Zdzislaw Wawrzak

Affiliations

Synchrotron Research Center, LS-CAT, Sector 21, Northwestern University, Lemont, Illinois 60439, United States.

Publications (18)

A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid.

Journal of the American Chemical Society

Avec: Wei Zhu , Peter F Doubleday , Daniel S Catlin , Pathum M Weerawarna , Arseniy Butrin , Sida Shen , Zdzislaw Wawrzak , Neil L Kelleher , Dali Liu , Richard B Silverman

The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch.

Nature structural & molecular biology

Avec: Amanda L Photenhauer , Rosendo C Villafuerte-Vega , Filipe M Cerqueira , Krista M Armbruster , Filip Mareček , Tiantian Chen , Zdzislaw Wawrzak , Jesse B Hopkins , Craig W Vander Kooi , Štefan Janeček , Brandon T Ruotolo , Nicole M Koropatkin

A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis.

The Journal of biological chemistry

Avec: Tatiana Y Hargrove , Zdzislaw Wawrzak , F Peter Guengerich , Galina I Lepesheva

The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil.

Biochemistry

Avec: Dariush C Forouzesh , Brett A Beaupre , Arseniy Butrin , Zdzislaw Wawrzak , Dali Liu , Graham R Moran

De Novo Design of a Self-Assembled Artificial Copper Peptide that Activates and Reduces Peroxide.

ACS catalysis

Avec: Suchitra Mitra , Divyansh Prakash , Khashayar Rajabimoghadam , Zdzislaw Wawrzak , Pallavi Prasad , Tong Wu , Sandeep K Misra , Joshua S Sharp , Isaac Garcia-Bosch , Saumen Chakraborty

Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from

The Journal of biological chemistry

Avec: Heidi L Doden , Rebecca M Pollet , Sean M Mythen , Zdzislaw Wawrzak , Saravanan Devendran , Isaac Cann , Nicole M Koropatkin , Jason M Ridlon

Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome.

The Journal of biological chemistry

Avec: Filipe M Cerqueira , Amanda L Photenhauer , Heidi L Doden , Aric N Brown , Ahmed M Abdel-Hamid , Sarah Moraïs , Edward A Bayer , Zdzislaw Wawrzak , Isaac Cann , Jason M Ridlon , Jesse B Hopkins , Nicole M Koropatkin

A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.

Microbiology resource announcements

Avec: Nicole L Inniss , Travis J Kochan , George Minasov , Zdzislaw Wawrzak , Changsoo Chang , Kemin Tan , Ludmilla Shuvalova , Olga Kiryukhina , Sergii Pshenychnyi , Ruiying Wu , Ivegeniia Dubrovska , Gyorgy Babnigg , Michael Endres , Wayne F Anderson , Alan R Hauser , Andrzej Joachimiak , Karla J F Satchell

BoGH13A

Cellular and molecular life sciences : CMLS

Avec: Haley A Brown , Anna L DeVeaux , Brock R Juliano , Amanda L Photenhauer , Matthieu Boulinguiez , Russell E Bornschein , Zdzislaw Wawrzak , Brandon T Ruotolo , Nicolas Terrapon , Nicole M Koropatkin

Validation of Human Sterol 14α-Demethylase (CYP51) Druggability: Structure-Guided Design, Synthesis, and Evaluation of Stoichiometric, Functionally Irreversible Inhibitors.

Journal of medicinal chemistry

Avec: Laura Friggeri , Tatiana Y Hargrove , Zdzislaw Wawrzak , F Peter Guengerich , Galina I Lepesheva

Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase.

The Journal of biological chemistry

Avec: Arseniy Butrin , Anastassiya Butrin , Zdzislaw Wawrzak , Graham R Moran , Dali Liu

Structural and dynamic features of Acinetobacter baumannii OXA-66 β-lactamase explain its stability and evolution of novel variants.

Journal of molecular biology

Avec: Zachary L Klamer , Cynthia M June , Zdzislaw Wawrzak , Magdalena A Taracila , Joshua A Grey , Alyssa M I Benn , Christopher P Russell , Robert A Bonomo , Rachel A Powers , David A Leonard , Agnieszka Szarecka

Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics.

Scientific reports

Avec: Tatiana Y Hargrove , David C Lamb , Jarrod A Smith , Zdzislaw Wawrzak , Steven L Kelly , Galina I Lepesheva

Structure of galactarate dehydratase, a new fold in an enolase involved in bacterial fitness after antibiotic treatment.

Protein science : a publication of the Protein Society

Avec: Monica Rosas-Lemus , George Minasov , Ludmilla Shuvalova , Zdzislaw Wawrzak , Olga Kiryukhina , Nathan Mih , Lukasz Jaroszewski , Bernhard Palsson , Adam Godzik , Karla J F Satchell

Cytochrome

The Journal of biological chemistry

Avec: Julius Campeciño , Satyanarayana Lagishetty , Zdzislaw Wawrzak , Victor Sosa Alfaro , Nicolai Lehnert , Gemma Reguera , Jian Hu , Eric L Hegg

Degradation of complex arabinoxylans by human colonic Bacteroidetes.

Nature communications

Avec: Gabriel V Pereira , Ahmed M Abdel-Hamid , Soumajit Dutta , Corina N D'Alessandro-Gabazza , Daniel Wefers , Jacob A Farris , Shiv Bajaj , Zdzislaw Wawrzak , Haruyuki Atomi , Roderick I Mackie , Esteban C Gabazza , Diwakar Shukla , Nicole M Koropatkin , Isaac Cann

Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.

Molecular biology and evolution

Avec: David C Lamb , Tatiana Y Hargrove , Bin Zhao , Zdzislaw Wawrzak , Jared V Goldstone , William David Nes , Steven L Kelly , Michael R Waterman , John J Stegeman , Galina I Lepesheva

Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation.

Nature communications

Avec: Barbara A Bensing , Haley E Stubbs , Rupesh Agarwal , Izumi Yamakawa , Kelvin Luong , Kemal Solakyildirim , Hai Yu , Azadeh Hadadianpour , Manuel A Castro , Kevin P Fialkowski , KeAndreya M Morrison , Zdzislaw Wawrzak , Xi Chen , Carlito B Lebrilla , Jerome Baudry , Jeremy C Smith , Paul M Sullam , T M Iverson

Réseau de co-auteurs

Nicole M Koropatkin 5 collaborations

Tatiana Y Hargrove 4 collaborations

Galina I Lepesheva 4 collaborations

Arseniy Butrin 3 collaborations

Dali Liu 3 collaborations

Amanda L Photenhauer 3 collaborations

Isaac Cann 3 collaborations

Filipe M Cerqueira 2 collaborations

Jesse B Hopkins 2 collaborations

Brandon T Ruotolo 2 collaborations

F Peter Guengerich 2 collaborations

Graham R Moran 2 collaborations

Heidi L Doden 2 collaborations

Jason M Ridlon 2 collaborations

Ahmed M Abdel-Hamid 2 collaborations

George Minasov 2 collaborations

Ludmilla Shuvalova 2 collaborations

Olga Kiryukhina 2 collaborations

Karla J F Satchell 2 collaborations

David C Lamb 2 collaborations

Steven L Kelly 2 collaborations

Wei Zhu 1 collaboration

Peter F Doubleday 1 collaboration

Daniel S Catlin 1 collaboration

Pathum M Weerawarna 1 collaboration

Sida Shen 1 collaboration

Neil L Kelleher 1 collaboration

Richard B Silverman 1 collaboration

Rosendo C Villafuerte-Vega 1 collaboration

Krista M Armbruster 1 collaboration

Filip Mareček 1 collaboration

Tiantian Chen 1 collaboration

Craig W Vander Kooi 1 collaboration

Štefan Janeček 1 collaboration

Dariush C Forouzesh 1 collaboration

Brett A Beaupre 1 collaboration

Suchitra Mitra 1 collaboration

Divyansh Prakash 1 collaboration

Khashayar Rajabimoghadam 1 collaboration

Pallavi Prasad 1 collaboration

Tong Wu 1 collaboration

Sandeep K Misra 1 collaboration

Joshua S Sharp 1 collaboration

Isaac Garcia-Bosch 1 collaboration

Saumen Chakraborty 1 collaboration

Rebecca M Pollet 1 collaboration

Sean M Mythen 1 collaboration

Saravanan Devendran 1 collaboration

Aric N Brown 1 collaboration

Sarah Moraïs 1 collaboration

Edward A Bayer 1 collaboration

Nicole L Inniss 1 collaboration

Travis J Kochan 1 collaboration

Changsoo Chang 1 collaboration

Kemin Tan 1 collaboration

Sergii Pshenychnyi 1 collaboration

Ruiying Wu 1 collaboration

Ivegeniia Dubrovska 1 collaboration

Gyorgy Babnigg 1 collaboration

Michael Endres 1 collaboration

Wayne F Anderson 1 collaboration

Alan R Hauser 1 collaboration

Andrzej Joachimiak 1 collaboration

Haley A Brown 1 collaboration

Anna L DeVeaux 1 collaboration

Brock R Juliano 1 collaboration

Matthieu Boulinguiez 1 collaboration

Russell E Bornschein 1 collaboration

Nicolas Terrapon 1 collaboration

Laura Friggeri 1 collaboration

Anastassiya Butrin 1 collaboration

Zachary L Klamer 1 collaboration

Cynthia M June 1 collaboration

Magdalena A Taracila 1 collaboration

Joshua A Grey 1 collaboration

Alyssa M I Benn 1 collaboration

Christopher P Russell 1 collaboration

Robert A Bonomo 1 collaboration

Rachel A Powers 1 collaboration

David A Leonard 1 collaboration

Agnieszka Szarecka 1 collaboration

Jarrod A Smith 1 collaboration

Monica Rosas-Lemus 1 collaboration

Nathan Mih 1 collaboration

Lukasz Jaroszewski 1 collaboration

Bernhard Palsson 1 collaboration

Adam Godzik 1 collaboration

Julius Campeciño 1 collaboration

Satyanarayana Lagishetty 1 collaboration

Victor Sosa Alfaro 1 collaboration

Nicolai Lehnert 1 collaboration

Gemma Reguera 1 collaboration

Jian Hu 1 collaboration

Eric L Hegg 1 collaboration

Gabriel V Pereira 1 collaboration

Soumajit Dutta 1 collaboration

Corina N D'Alessandro-Gabazza 1 collaboration

Daniel Wefers 1 collaboration

Jacob A Farris 1 collaboration

Shiv Bajaj 1 collaboration

Haruyuki Atomi 1 collaboration

Roderick I Mackie 1 collaboration

Esteban C Gabazza 1 collaboration

Diwakar Shukla 1 collaboration

Bin Zhao 1 collaboration

Jared V Goldstone 1 collaboration

William David Nes 1 collaboration

Michael R Waterman 1 collaboration

John J Stegeman 1 collaboration

Barbara A Bensing 1 collaboration

Haley E Stubbs 1 collaboration

Rupesh Agarwal 1 collaboration

Izumi Yamakawa 1 collaboration

Kelvin Luong 1 collaboration

Kemal Solakyildirim 1 collaboration

Hai Yu 1 collaboration

Azadeh Hadadianpour 1 collaboration

Manuel A Castro 1 collaboration

Kevin P Fialkowski 1 collaboration

KeAndreya M Morrison 1 collaboration

Xi Chen 1 collaboration

Carlito B Lebrilla 1 collaboration

Jerome Baudry 1 collaboration

Jeremy C Smith 1 collaboration

Paul M Sullam 1 collaboration

T M Iverson 1 collaboration