Wim Trypsteen

Affiliations

HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University and Ghent University Hospital, 9000 Ghent, Belgium.

Publications (27)

Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV.

International journal of molecular sciences

Avec: Tinus Schynkel , Matthew A Szaniawski , Adam M Spivak , Alberto Bosque , Vicente Planelles , Linos Vandekerckhove , Wim Trypsteen

Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size.

iScience

Avec: Marc J T Blaauw , Jéssica Cristina Dos Santos , Nadira Vadaq , Wim Trypsteen , Wouter van der Heijden , Albert Groenendijk , Zhenhua Zhang , Yang Li , Quirijn de Mast , Mihai G Netea , Leo A B Joosten , Linos Vandekerckhove , Andre van der Ven , Vasiliki Matzaraki

Digital PCR Partition Classification.

Clinical chemistry

Avec: Matthijs Vynck , Yao Chen , David Gleerup , Jo Vandesompele , Wim Trypsteen , Antoon Lievens , Olivier Thas , Ward De Spiegelaere

Organ-specific genome diversity of replication-competent SARS-CoV-2.

Nature communications

Avec: Jolien Van Cleemput , Willem van Snippenberg , Laurens Lambrechts , Amélie Dendooven , Valentino D'Onofrio , Liesbeth Couck , Wim Trypsteen , Jan Vanrusselt , Sebastiaan Theuns , Nick Vereecke , Thierry P P van den Bosch , Martin Lammens , Ann Driessen , Ruth Achten , Ken R Bracke , Wim Van den Broeck , Jan Von der Thüsen , Hans Nauwynck , Jo Van Dorpe , Sarah Gerlo , Piet Maes , Janneke Cox , Linos Vandekerckhove

The RNA Atlas expands the catalog of human non-coding RNAs.

Nature biotechnology

Avec: Lucia Lorenzi , Hua-Sheng Chiu , Francisco Avila Cobos , Stephen Gross , Pieter-Jan Volders , Robrecht Cannoodt , Justine Nuytens , Katrien Vanderheyden , Jasper Anckaert , Steve Lefever , Aidan P Tay , Eric J de Bony , Wim Trypsteen , Fien Gysens , Marieke Vromman , Tine Goovaerts , Thomas Birkballe Hansen , Scott Kuersten , Nele Nijs , Tom Taghon , Karim Vermaelen , Ken R Bracke , Yvan Saeys , Tim De Meyer , Nandan P Deshpande , Govardhan Anande , Ting-Wen Chen , Marc R Wilkins , Ashwin Unnikrishnan , Katleen De Preter , Jørgen Kjems , Jan Koster , Gary P Schroth , Jo Vandesompele , Pavel Sumazin , Pieter Mestdagh

People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells.

Scientific reports

Avec: Louise E van Eekeren , Vasiliki Matzaraki , Zhenhua Zhang , Lisa van de Wijer , Marc J T Blaauw , Marien I de Jonge , Linos Vandekerckhove , Wim Trypsteen , Leo A B Joosten , Mihai G Netea , Quirijn de Mast , Hans J P M Koenen , Yang Li , André J A M van der Ven

Interactome of the HIV-1 proteome and human host RNA.

EMBO reports

Avec: Tinus Schynkel , Willem van Snippenberg , Kimberly Verniers , Gwendolyn M Jang , Nevan J Krogan , Pieter Mestdagh , Linos Vandekerckhove , Wim Trypsteen

Long non-coding RNAs and latent HIV - A search for novel targets for latency reversal.

PloS one

Avec: Wim Trypsteen , Cory H White , Amey Mukim , Celsa A Spina , Ward De Spiegelaere , Steve Lefever , Vicente Planelles , Alberto Bosque , Christopher H Woelk , Linos Vandekerckhove , Nadejda Beliakova-Bethell

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.

JCI insight

Avec: Wouter A van der Heijden , Lisa Van de Wijer , Farid Keramati , Wim Trypsteen , Sofie Rutsaert , Rob Ter Horst , Martin Jaeger , Hans Jpm Koenen , Hendrik G Stunnenberg , Irma Joosten , Paul E Verweij , Jan van Lunzen , Charles A Dinarello , Leo Ab Joosten , Linos Vandekerckhove , Mihai G Netea , André Jam van der Ven , Quirijn de Mast

Triplex digital PCR assays for the quantification of intact proviral HIV-1 DNA.

Methods (San Diego, Calif.)

Avec: Willem van Snippenberg , David Gleerup , Sofie Rutsaert , Linos Vandekerckhove , Ward De Spiegelaere , Wim Trypsteen

Evaluating lncRNA Expression Patterns during HIV-1 Treatment Interruption.

International journal of molecular sciences

Avec: Tinus Schynkel , Willem van Snippenberg , Clarissa Van Hecke , Linos Vandekerckhove , Wim Trypsteen

Measuring DNA quality by digital PCR using probability calculations.

Analytica chimica acta

Avec: David Gleerup , Yao Chen , Willem Van Snippenberg , Cedric Valcke , Olivier Thas , Wim Trypsteen , Ward De Spiegelaere

Digital PCR threshold robustness analysis and optimization using dipcensR.

Briefings in bioinformatics

Avec: Matthijs Vynck , Wim Trypsteen , Olivier Thas , Jo Vandesompele , Ward De Spiegelaere

Emerging PCR-Based Techniques to Study HIV-1 Reservoir Persistence.

Viruses

Avec: Laurens Lambrechts , Basiel Cole , Sofie Rutsaert , Wim Trypsteen , Linos Vandekerckhove

A specific microRNA profile as predictive biomarker for systemic treatment in patients with metastatic colorectal cancer.

Cancer medicine

Avec: Dennis Poel , Elske C Gootjes , Lotte Bakkerus , Wim Trypsteen , Henk Dekker , Hans J van der Vliet , Nicole C T van Grieken , Cornelis Verhoef , Tineke E Buffart , Henk M W Verheul

Evolution of Experimental Design and Research Techniques in HIV-1 Reservoir Studies: A Systematic Review.

AIDS reviews

Avec: Marie-A De-Scheerder , Bram Depelseneer , Linos Vandekerckhove , Wim Trypsteen

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation.

Frontiers in immunology

Avec: Lisa Van de Wijer , Wouter A van der Heijden , Rob Ter Horst , Martin Jaeger , Wim Trypsteen , Sofie Rutsaert , Bram van Cranenbroek , Esther van Rijssen , Irma Joosten , Leo Joosten , Linos Vandekerckhove , Till Schoofs , Jan van Lunzen , Mihai G Netea , Hans J P M Koenen , André J A M van der Ven , Quirijn de Mast

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions.

Genes, chromosomes & cancer

Avec: Liselot M Mus , Stéphane Van Haver , Mina Popovic , Wim Trypsteen , Steve Lefever , Nadja Zeltner , Yudelca Ogando , Eva Z Jacobs , Geertrui Denecker , Ellen Sanders , Christophe Van Neste , Suzanne Vanhauwaert , Bieke Decaesteker , Dieter Deforce , Filip Van Nieuwerburgh , Pieter Mestdagh , Jo Vandesompele , Björn Menten , Katleen De Preter , Lorenz Studer , Björn Heindryckx , Kaat Durinck , Stephen Roberts , Frank Speleman

Benchmarking digital PCR partition classification methods with empirical and simulated duplex data.

Briefings in bioinformatics

Avec: Yao Chen , Ward De Spiegelaere , Wim Trypsteen , David Gleerup , Jo Vandesompele , Antoon Lievens , Matthijs Vynck , Olivier Thas

Evaluating predictive markers for viral rebound and safety assessment in blood and lumbar fluid during HIV-1 treatment interruption.

The Journal of antimicrobial chemotherapy

Avec: Marie-Angélique De Scheerder , Clarissa Van Hecke , Henrik Zetterberg , Dietmar Fuchs , Nele De Langhe , Sofie Rutsaert , Bram Vrancken , Wim Trypsteen , Ytse Noppe , Bea Van Der Gucht , Jolanda Pelgrom , Filip Van Wanzeele , Sarah Palmer , Philippe Lemey , Magnus Gisslén , Linos Vandekerckhove

Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals.

Clinical epigenetics

Avec: Sam Kint , Wim Trypsteen , Ward De Spiegelaere , Eva Malatinkova , Sabine Kinloch-de Loes , Tim De Meyer , Wim Van Criekinge , Linos Vandekerckhove

IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis.

BMC medicine

Avec: Zhenhua Zhang , Wim Trypsteen , Marc Blaauw , Xiaojing Chu , Sofie Rutsaert , Linos Vandekerckhove , Wouter van der Heijden , Jéssica Cristina Dos Santos , Cheng-Jian Xu , Morris A Swertz , Andre van der Ven , Yang Li

Digital Polymerase Chain Reaction for Assessment of Mutant Mitochondrial Carry-over after Nuclear Transfer for In Vitro Fertilization.

Clinical chemistry

Avec: Olivier Tytgat , Mao-Xing Tang , Willem van Snippenberg , Annekatrien Boel , Ramesh Reddy Guggilla , Yannick Gansemans , Michiel Van Herp , Sofie Symoens , Wim Trypsteen , Dieter Deforce , Björn Heindryckx , Paul Coucke , Ward De Spiegelaere , Filip Van Nieuwerburgh

On the whereabouts of SARS-CoV-2 in the human body: A systematic review.

PLoS pathogens

Avec: Wim Trypsteen , Jolien Van Cleemput , Willem van Snippenberg , Sarah Gerlo , Linos Vandekerckhove

A 3'-end capture sequencing method for high-throughput targeted gene expression profiling.

Biotechnology journal

Avec: Eric de Bony , Fien Gysens , Nurten Yigit , Jasper Anckaert , Celine Everaert , Eveline Vanden Eynde , Kimberly Verniers , Willem van Snippenberg , Wim Trypsteen , Pieter Mestdagh

Subpar reporting of pre-analytical variables in RNA-focused blood plasma studies.

Molecular oncology

Avec: Céleste Van Der Schueren , Philippe Decruyenaere , Francisco Avila Cobos , Johanna Bult , Jill Deleu , Laudonia Lidia Dipalo , Hetty Hilde Helsmoortel , Eva Hulstaert , Annelien Morlion , Elena Ramos Varas , Kathleen Schoofs , Wim Trypsteen , Eveline Vanden Eynde , Hanne Van Droogenbroeck , Kimberly Verniers , Jo Vandesompele , Anneleen Decock

In depth analysis of the HIV reservoir confirms effectiveness and safety of DTG/3TC in a phase 4 randomized controlled switch trial (RUMBA).

The Journal of infectious diseases

Avec: Marie-Angélique De Scheerder , Sophie Degroote , Mareva Delporte , Maja Kiselinova , Wim Trypsteen , Lara Vincke , Evelien De Smet , Bram Van Den Eeckhout , Loïc Schrooyen , Maxime Verschoore , Camilla Muccini , Sophie Vanherrewege , Els Caluwe , Stefanie De Buyser , Sarah Gerlo , Evy Blomme , Linos Vandekerckhove

Réseau de co-auteurs

Linos Vandekerckhove 17 collaborations

Ward De Spiegelaere 8 collaborations

Willem van Snippenberg 7 collaborations

Jo Vandesompele 6 collaborations

Sofie Rutsaert 6 collaborations

Quirijn de Mast 4 collaborations

Mihai G Netea 4 collaborations

David Gleerup 4 collaborations

Olivier Thas 4 collaborations

Pieter Mestdagh 4 collaborations

Tinus Schynkel 3 collaborations

Zhenhua Zhang 3 collaborations

Yang Li 3 collaborations

Matthijs Vynck 3 collaborations

Yao Chen 3 collaborations

Sarah Gerlo 3 collaborations

Steve Lefever 3 collaborations

Kimberly Verniers 3 collaborations

Alberto Bosque 2 collaborations

Vicente Planelles 2 collaborations

Marc J T Blaauw 2 collaborations

Jéssica Cristina Dos Santos 2 collaborations

Wouter van der Heijden 2 collaborations

Leo A B Joosten 2 collaborations

Andre van der Ven 2 collaborations

Vasiliki Matzaraki 2 collaborations

Antoon Lievens 2 collaborations

Jolien Van Cleemput 2 collaborations

Laurens Lambrechts 2 collaborations

Ken R Bracke 2 collaborations

Francisco Avila Cobos 2 collaborations

Jasper Anckaert 2 collaborations

Fien Gysens 2 collaborations

Tim De Meyer 2 collaborations

Katleen De Preter 2 collaborations

Hans J P M Koenen 2 collaborations

André J A M van der Ven 2 collaborations

Wouter A van der Heijden 2 collaborations

Lisa Van de Wijer 2 collaborations

Rob Ter Horst 2 collaborations

Martin Jaeger 2 collaborations

Irma Joosten 2 collaborations

Jan van Lunzen 2 collaborations

Clarissa Van Hecke 2 collaborations

Dieter Deforce 2 collaborations

Filip Van Nieuwerburgh 2 collaborations

Björn Heindryckx 2 collaborations

Marie-Angélique De Scheerder 2 collaborations

Eveline Vanden Eynde 2 collaborations

Matthew A Szaniawski 1 collaboration

Adam M Spivak 1 collaboration

Nadira Vadaq 1 collaboration

Albert Groenendijk 1 collaboration

Amélie Dendooven 1 collaboration

Valentino D'Onofrio 1 collaboration

Liesbeth Couck 1 collaboration

Jan Vanrusselt 1 collaboration

Sebastiaan Theuns 1 collaboration

Nick Vereecke 1 collaboration

Thierry P P van den Bosch 1 collaboration

Martin Lammens 1 collaboration

Ann Driessen 1 collaboration

Ruth Achten 1 collaboration

Wim Van den Broeck 1 collaboration

Jan Von der Thüsen 1 collaboration

Hans Nauwynck 1 collaboration

Jo Van Dorpe 1 collaboration

Piet Maes 1 collaboration

Janneke Cox 1 collaboration

Lucia Lorenzi 1 collaboration

Hua-Sheng Chiu 1 collaboration

Stephen Gross 1 collaboration

Pieter-Jan Volders 1 collaboration

Robrecht Cannoodt 1 collaboration

Justine Nuytens 1 collaboration

Katrien Vanderheyden 1 collaboration

Aidan P Tay 1 collaboration

Eric J de Bony 1 collaboration

Marieke Vromman 1 collaboration

Tine Goovaerts 1 collaboration

Thomas Birkballe Hansen 1 collaboration

Scott Kuersten 1 collaboration

Nele Nijs 1 collaboration

Tom Taghon 1 collaboration

Karim Vermaelen 1 collaboration

Yvan Saeys 1 collaboration

Nandan P Deshpande 1 collaboration

Govardhan Anande 1 collaboration

Ting-Wen Chen 1 collaboration

Marc R Wilkins 1 collaboration

Ashwin Unnikrishnan 1 collaboration

Jørgen Kjems 1 collaboration

Jan Koster 1 collaboration

Gary P Schroth 1 collaboration

Pavel Sumazin 1 collaboration

Louise E van Eekeren 1 collaboration

Lisa van de Wijer 1 collaboration

Marien I de Jonge 1 collaboration

Gwendolyn M Jang 1 collaboration

Nevan J Krogan 1 collaboration

Cory H White 1 collaboration

Amey Mukim 1 collaboration

Celsa A Spina 1 collaboration

Christopher H Woelk 1 collaboration

Nadejda Beliakova-Bethell 1 collaboration

Farid Keramati 1 collaboration

Hans Jpm Koenen 1 collaboration

Hendrik G Stunnenberg 1 collaboration

Paul E Verweij 1 collaboration

Charles A Dinarello 1 collaboration

Leo Ab Joosten 1 collaboration

André Jam van der Ven 1 collaboration

Willem Van Snippenberg 1 collaboration

Cedric Valcke 1 collaboration

Basiel Cole 1 collaboration

Dennis Poel 1 collaboration

Elske C Gootjes 1 collaboration

Lotte Bakkerus 1 collaboration

Henk Dekker 1 collaboration

Hans J van der Vliet 1 collaboration

Nicole C T van Grieken 1 collaboration

Cornelis Verhoef 1 collaboration

Tineke E Buffart 1 collaboration

Henk M W Verheul 1 collaboration

Marie-A De-Scheerder 1 collaboration

Bram Depelseneer 1 collaboration

Bram van Cranenbroek 1 collaboration

Esther van Rijssen 1 collaboration

Leo Joosten 1 collaboration

Till Schoofs 1 collaboration

Liselot M Mus 1 collaboration

Stéphane Van Haver 1 collaboration

Mina Popovic 1 collaboration

Nadja Zeltner 1 collaboration

Yudelca Ogando 1 collaboration

Eva Z Jacobs 1 collaboration

Geertrui Denecker 1 collaboration

Ellen Sanders 1 collaboration

Christophe Van Neste 1 collaboration

Suzanne Vanhauwaert 1 collaboration

Bieke Decaesteker 1 collaboration

Björn Menten 1 collaboration

Lorenz Studer 1 collaboration

Kaat Durinck 1 collaboration

Stephen Roberts 1 collaboration

Frank Speleman 1 collaboration

Henrik Zetterberg 1 collaboration

Dietmar Fuchs 1 collaboration

Nele De Langhe 1 collaboration

Bram Vrancken 1 collaboration

Ytse Noppe 1 collaboration

Bea Van Der Gucht 1 collaboration

Jolanda Pelgrom 1 collaboration

Filip Van Wanzeele 1 collaboration

Sarah Palmer 1 collaboration

Philippe Lemey 1 collaboration

Magnus Gisslén 1 collaboration

Sam Kint 1 collaboration

Eva Malatinkova 1 collaboration

Sabine Kinloch-de Loes 1 collaboration

Wim Van Criekinge 1 collaboration

Marc Blaauw 1 collaboration

Xiaojing Chu 1 collaboration

Cheng-Jian Xu 1 collaboration

Morris A Swertz 1 collaboration

Olivier Tytgat 1 collaboration

Mao-Xing Tang 1 collaboration

Annekatrien Boel 1 collaboration

Ramesh Reddy Guggilla 1 collaboration

Yannick Gansemans 1 collaboration

Michiel Van Herp 1 collaboration

Sofie Symoens 1 collaboration

Paul Coucke 1 collaboration

Eric de Bony 1 collaboration

Nurten Yigit 1 collaboration

Celine Everaert 1 collaboration

Céleste Van Der Schueren 1 collaboration

Philippe Decruyenaere 1 collaboration

Johanna Bult 1 collaboration

Jill Deleu 1 collaboration

Laudonia Lidia Dipalo 1 collaboration

Hetty Hilde Helsmoortel 1 collaboration

Eva Hulstaert 1 collaboration

Annelien Morlion 1 collaboration

Elena Ramos Varas 1 collaboration

Kathleen Schoofs 1 collaboration

Hanne Van Droogenbroeck 1 collaboration

Anneleen Decock 1 collaboration

Sophie Degroote 1 collaboration

Mareva Delporte 1 collaboration

Maja Kiselinova 1 collaboration

Lara Vincke 1 collaboration

Evelien De Smet 1 collaboration

Bram Van Den Eeckhout 1 collaboration

Loïc Schrooyen 1 collaboration

Maxime Verschoore 1 collaboration

Camilla Muccini 1 collaboration

Sophie Vanherrewege 1 collaboration

Els Caluwe 1 collaboration

Stefanie De Buyser 1 collaboration

Evy Blomme 1 collaboration