Wiebke Obermann

Affiliations

Institute of Pharmaceutical Chemistry, Philipps University Marburg, Marburg, Germany.

Publications (9)

Synthesis and antischistosomal activity of linker- and thiophene-modified biaryl alkyl carboxylic acid derivatives.

Archiv der Pharmazie

Avec: Alejandra M Peter Ventura , Simone Haeberlein , Leonie Konopka , Wiebke Obermann , Arnold Grünweller , Christoph G Grevelding , Martin Schlitzer

Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers.

JCI insight

Avec: Kai-Henrik Peiffer , Catrina Spengler , Michael Basic , Bingfu Jiang , Lisa Kuhnhenn , Wiebke Obermann , Tobias Zahn , Mirco Glitscher , Alessandro Loglio , Floriana Facchetti , Gert Carra , Alica Kubesch , Johannes Vermehren , Viola Knop , Christiana Graf , Julia Dietz , Fabian Finkelmeier , Eva Herrmann , Jonel Trebicka , Arnold Grünweller , Stefan Zeuzem , Christoph Sarrazin , Pietro Lampertico , Eberhard Hildt

Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity.

Viruses

Avec: Wiebke Obermann , Alexandra Friedrich , Ramakanth Madhugiri , Paul Klemm , Jan Philipp Mengel , Torsten Hain , Stephan Pleschka , Hans-Guido Wendel , Roland K Hartmann , Susanne Schiffmann , John Ziebuhr , Christin Müller , Arnold Grünweller

Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.

Antiviral research

Avec: Christin Müller , Wiebke Obermann , Falk W Schulte , Kerstin Lange-Grünweller , Lisa Oestereich , Fabian Elgner , Mirco Glitscher , Eberhard Hildt , Kamini Singh , Hans-Guido Wendel , Roland K Hartmann , John Ziebuhr , Arnold Grünweller

Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.

Scientific reports

Avec: Wiebke Obermann , Mohammad Farhan Darin Azri , Leonie Konopka , Nina Schmidt , Francesca Magari , Julian Sherman , Liliana M R Silva , Carlos Hermosilla , Andreas H Ludewig , Hicham Houhou , Simone Haeberlein , Mona Yiting Luo , Irina Häcker , Marc F Schetelig , Christoph G Grevelding , Frank C Schroeder , Gilbert Sei Kung Lau , Anja Taubert , Ana Rodriguez , Andreas Heine , Tiong Chia Yeo , Arnold Grünweller , Gaspar Taroncher-Oldenburg

The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo.

Antiviral research

Avec: Christin Müller , Wiebke Obermann , Nadja Karl , Hans-Guido Wendel , Gaspar Taroncher-Oldenburg , Stephan Pleschka , Roland K Hartmann , Arnold Grünweller , John Ziebuhr

Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates-A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics.

Microorganisms

Avec: Gaspar Taroncher-Oldenburg , Christin Müller , Wiebke Obermann , John Ziebuhr , Roland K Hartmann , Arnold Grünweller

First In Silico Screening of Insect Molecules for Identification of Novel Anti-Parasitic Compounds.

Pharmaceuticals (Basel, Switzerland)

Avec: Tom L Gallinger , Samuel Y Aboagye , Wiebke Obermann , Michael Weiss , Arnold Grünweller , Carlo Unverzagt , David L Williams , Martin Schlitzer , Simone Haeberlein

From dithiocarbamates to branched dithiocarbazates: Compounds with potent antischistosomal activity.

Archiv der Pharmazie

Avec: Tom L Gallinger , Wiebke Obermann , Kerstin Lange-Grünweller , Nina Schmidt , Simone Haeberlein , Arnold Grünweller , Christoph G Grevelding , Martin Schlitzer

Réseau de co-auteurs

Arnold Grünweller 9 collaborations

Simone Haeberlein 4 collaborations

Roland K Hartmann 4 collaborations

John Ziebuhr 4 collaborations

Christin Müller 4 collaborations

Christoph G Grevelding 3 collaborations

Martin Schlitzer 3 collaborations

Hans-Guido Wendel 3 collaborations

Gaspar Taroncher-Oldenburg 3 collaborations

Leonie Konopka 2 collaborations

Mirco Glitscher 2 collaborations

Eberhard Hildt 2 collaborations

Stephan Pleschka 2 collaborations

Kerstin Lange-Grünweller 2 collaborations

Nina Schmidt 2 collaborations

Tom L Gallinger 2 collaborations

Alejandra M Peter Ventura 1 collaboration

Kai-Henrik Peiffer 1 collaboration

Catrina Spengler 1 collaboration

Michael Basic 1 collaboration

Bingfu Jiang 1 collaboration

Lisa Kuhnhenn 1 collaboration

Tobias Zahn 1 collaboration

Alessandro Loglio 1 collaboration

Floriana Facchetti 1 collaboration

Gert Carra 1 collaboration

Alica Kubesch 1 collaboration

Johannes Vermehren 1 collaboration

Viola Knop 1 collaboration

Christiana Graf 1 collaboration

Julia Dietz 1 collaboration

Fabian Finkelmeier 1 collaboration

Eva Herrmann 1 collaboration

Jonel Trebicka 1 collaboration

Stefan Zeuzem 1 collaboration

Christoph Sarrazin 1 collaboration

Pietro Lampertico 1 collaboration

Alexandra Friedrich 1 collaboration

Ramakanth Madhugiri 1 collaboration

Paul Klemm 1 collaboration

Jan Philipp Mengel 1 collaboration

Torsten Hain 1 collaboration

Susanne Schiffmann 1 collaboration

Falk W Schulte 1 collaboration

Lisa Oestereich 1 collaboration

Fabian Elgner 1 collaboration

Kamini Singh 1 collaboration

Mohammad Farhan Darin Azri 1 collaboration

Francesca Magari 1 collaboration

Julian Sherman 1 collaboration

Liliana M R Silva 1 collaboration

Carlos Hermosilla 1 collaboration

Andreas H Ludewig 1 collaboration

Hicham Houhou 1 collaboration

Mona Yiting Luo 1 collaboration

Irina Häcker 1 collaboration

Marc F Schetelig 1 collaboration

Frank C Schroeder 1 collaboration

Gilbert Sei Kung Lau 1 collaboration

Anja Taubert 1 collaboration

Ana Rodriguez 1 collaboration

Andreas Heine 1 collaboration

Tiong Chia Yeo 1 collaboration

Nadja Karl 1 collaboration

Samuel Y Aboagye 1 collaboration

Michael Weiss 1 collaboration

Carlo Unverzagt 1 collaboration

David L Williams 1 collaboration