Yvonne M W Janssen-Heininger

Affiliations

Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont, USA.

Publications (22)

Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Yoshimitsu Yura , Brian S H Chong , Ryan D Johnson , Yosuke Watanabe , Yuko Tsukahara , Beatriz Ferran , Colin E Murdoch , Jessica B Behring , Mark E McComb , Catherine E Costello , Yvonne M W Janssen-Heininger , Richard A Cohen , Markus M Bachschmid , Reiko Matsui

Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.

American journal of respiratory cell and molecular biology

Avec: Allison M Manuel , Cheryl van de Wetering , Maximilian MacPherson , Cuixia Erickson , Caliann Murray , Reem Aboushousha , Jos van der Velden , Anne E Dixon , Matthew E Poynter , Charles G Irvin , Douglas J Taatjes , Albert van der Vliet , Vikas Anathy , Yvonne M W Janssen-Heininger

Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease.

Mucosal immunology

Avec: Carolyn R Morris , Aida Habibovic , Christopher M Dustin , Caspar Schiffers , Miao-Chong Lin , Jennifer L Ather , Yvonne M W Janssen-Heininger , Matthew E Poynter , Olaf Utermohlen , Martin Krönke , Albert van der Vliet

Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation.

American journal of physiology. Lung cellular and molecular physiology

Avec: Aida Habibovic , Milena Hristova , Carolyn R Morris , Miao-Chong Joy Lin , Litiele C Cruz , Jennifer L Ather , Miklós Geiszt , Vikas Anathy , Yvonne M W Janssen-Heininger , Matthew E Poynter , Anne E Dixon , Albert van der Vliet

Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models.

PloS one

Avec: Jos L van der Velden , John F Alcorn , David G Chapman , Lennart K A Lundblad , Charles G Irvin , Roger J Davis , Kelly Butnor , Yvonne M W Janssen-Heininger

The Effect of Flavored E-cigarettes on Murine Allergic Airways Disease.

Scientific reports

Avec: David G Chapman , Dylan T Casey , Jennifer L Ather , Minara Aliyeva , Nirav Daphtary , Karolyn G Lahue , Jos L van der Velden , Yvonne M W Janssen-Heininger , Charles G Irvin

Local fractal dimension of collagen detects increased spatial complexity in fibrosis.

Histochemistry and cell biology

Avec: Dylan T Casey , Karolyn G Lahue , Vitor Mori , Jacob Herrmann , Joseph K Hall , Béla Suki , Yvonne M W Janssen-Heininger , Jason H T Bates

The glutathione S-transferase Gstt1 drives survival and dissemination in metastases.

Nature cell biology

Avec: Christina M Ferrer , Hyo Min Cho , Ruben Boon , Tiziano Bernasocchi , Lai Ping Wong , Murat Cetinbas , Elizabeth R Haggerty , Irene Mitsiades , Gregory R Wojtkiewicz , Daniel E McLoughlin , Reem Aboushousha , Hend Abdelhamid , Sita Kugel , Esther Rheinbay , Ruslan Sadreyev , Dejan Juric , Yvonne M W Janssen-Heininger , Raul Mostoslavsky

Dysregulation of the glutaredoxin/

American journal of physiology. Cell physiology

Avec: Shi B Chia , Evan A Elko , Reem Aboushousha , Allison M Manuel , Cheryl van de Wetering , Joseph E Druso , Jos van der Velden , David J Seward , Vikas Anathy , Charles G Irvin , Ying-Wai Lam , Albert van der Vliet , Yvonne M W Janssen-Heininger

Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema.

American journal of physiology. Lung cellular and molecular physiology

Avec: Caspar Schiffers , Lennart K A Lundblad , Milena Hristova , Aida Habibovic , Christopher M Dustin , Nirav Daphtary , Minara Aliyeva , David J Seward , Yvonne M W Janssen-Heininger , Emiel F M Wouters , Niki L Reynaert , Albert van der Vliet

Oxidation of peroxiredoxin-4 induces oligomerization and promotes interaction with proteins governing protein folding and endoplasmic reticulum stress.

The Journal of biological chemistry

Avec: Evan A Elko , Allison M Manuel , Sheryl White , Ester Zito , Albert van der Vliet , Vikas Anathy , Yvonne M W Janssen-Heininger

Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?

Redox biology

Avec: Cheryl van de Wetering , Evan Elko , Marijn Berg , Caspar H J Schiffers , Vasili Stylianidis , Maarten van den Berge , Martijn C Nawijn , Emiel F M Wouters , Yvonne M W Janssen-Heininger , Niki L Reynaert

Fingerprint of the oxido-reductase ERO1: A protein disulfide bond producer and supporter of cancer.

Biochimica et biophysica acta. Reviews on cancer

Avec: Ester Zito , Luca Guarrera , Yvonne M W Janssen-Heininger

Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Cheryl van de Wetering , Reem Aboushousha , Allison M Manuel , Shi B Chia , Cuixia Erickson , Maximilian B MacPherson , Jos L van der Velden , Vikas Anathy , Anne E Dixon , Charles G Irvin , Matthew E Poynter , Albert van der Vliet , Emiel F M Wouters , Niki L Reynaert , Yvonne M W Janssen-Heininger

The protein disulfide isomerase A3 and osteopontin axis promotes influenza-induced lung remodelling.

British journal of pharmacology

Avec: Amit Kumar , Zoe F Mark , Morgan P Carbajal , Dhemerson Souza DeLima , Nicolas Chamberlain , Joseph Walzer , Mona Ruban , Ravishankar Chandrasekaran , Nirav Daphtary , Minara Aliyeva , Matthew E Poynter , Yvonne M W Janssen-Heininger , Jason H Bates , John F Alcorn , Clemente J Britto , Charles S Dela Cruz , Anil G Jegga , Vikas Anathy

Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility.

Nature communications

Avec: Elizabeth M Corteselli , Mona Sharafi , Robert Hondal , Maximilian MacPherson , Sheryl White , Ying-Wai Lam , Clarissa Gold , Allison M Manuel , Albert van der Vliet , Severin T Schneebeli , Vikas Anathy , Jianing Li , Yvonne M W Janssen-Heininger

Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system x

Science advances

Avec: Reem Aboushousha , Jos van der Velden , Nicholas Hamilton , Zhihua Peng , Maximilian MacPherson , Cuixia Erickson , Sheryl White , Emiel F M Wouters , Niki L Reynaert , David J Seward , Jianing Li , Yvonne M W Janssen-Heininger

Age-dependent dysregulation of redox genes may contribute to fibrotic pulmonary disease susceptibility.

Free radical biology & medicine

Avec: Evan A Elko , J Matthew Mahoney , Pamela Vacek , Albert van der Vliet , Vikas Anathy , Jos L J L van der Velden , Yvonne M W Janssen-Heininger , David J Seward

Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Reem Aboushousha , Evan Elko , Shi B Chia , Allison M Manuel , Cheryl van de Wetering , Jos van der Velden , Maximilian MacPherson , Cuixia Erickson , Julie A Reisz , Angelo D'Alessandro , Emiel F M Wouters , Niki L Reynaert , Ying-Wai Lam , Vikas Anathy , Albert van der Vliet , David J Seward , Yvonne M W Janssen-Heininger

Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling.

Redox biology

Avec: Shi B Chia , James D Nolin , Reem Aboushousha , Cuixia Erikson , Charles G Irvin , Matthew E Poynter , Jos van der Velden , Douglas J Taatjes , Albert van der Vliet , Vikas Anathy , Yvonne M W Janssen-Heininger

Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissues.

Redox biology

Avec: Litiele Cezar Cruz , Aida Habibovic , Bianca Dempsey , Mariana P Massafera , Yvonne M W Janssen-Heininger , Miao-Chong Joy Lin , Evan T Hoffman , Daniel J Weiss , Steven K Huang , Albert van der Vliet , Flavia C Meotti

ER Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation.

American journal of respiratory cell and molecular biology

Avec: Joseph E Druso , Maximilian B MacPherson , Shi B Chia , Evan Elko , Reem Aboushousha , David J Seward , Hend Abdelhamid , Cuixia Erickson , Elizabeth Corteselli , Megan Tarte , Zhihua Peng , Daniel Bernier , Ester Zito , Matthew D Shoulders , Victor J Thannickal , Steven Huang , Albert van der Vliet , Vikas Anathy , Yvonne M W Janssen-Heininger

Réseau de co-auteurs

Albert van der Vliet 13 collaborations

Vikas Anathy 11 collaborations

Reem Aboushousha 8 collaborations

Allison M Manuel 6 collaborations

Matthew E Poynter 6 collaborations

Charles G Irvin 6 collaborations

David J Seward 6 collaborations

Cheryl van de Wetering 5 collaborations

Cuixia Erickson 5 collaborations

Jos van der Velden 5 collaborations

Shi B Chia 5 collaborations

Emiel F M Wouters 5 collaborations

Niki L Reynaert 5 collaborations

Maximilian MacPherson 4 collaborations

Aida Habibovic 4 collaborations

Anne E Dixon 3 collaborations

Jennifer L Ather 3 collaborations

Jos L van der Velden 3 collaborations

Minara Aliyeva 3 collaborations

Nirav Daphtary 3 collaborations

Evan A Elko 3 collaborations

Ying-Wai Lam 3 collaborations

Sheryl White 3 collaborations

Ester Zito 3 collaborations

Evan Elko 3 collaborations

Douglas J Taatjes 2 collaborations

Carolyn R Morris 2 collaborations

Christopher M Dustin 2 collaborations

Caspar Schiffers 2 collaborations

Milena Hristova 2 collaborations

Miao-Chong Joy Lin 2 collaborations

John F Alcorn 2 collaborations

David G Chapman 2 collaborations

Lennart K A Lundblad 2 collaborations

Dylan T Casey 2 collaborations

Karolyn G Lahue 2 collaborations

Hend Abdelhamid 2 collaborations

Joseph E Druso 2 collaborations

Maximilian B MacPherson 2 collaborations

Jianing Li 2 collaborations

Zhihua Peng 2 collaborations

Yoshimitsu Yura 1 collaboration

Brian S H Chong 1 collaboration

Ryan D Johnson 1 collaboration

Yosuke Watanabe 1 collaboration

Yuko Tsukahara 1 collaboration

Beatriz Ferran 1 collaboration

Colin E Murdoch 1 collaboration

Jessica B Behring 1 collaboration

Mark E McComb 1 collaboration

Catherine E Costello 1 collaboration

Richard A Cohen 1 collaboration

Markus M Bachschmid 1 collaboration

Reiko Matsui 1 collaboration

Caliann Murray 1 collaboration

Miao-Chong Lin 1 collaboration

Olaf Utermohlen 1 collaboration

Martin Krönke 1 collaboration

Litiele C Cruz 1 collaboration

Miklós Geiszt 1 collaboration

Roger J Davis 1 collaboration

Kelly Butnor 1 collaboration

Vitor Mori 1 collaboration

Jacob Herrmann 1 collaboration

Joseph K Hall 1 collaboration

Béla Suki 1 collaboration

Jason H T Bates 1 collaboration

Christina M Ferrer 1 collaboration

Hyo Min Cho 1 collaboration

Ruben Boon 1 collaboration

Tiziano Bernasocchi 1 collaboration

Lai Ping Wong 1 collaboration

Murat Cetinbas 1 collaboration

Elizabeth R Haggerty 1 collaboration

Irene Mitsiades 1 collaboration

Gregory R Wojtkiewicz 1 collaboration

Daniel E McLoughlin 1 collaboration

Sita Kugel 1 collaboration

Esther Rheinbay 1 collaboration

Ruslan Sadreyev 1 collaboration

Dejan Juric 1 collaboration

Raul Mostoslavsky 1 collaboration

Marijn Berg 1 collaboration

Caspar H J Schiffers 1 collaboration

Vasili Stylianidis 1 collaboration

Maarten van den Berge 1 collaboration

Martijn C Nawijn 1 collaboration

Luca Guarrera 1 collaboration

Amit Kumar 1 collaboration

Zoe F Mark 1 collaboration

Morgan P Carbajal 1 collaboration

Dhemerson Souza DeLima 1 collaboration

Nicolas Chamberlain 1 collaboration

Joseph Walzer 1 collaboration

Mona Ruban 1 collaboration

Ravishankar Chandrasekaran 1 collaboration

Jason H Bates 1 collaboration

Clemente J Britto 1 collaboration

Charles S Dela Cruz 1 collaboration

Anil G Jegga 1 collaboration

Elizabeth M Corteselli 1 collaboration

Mona Sharafi 1 collaboration

Robert Hondal 1 collaboration

Clarissa Gold 1 collaboration

Severin T Schneebeli 1 collaboration

Nicholas Hamilton 1 collaboration

J Matthew Mahoney 1 collaboration

Pamela Vacek 1 collaboration

Jos L J L van der Velden 1 collaboration

Julie A Reisz 1 collaboration

Angelo D'Alessandro 1 collaboration

James D Nolin 1 collaboration

Cuixia Erikson 1 collaboration

Litiele Cezar Cruz 1 collaboration

Bianca Dempsey 1 collaboration

Mariana P Massafera 1 collaboration

Evan T Hoffman 1 collaboration

Daniel J Weiss 1 collaboration

Steven K Huang 1 collaboration

Flavia C Meotti 1 collaboration

Elizabeth Corteselli 1 collaboration

Megan Tarte 1 collaboration

Daniel Bernier 1 collaboration

Matthew D Shoulders 1 collaboration

Victor J Thannickal 1 collaboration

Steven Huang 1 collaboration