Recherchemedicale.com
Maladies de l'appareil digestif
Maladie des voies biliaires
Maladies des canaux biliaires
Cholestase
Cholestase : Questions médicales fréquentes
Diagnostic
5
Cholestase
Biopsie hépatique
Bilirubine
Tests sanguins
Échographie
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Biopsie hépatique
Cholestase
Symptômes
5
Démangeaisons
Sels biliaires
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Cholestase
Malnutrition
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5
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Maladies hépatiques
Alimentation
Santé hépatique
Contrôle du poids
Maladies hépatiques
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5
Acide ursodéoxycholique
Médicaments
Chirurgie
Obstruction des voies biliaires
Régime alimentaire
Cholestase
Suppléments
Vitamines liposolubles
Complications
5
Cirrhose
Insuffisance hépatique
Infections
Voies biliaires
Insuffisance hépatique
Cholestase
Facteurs de risque
5
Obésité
Maladies hépatiques
Cholestase gravidique
Femmes
Maladies auto-immunes
Cholangite sclérosante
Tabagisme
Maladies hépatiques
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"@type": "Question",
"name": "Quels tests sanguins sont utilisés ?",
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"@type": "Question",
"name": "L'échographie est-elle utile ?",
"position": 3,
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"name": "Quand faire une biopsie hépatique ?",
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"@type": "Question",
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"@type": "Question",
"name": "Quels sont les symptômes de la cholestase ?",
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"@type": "Question",
"name": "La cholestase cause-t-elle des démangeaisons ?",
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"@type": "Question",
"name": "Peut-on avoir des douleurs abdominales ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, des douleurs dans la partie supérieure droite de l'abdomen peuvent survenir."
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"name": "La fatigue est-elle un symptôme ?",
"position": 9,
"acceptedAnswer": {
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"text": "Oui, la fatigue est fréquente en raison de l'accumulation de toxines dans le sang."
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{
"@type": "Question",
"name": "Y a-t-il des signes de malnutrition ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, une malabsorption des graisses peut entraîner des carences nutritionnelles."
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"name": "Comment prévenir la cholestase ?",
"position": 11,
"acceptedAnswer": {
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"text": "Prévenir les maladies hépatiques et maintenir un mode de vie sain aide à réduire le risque."
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{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée et riche en fibres peut soutenir la santé hépatique."
}
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{
"@type": "Question",
"name": "Faut-il éviter certains médicaments ?",
"position": 13,
"acceptedAnswer": {
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"text": "Oui, certains médicaments peuvent aggraver la cholestase, consultez un médecin."
}
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"@type": "Question",
"name": "Les examens réguliers sont-ils importants ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, des examens réguliers du foie peuvent aider à détecter des problèmes précocement."
}
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{
"@type": "Question",
"name": "Le contrôle du poids est-il essentiel ?",
"position": 15,
"acceptedAnswer": {
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"name": "Quels traitements existent pour la cholestase ?",
"position": 16,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des médicaments comme l'acide ursodéoxycholique peuvent améliorer l'écoulement biliaire."
}
},
{
"@type": "Question",
"name": "Quand envisager une intervention chirurgicale ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est envisagée en cas d'obstruction des voies biliaires ou de lésions hépatiques."
}
},
{
"@type": "Question",
"name": "Un régime alimentaire peut-il aider ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un régime pauvre en graisses peut réduire les symptômes et améliorer la digestion."
}
},
{
"@type": "Question",
"name": "Des suppléments sont-ils recommandés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des suppléments de vitamines liposolubles peuvent être nécessaires en cas de malabsorption."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la cirrhose, l'insuffisance hépatique et des infections."
}
},
{
"@type": "Question",
"name": "La cholestase peut-elle causer des infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'accumulation de bile peut favoriser des infections des voies biliaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de cirrhose ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une cholestase prolongée peut entraîner une cirrhose et des dommages hépatiques irréversibles."
}
},
{
"@type": "Question",
"name": "L'insuffisance hépatique est-elle possible ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une cholestase sévère peut conduire à une insuffisance hépatique aiguë ou chronique."
}
},
{
"@type": "Question",
"name": "Des problèmes de coagulation peuvent-ils survenir ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la cholestase peut affecter la production de facteurs de coagulation, augmentant le risque de saignement."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de cholestase ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'obésité, l'alcoolisme, et certaines maladies hépatiques."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque de cholestase augmente avec l'âge, surtout chez les personnes âgées."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines formes de cholestase, comme la cholestase gravidique, touchent plus les femmes."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme la cholangite sclérosante peuvent augmenter le risque de cholestase."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut aggraver les maladies hépatiques et augmenter le risque de cholestase."
}
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]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 24/12/2024
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of In Vitro Toxicology & Dermato-Cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, 1090, Belgium.
Publications dans "Cholestase" :
4 publications dans cette catégorie
Affiliations :
Department of In Vitro Toxicology & Dermato-Cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, 1090, Belgium.
Publications dans "Cholestase" :
3 publications dans cette catégorie
Affiliations :
Drug Delivery & Disposition, Department of Pharmaceutical & Pharmacological Sciences, Katholieke Universiteit Leuven, ON II Herestraat 49, Box 921, Leuven, 3000, Belgium.
Publications dans "Cholestase" :
3 publications dans cette catégorie
Affiliations :
Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty at Heinrich-Heine-University, Düsseldorf, Germany. Verena.Keitel@med.uni-duesseldorf.de.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of In Vitro Toxicology & Dermato-Cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, 1090, Belgium.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, School of Veterinary Medicine & Animal Science, University of São Paulo, Av. Prof. Dr. Orlando Marques de Paiva 87, Cidade Universitária, SP, 05508-270, Brazil.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Basic & Applied Medical Sciences, Gut-Liver Immunopharmacology Unit, Faculty of Medicine & Health Sciences, Ghent University, C Heymanslaan 10, Ghent, 9000, Belgium.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Internal Medicine Unit for the Treatment of Severe Organ Failure, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
European Reference Network on Hepatological Diseases (ERN RARE-LIVER), 20246 Hamburg, Germany.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai 201102, China.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai 201102, China.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Amsterdam University Medical Centers, Tytgat Institute for Liver and Intestinal Research, Research Institute Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), University of Amsterdam, Amsterdam, Netherlands.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Digestive Health Institute, Children's Hospital Colorado, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, Aurora, CO.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Digestive Health Institute, Children's Hospital Colorado, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, Aurora, CO.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Division of Gastroenterology, Hepatology, and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, United States. james.squires2@chp.edu.
Publications dans "Cholestase" :
2 publications dans cette catégorie
Affiliations :
Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands. u.h.beuers@amsterdamumc.nl.
Publications dans "Cholestase" :
Idiosyncratic Drug-Induced Liver Injury (iDILI) represents an actual health challenge, accounting for more than 40% of hepatitis cases in adults over 50 years and more than 50% of acute fulminant hepa...
Cholestasis is characterized by a conjugated hyperbilirubinemia secondary to impaired bile synthesis, transport, or excretion from the liver. It is always pathologic and can be indicative of an underl...
Increased accessibility of next generation sequencing (NGS) allows for utilization of genetic testing early in the diagnostic process. This may alter the clinical algorithm for diagnosis of cholestati...
To describe the incidence and to analyze risk factors associated with cholestasis in neonates with gastroschisis....
This is a retrospective cohort study in a tertiary single center analyzing 181 newborns with gastroschisis between 2009 and 2020. The following risk factors associated with cholestasis were analyzed: ...
Among the 176 patients evaluated, 41 (23.3%) evolved with cholestasis. In the univariate analysis, low birth weight (p=0.023), prematurity (p<0.001), lipid emulsion with medium-chain triglycerides and...
Our study shows that lipid emulsion with fish oil is associated with a lower risk of cholestasis in neonates with gastroschisis. However, this is a retrospective study and a prospective study should b...
Jaundice within the first 1-2 weeks of a neonate's life will generally self-resolve; however, if it lasts longer than this time frame it warrants further work up. Direct or conjugated hyperbilirubinem...
We describe an infant who presented with neonatal cholestasis. He subsequently underwent work up for biliary atresia, as this is one of the more time-sensitive diagnoses that must be made in neonates ...
We found that conservative management, specifically optimizing nutrition and treating with ursodeoxycholic acid, can be a sufficient approach to facilitating resolution of the choledocholithiasis and ...
Pruritus in cholestatic liver diseases can be a major burden and dramatically impair the quality of life of those affected. Here, we provide an update on the latest insights into the molecular pathoge...
Malnutrition in children with chronic cholestasis is a prevalent issue and a major risk factor for adverse outcomes. Fat soluble vitamin (FSV) deficiency is an integral feature of cholestatic disease ...
Alagille syndrome and progressive familial intrahepatic cholestasis are conditions that can affect multiple organs. Advancements in molecular testing have aided in the diagnosis of both. The impairmen...
Cholestasis and obstructive jaundice can be caused by several factors. Kuraoka et al. report an extremely rare case of cholestasis due to occlusion of the distal bile duct by an inferior vena cava fil...
Vitamin D deficiency in patients with cholestasis is due to impaired intestinal vitamin D absorption, which results from decreased intestinal bile acid concentration. Patients with cholestasis usually...
This study is a prospective study that included pediatric patients with cholestasis (serum direct bilirubin > 1 mg/dL) who had vitamin D deficiency (serum 25-hydroxyvitamin D, 25-OHD, < 20 ng/mL). In ...
Phase 1: Seven patients were enrolled. Three out of seven patients had a moderate increase in serum 25-OHD after loading (up to 20.3-27.2 ng/mL). These patients had conditions with partially preserved...
Very high doses of vitamin D2 (200,000 and 400,000 IU/day) partly overcame poor intestinal vitamin D absorption and resulted in moderate increases in serum 25-OHD in pediatric patients with cholestasi...
Infantile cholestasis (IC) is the most common hepatobiliary disease in infants, resulting in elevated direct bilirubin levels. Indeed, hepatointestinal circulation impacts bile acid and bilirubin meta...
The gut microbiota in the IC group exhibits the higher abundance of Veillonella, Streptococcus and Clostridium spp. (P < 0.05), compared to healthy infants (CON) group. Moreover, the abundance of Rumi...
Microbiota dysbiosis happened in IC children, which also can lead to the abnormal metabolism, thus obstructing the absorption of enteral nutrition and aggravating liver cell damage. Veillonella, Rumin...