuroblastoma intermixed (GNBI) is classified as "favorable" histology by International Neuroblastoma Pathology Classification system. However, the International Neuroblastoma Risk Group (INRG)...
In this retrospective study, clinical, radiological, pathological, cytogenetic, and molecular information from patients with GNBI at diagnosis seen between 1995 and 2021 was analyzed. INRG staging was...
Of the 15,827 neuroblastoma specimens, GNBI was noted in 237 patients. Of these, 53 had the initial pathological diagnosis of GNBI; median follow-up 3.5 (range: 0.2-14) years. Disease was locoregional...
Localized GNBI at diagnosis has excellent long-term clinical outcome even without cytotoxic therapy. For localized GNBI, a biopsy sample is adequate to make the diagnosis. When associated with metasta...
The authors present an interesting case of ganglioneuroblastoma, a tumor of the sympathetic chain, presenting as severe obstructive sleep apnea in a healthy 5-year-old boy. The patient's initial polys...
Neurofibromatosis type 1 (NF1) is a genetic condition commonly associated with a predisposition to tumor development. Affected individuals have an increased risk of benign and malignant tumors of the ...
To examine the potential of whole-tumor radiomics analysis of T2-weighted imaging (T2WI) in differentiating neuroblastoma (NB) from ganglioneuroblastoma/ganglioneuroma (GNB/GN) in children....
This study included 102 children with peripheral neuroblastic tumors, comprising 47 NB patients and 55 GNB/GN patients, which were randomly divided into a training group (n = 72) and a test group (n =...
Fifteen radiomics features were eventually chosen to construct the optimal radiomics model. The area under the curve (AUC) of the radiomics model in the training group and test group was 0.940 [95% co...
Radiomics features derived from T2WI, in combination with the age of the patient at initial diagnosis, may offer a quantitative method for distinguishing NB from GNB/GN, thus aiding in the pathologica...
Ganglioneuroblastomas (GNBs) are a rare subtype of neoplastic tumors that arise from the autonomic nervous system and contain both mature gangliocytes and immature neuroblasts. The primary age group a...
Ganglioneuroblastoma is a rare peripheral neuroblastic tumor located anywhere in the sympathetic nervous system but rarely in the retropharyngeal space. Diagnosis can often be difficult based on imagi...
Neuroblastomas are the most common extracranial solid malignancy in children with variable manifestations and complications depending on the presence of paraneoplastic syndromes....
We performed a single institution retrospective cohort study of all patients less than 18 years old diagnosed with neuroblastoma or ganglioneuroblastoma between January 2002 and July 2022. Patients we...
In our study period, 130 children were diagnosed with neuroblastoma, and 15 were diagnosed with ganglioneuroblastoma. There were 12 children with a paraneoplastic syndrome identified, 8 with NBL and 4...
The histological profile of paraneoplastic syndromes of neuroblastoma and ganglioneuroblastoma and their treatment across a single institution can be highly variable. The presence of tumor-infiltratin...
To identify radiomic features that can predict the pathological type of neuroblastic tumor in children....
Data on neuroblastic tumors in 104 children were retrospectively analyzed. There were 14 cases of ganglioneuroma, 24 cases of ganglioneuroblastoma, and 65 cases of neuroblastoma. Stratified sampling w...
Based on 10 clinical-radiomic features, the classifier identified ganglioneuroma compared to the other two tumor types in the validation dataset with sensitivity of 100.0%, specificity of 81.8%, and a...
Radiomic features can help predict the pathological type of neuroblastic tumors in children....
Peripheral neuroblastic tumors represent the fourth-largest group of malignant tumors in childhood. The majority of these tumors are neuroblastomas, which can be classified into undifferentiated, poor...