Yoshio Goshima

Affiliations

Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, Yokohama, 236-0004, Japan.

Publications (26)

Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury.

Scientific reports

Avec: Shunsuke Kondo , Kazuya Takahashi , Yuki Kinoshita , Jun Nagai , Shuji Wakatsuki , Toshiyuki Araki , Yoshio Goshima , Toshio Ohshima

Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation.

Journal of the neurological sciences

Avec: Kentaro Togashi , Masaya Hasegawa , Jun Nagai , Ken Kotaka , Arina Yazawa , Miyuki Takahashi , Daiki Masukawa , Yoshio Goshima , Kenneth Hensley , Toshio Ohshima

Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones

Frontiers in neural circuits

Avec: Masaru Takabatake , Yoshio Goshima , Yukio Sasaki

A mathematical model for dynamics of soluble form of DNAM-1 as a biomarker for graft-versus-host disease.

PloS one

Avec: Yuki Goshima , Shinji Nakaoka , Kazuteru Ohashi , Hisashi Sakamaki , Kazuko Shibuya , Akira Shibuya

Low Incidence of High-Grade Pancreatic Intraepithelial Neoplasia Lesions in a Crmp4 Gene-Deficient Mouse Model of Pancreatic Cancer.

Translational oncology

Avec: Keiichi Yazawa , Fumio Nakamura , Daiki Masukawa , Sho Sato , Yukihiko Hiroshima , Yasuhiro Yabushita , Ryutaro Mori , Ryusei Matsuyama , Ikuma Kato , Hideki Taniguchi , Yoshio Goshima , Itaru Endo

Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor.

Journal of pharmacological sciences

Avec: Masayuki Nakano , Motokazu Koga , Tatsuo Hashimoto , Natsuki Matsushita , Daiki Masukawa , Yusuke Mizuno , Hiraku Uchimura , Ryo Niikura , Tomoyuki Miyazaki , Fumio Nakamura , Suo Zou , Takahiro Shimizu , Motoaki Saito , Kouichi Tamura , Takahisa Goto , Yoshio Goshima

Loss of CRMP1 and CRMP2 results in migration defects of Purkinje cells in the X lobule of the mouse cerebellum.

Brain research

Avec: Satoshi Akinaga , Sayaka Harada , Miyuki Takahashi , Aosa Kaneko , Papachan Kolattukudy , Yoshio Goshima , Toshio Ohshima

Enhancement of haloperidol-induced catalepsy by GPR143, an L-DOPA receptor, in striatal cholinergic interneurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Masami Arai , Etsuko Suzuki , Satoshi Kitamura , Momoyo Otaki , Kaori Kanai , Miwako Yamasaki , Masahiko Watanabe , Yuki Kambe , Koshi Murata , Yuuki Takada , Tetsu Arisawa , Kenta Kobayashi , Rei Tajika , Tomoyuki Miyazaki , Masahiro Yamaguchi , Michael Lazarus , Yu Hayashi , Shigeyoshi Itohara , Alban de Kerchove d'Exaerde , Hiroyuki Nawa , Ryang Kim , Haruhiko Bito , Toshihiko Momiyama , Daiki Masukawa , Yoshio Goshima

Monoallelic

eLife

Avec: Ethiraj Ravindran , Nobuto Arashiki , Lena-Luise Becker , Kohtaro Takizawa , Jonathan Lévy , Thomas Rambaud , Konstantin L Makridis , Yoshio Goshima , Na Li , Maaike Vreeburg , Bénédicte Demeer , Achim Dickmanns , Alexander P A Stegmann , Hao Hu , Fumio Nakamura , Angela M Kaindl

The role of CRMP4 in LPS-induced neuroinflammation.

Brain research

Avec: Ryo Asahina , Miyuki Takahashi , Hiroshi Takano , Ryoji Yao , Manabu Abe , Yoshio Goshima , Toshio Ohshima

l-DOPA receptor GPR143 inhibits neurite outgrowth via L-type calcium channels in PC12 cells.

Journal of pharmacological sciences

Avec: Miyu Inoue , Daiki Masukawa , Yoshio Goshima

Genetic associations of single nucleotide polymorphisms in the l-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice.

Journal of pharmacological sciences

Avec: Daiki Masukawa , Daisuke Nishizawa , Kaori Kanai , Satoshi Kitamura , Yuka Kasahara , Tatsuo Hashimoto , Ryo Takahagi , Junko Hasegawa , Kyoko Nakayama , Naomi Sato , Fumihiko Tanioka , Haruhiko Sugimura , Kazutaka Ikeda , Yoshio Goshima

Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions.

Neuroscience research

Avec: Yuka Kasahara , Daiki Masukawa , Yoshie Nakamura , Koshi Murata , Tatsuo Hashimoto , Kohtaro Takizawa , Motokazu Koga , Fumio Nakamura , Yugo Fukazawa , Kengo Funakoshi , Yoshio Goshima

Addition of canagliflozin to insulin improves glycaemic control and reduces insulin dose in patients with type 2 diabetes mellitus: A randomized controlled trial.

Diabetes, obesity & metabolism

Avec: Keiichi Torimoto , Yosuke Okada , Yukiko Goshima , Akemi Tokutsu , Yasunori Sato , Yoshiya Tanaka

Regulation of axon pruning of mossy fiber projection in hippocampus by CRMP2 and CRMP4.

Developmental neurobiology

Avec: Yurika Nakanishi , Satoshi Akinaga , Koki Osawa , Natusmi Suzuki , Ayaka Sugeno , Papachan Kolattukudy , Yoshio Goshima , Toshio Ohshima

Cathodoluminescence Spectroscopic Stress Analysis for Silicon Oxide Film and Its Damage Evaluation.

Materials (Basel, Switzerland)

Avec: Shingo Kammachi , Yoshiharu Goshima , Nobutaka Goami , Naoaki Yamashita , Shigeru Kakinuma , Kentaro Nishikata , Nobuyuki Naka , Shozo Inoue , Takahiro Namazu

Changes in endothelial function during educational hospitalization and the contributor to improvement of endothelial function in type 2 diabetes mellitus.

Scientific reports

Avec: Yukiko Goshima , Yosuke Okada , Keiichi Torimoto , Yoshihisa Fujino , Yoshiya Tanaka

Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate.

Journal of pharmacological sciences

Avec: Hiraku Uchimura , Kaori Kanai , Masami Arai , Miyu Inoue , Akitoyo Hishimoto , Daiki Masukawa , Yoshio Goshima

Inhibition of CRMP2 Phosphorylation Suppresses Microglia Activation in the Retina and Optic Nerve and Promotes Optic Nerve Regeneration After Optic Nerve Injury.

Neuromolecular medicine

Avec: Yuebing Wang , Sayaka Harada , Yoshio Goshima , Toshio Ohshima

Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth.

Journal of neurochemistry

Avec: Takeshi Kawashima , Aoi Jitsuki-Takahashi , Kohtaro Takizawa , Susumu Jitsuki , Takuya Takahashi , Toshio Ohshima , Yoshio Goshima , Fumio Nakamura

Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's model mice.

Genes to cells : devoted to molecular & cellular mechanisms

Avec: Kentaro Togashi , Masaya Hasegawa , Jun Nagai , Aine Tonouchi , Daiki Masukawa , Kenneth Hensley , Yoshio Goshima , Toshio Ohshima

Overexpression of the gene product of ocular albinism 1 (GPR143/OA1) but not its mutant forms inhibits neurite outgrowth in PC12 cells.

Journal of pharmacological sciences

Avec: Daiki Masukawa , Kaisei Yamada , Yoshio Goshima

l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson's Disease.

Frontiers in pharmacology

Avec: Yoshio Goshima , Daiki Masukawa , Yuka Kasahara , Tatsuo Hashimoto , Aderemi Caleb Aladeokin

Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer's disease.

Neurobiology of disease

Avec: Aderemi Caleb Aladeokin , Tomoko Akiyama , Ayuko Kimura , Yayoi Kimura , Aoi Takahashi-Jitsuki , Haruko Nakamura , Hiroko Makihara , Daiki Masukawa , Jun Nakabayashi , Hisashi Hirano , Fumio Nakamura , Takashi Saito , Takaomi Saido , Yoshio Goshima

Inhibition of collapsin response mediator protein-2 phosphorylation ameliorates motor phenotype of ALS model mice expressing SOD1G93A.

Neuroscience research

Avec: Yurika Numata-Uematsu , Shuji Wakatsuki , Seiichi Nagano , Megumi Shibata , Kazuhisa Sakai , Noritaka Ichinohe , Katsuhiko Mikoshiba , Toshio Ohshima , Naoya Yamashita , Yoshiro Goshima , Toshiyuki Araki

Immunoreactivity of a G protein-coupled l-DOPA receptor GPR143, in Lewy bodies.

Neuroscience research

Avec: Yoshio Goshima , Shuya Watanabe , Erika Seki , Motokazu Koga , Daiki Masukawa , Fumio Nakamura , Takashi Komori , Nobutaka Arai

Réseau de co-auteurs

Daiki Masukawa 13 collaborations

Toshio Ohshima 9 collaborations

Fumio Nakamura 7 collaborations

Tatsuo Hashimoto 4 collaborations

Jun Nagai 3 collaborations

Miyuki Takahashi 3 collaborations

Motokazu Koga 3 collaborations

Kaori Kanai 3 collaborations

Kohtaro Takizawa 3 collaborations

Yuka Kasahara 3 collaborations

Shuji Wakatsuki 2 collaborations

Toshiyuki Araki 2 collaborations

Kentaro Togashi 2 collaborations

Masaya Hasegawa 2 collaborations

Kenneth Hensley 2 collaborations

Hiraku Uchimura 2 collaborations

Tomoyuki Miyazaki 2 collaborations

Satoshi Akinaga 2 collaborations

Sayaka Harada 2 collaborations

Papachan Kolattukudy 2 collaborations

Masami Arai 2 collaborations

Satoshi Kitamura 2 collaborations

Koshi Murata 2 collaborations

Miyu Inoue 2 collaborations

Keiichi Torimoto 2 collaborations

Yosuke Okada 2 collaborations

Yukiko Goshima 2 collaborations

Yoshiya Tanaka 2 collaborations

Aderemi Caleb Aladeokin 2 collaborations

Shunsuke Kondo 1 collaboration

Kazuya Takahashi 1 collaboration

Yuki Kinoshita 1 collaboration

Ken Kotaka 1 collaboration

Arina Yazawa 1 collaboration

Masaru Takabatake 1 collaboration

Yukio Sasaki 1 collaboration

Yuki Goshima 1 collaboration

Shinji Nakaoka 1 collaboration

Kazuteru Ohashi 1 collaboration

Hisashi Sakamaki 1 collaboration

Kazuko Shibuya 1 collaboration

Akira Shibuya 1 collaboration

Keiichi Yazawa 1 collaboration

Sho Sato 1 collaboration

Yukihiko Hiroshima 1 collaboration

Yasuhiro Yabushita 1 collaboration

Ryutaro Mori 1 collaboration

Ryusei Matsuyama 1 collaboration

Ikuma Kato 1 collaboration

Hideki Taniguchi 1 collaboration

Itaru Endo 1 collaboration

Masayuki Nakano 1 collaboration

Natsuki Matsushita 1 collaboration

Yusuke Mizuno 1 collaboration

Ryo Niikura 1 collaboration

Suo Zou 1 collaboration

Takahiro Shimizu 1 collaboration

Motoaki Saito 1 collaboration

Kouichi Tamura 1 collaboration

Takahisa Goto 1 collaboration

Aosa Kaneko 1 collaboration

Etsuko Suzuki 1 collaboration

Momoyo Otaki 1 collaboration

Miwako Yamasaki 1 collaboration

Masahiko Watanabe 1 collaboration

Yuki Kambe 1 collaboration

Yuuki Takada 1 collaboration

Tetsu Arisawa 1 collaboration

Kenta Kobayashi 1 collaboration

Rei Tajika 1 collaboration

Masahiro Yamaguchi 1 collaboration

Michael Lazarus 1 collaboration

Yu Hayashi 1 collaboration

Shigeyoshi Itohara 1 collaboration

Alban de Kerchove d'Exaerde 1 collaboration

Hiroyuki Nawa 1 collaboration

Ryang Kim 1 collaboration

Haruhiko Bito 1 collaboration

Toshihiko Momiyama 1 collaboration

Ethiraj Ravindran 1 collaboration

Nobuto Arashiki 1 collaboration

Lena-Luise Becker 1 collaboration

Jonathan Lévy 1 collaboration

Thomas Rambaud 1 collaboration

Konstantin L Makridis 1 collaboration

Na Li 1 collaboration

Maaike Vreeburg 1 collaboration

Bénédicte Demeer 1 collaboration

Achim Dickmanns 1 collaboration

Alexander P A Stegmann 1 collaboration

Hao Hu 1 collaboration

Angela M Kaindl 1 collaboration

Ryo Asahina 1 collaboration

Hiroshi Takano 1 collaboration

Ryoji Yao 1 collaboration

Manabu Abe 1 collaboration

Daisuke Nishizawa 1 collaboration

Ryo Takahagi 1 collaboration

Junko Hasegawa 1 collaboration

Kyoko Nakayama 1 collaboration

Naomi Sato 1 collaboration

Fumihiko Tanioka 1 collaboration

Haruhiko Sugimura 1 collaboration

Kazutaka Ikeda 1 collaboration

Yoshie Nakamura 1 collaboration

Yugo Fukazawa 1 collaboration

Kengo Funakoshi 1 collaboration

Akemi Tokutsu 1 collaboration

Yasunori Sato 1 collaboration

Yurika Nakanishi 1 collaboration

Koki Osawa 1 collaboration

Natusmi Suzuki 1 collaboration

Ayaka Sugeno 1 collaboration

Shingo Kammachi 1 collaboration

Yoshiharu Goshima 1 collaboration

Nobutaka Goami 1 collaboration

Naoaki Yamashita 1 collaboration

Shigeru Kakinuma 1 collaboration

Kentaro Nishikata 1 collaboration

Nobuyuki Naka 1 collaboration

Shozo Inoue 1 collaboration

Takahiro Namazu 1 collaboration

Yoshihisa Fujino 1 collaboration

Akitoyo Hishimoto 1 collaboration

Yuebing Wang 1 collaboration

Takeshi Kawashima 1 collaboration

Aoi Jitsuki-Takahashi 1 collaboration

Susumu Jitsuki 1 collaboration

Takuya Takahashi 1 collaboration

Aine Tonouchi 1 collaboration

Kaisei Yamada 1 collaboration

Tomoko Akiyama 1 collaboration

Ayuko Kimura 1 collaboration

Yayoi Kimura 1 collaboration

Aoi Takahashi-Jitsuki 1 collaboration

Haruko Nakamura 1 collaboration

Hiroko Makihara 1 collaboration

Jun Nakabayashi 1 collaboration

Hisashi Hirano 1 collaboration

Takashi Saito 1 collaboration

Takaomi Saido 1 collaboration

Yurika Numata-Uematsu 1 collaboration

Seiichi Nagano 1 collaboration

Megumi Shibata 1 collaboration

Kazuhisa Sakai 1 collaboration

Noritaka Ichinohe 1 collaboration

Katsuhiko Mikoshiba 1 collaboration

Naoya Yamashita 1 collaboration

Yoshiro Goshima 1 collaboration

Shuya Watanabe 1 collaboration

Erika Seki 1 collaboration

Takashi Komori 1 collaboration

Nobutaka Arai 1 collaboration