Valeria Rachela Villella

Affiliations

Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale (DICMAPI), Università di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
European Institute for Research in Cystic Fibrosis, San Raffaele Scientific Institute, Milan, Italy.

Publications (23)

Personalization of therapies in rare diseases: a translational approach for the treatment of cystic fibrosis.

Minerva pediatrica

Avec: Valeria R Villella , Antonella Tosco , Speranza Esposito , Eleonora Ferrari , Gianni Bona , Guido Kroemer , Valeria Raia , Luigi Maiuri

Collective rotational motion of freely expanding T84 epithelial cell colonies.

Journal of the Royal Society, Interface

Avec: Flora Ascione , Sergio Caserta , Speranza Esposito , Valeria Rachela Villella , Luigi Maiuri , Mehrana R Nejad , Amin Doostmohammadi , Julia M Yeomans , Stefano Guido

Theratyping of the Rare CFTR Genotype A559T in Rectal Organoids and Nasal Cells Reveals a Relevant Response to Elexacaftor (VX-445) and Tezacaftor (VX-661) Combination.

International journal of molecular sciences

Avec: Karina Kleinfelder , Valeria Rachela Villella , Anca Manuela Hristodor , Carlo Laudanna , Giuseppe Castaldo , Felice Amato , Paola Melotti , Claudio Sorio

Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis.

Cell death & disease

Avec: Valeria R Villella , Speranza Esposito , Eleonora Ferrari , Romina Monzani , Antonella Tosco , Federica Rossin , Alice Castaldo , Marco Silano , Gian Luigi Marseglia , Luigina Romani , Nikolai A Barlev , Mauro Piacentini , Valeria Raia , Guido Kroemer , Luigi Maiuri

Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.

The Journal of clinical investigation

Avec: Frank L van de Veerdonk , Giorgia Renga , Marilena Pariano , Marina M Bellet , Giuseppe Servillo , Francesca Fallarino , Antonella De Luca , Rossana G Iannitti , Danilo Piobbico , Marco Gargaro , Giorgia Manni , Fiorella D'Onofrio , Claudia Stincardini , Luigi Sforna , Monica Borghi , Marilena Castelli , Stefania Pieroni , Vasileios Oikonomou , Valeria R Villella , Matteo Puccetti , Stefano Giovagnoli , Roberta Galarini , Carolina Barola , Luigi Maiuri , Maria Agnese Della Fazia , Barbara Cellini , Vincenzo Nicola Talesa , Charles A Dinarello , Claudio Costantini , Luigina Romani

L1077P CFTR pathogenic variant function rescue by Elexacaftor-Tezacaftor-Ivacaftor in cystic fibrosis patient-derived air-liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients.

Respiratory research

Avec: Stefania Lo Cicero , Germana Castelli , Giovanna Blaconà , Sabina Maria Bruno , Giovanni Sette , Riccardo Pigliucci , Valeria Rachela Villella , Speranza Esposito , Immacolata Zollo , Francesca Spadaro , Ruggero De Maria , Mauro Biffoni , Giuseppe Cimino , Felice Amato , Marco Lucarelli , Adriana Eramo

Immuno-Sensing at Ultra-Low Concentration of TG2 Protein by Organic Electrochemical Transistors.

Biosensors

Avec: Valentina Preziosi , Mario Barra , Valeria Rachela Villella , Speranza Esposito , Pasquale D'Angelo , Simone Luigi Marasso , Matteo Cocuzza , Antonio Cassinese , Stefano Guido

Organic Electrochemical Transistor Immuno-Sensors for Spike Protein Early Detection.

Biosensors

Avec: Mario Barra , Giovanna Tomaiuolo , Valeria Rachela Villella , Speranza Esposito , Aris Liboà , Pasquale D'Angelo , Simone Luigi Marasso , Matteo Cocuzza , Valentina Bertana , Elena Camilli , Valentina Preziosi

Multiple antimicrobial and immune-modulating activities of cysteamine in infectious diseases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Tonino Alonzi , Alessandra Aiello , Michela Sali , Giovanni Delogu , Valeria Rachela Villella , Valeria Raia , Emanuele Nicastri , Mauro Piacentini , Delia Goletti

To Be or Not to Be a Pathogen:

Frontiers in immunology

Avec: Giorgia Renga , Marina M Bellet , Claudia Stincardini , Marilena Pariano , Vasilis Oikonomou , Valeria R Villella , Stefano Brancorsini , Carlo Clerici , Luigina Romani , Claudio Costantini

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis

Oncotarget

Avec: Luigi Maiuri , Valeria Raia , Mauro Piacentini , Antonella Tosco , Valeria Rachela Villella , Guido Kroemer

The gliadin-CFTR connection: new perspectives for the treatment of celiac disease.

Italian journal of pediatrics

Avec: Luigi Maiuri , Valeria R Villella , Valeria Raia , Guido Kroemer

Inhaled medications in cystic fibrosis beyond antibiotics.

Minerva pediatrica

Avec: Angela Sepe , Valeria R Villella , Chiara Cimbalo , Alice Castaldo , Francesco Nunziata , Adele Corcione , Gianni Bona , Luigi Maiuri , Valeria Raia

Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease.

Aging

Avec: Speranza Esposito , Valeria Rachela Villella , Eleonora Ferrari , Romina Monzani , Antonella Tosco , Federica Rossin , Manuela D'Eletto , Alice Castaldo , Alessandro Luciani , Marco Silano , Gianni Bona , Gian Luigi Marseglia , Luigina Romani , Mauro Piacentini , Valeria Raia , Guido Kroemer , Luigi Maiuri

Impaired cholesterol metabolism in the mouse model of cystic fibrosis. A preliminary study.

PloS one

Avec: Felice Amato , Alice Castaldo , Giuseppe Castaldo , Gustavo Cernera , Gaetano Corso , Eleonora Ferrari , Monica Gelzo , Romina Monzani , Valeria Rachela Villella , Valeria Raia

Probiotics Supplements Reduce ER Stress and Gut Inflammation Associated with Gliadin Intake in a Mouse Model of Gluten Sensitivity.

Nutrients

Avec: Eleonora Ferrari , Romina Monzani , Valentina Saverio , Mara Gagliardi , Elżbieta Pańczyszyn , Valeria Raia , Valeria Rachela Villella , Gianni Bona , Marco Pane , Angela Amoruso , Marco Corazzari

The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis.

Frontiers in immunology

Avec: Luca Occhigrossi , Federica Rossin , Valeria Rachela Villella , Speranza Esposito , Carlo Abbate , Manuela D'Eletto , Maria Grazia Farrace , Antonella Tosco , Roberta Nardacci , Gian Maria Fimia , Valeria Raia , Mauro Piacentini

Effect of CFTR Modulators on Oxidative Stress and Autophagy in Non-CFTR-Expressing Cells.

International journal of molecular sciences

Avec: Filippo Scialò , Gustavo Cernera , Lorenza Polise , Giuseppe Castaldo , Felice Amato , Valeria Rachela Villella

Mutation-specific therapies and drug repositioning in cystic fibrosis.

Minerva pediatrica

Avec: Valeria R Villella , Antonella Tosco , Speranza Esposito , Gianni Bona , Valeria Raia , Luigi Maiuri

Defective proteostasis in celiac disease as a new therapeutic target.

Cell death & disease

Avec: Luigi Maiuri , Valeria R Villella , Mauro Piacentini , Valeria Raia , Guido Kroemer

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.

The EMBO journal

Avec: Valeria R Villella , Andrea Venerando , Giorgio Cozza , Speranza Esposito , Eleonora Ferrari , Romina Monzani , Mara C Spinella , Vasilis Oikonomou , Giorgia Renga , Antonella Tosco , Federica Rossin , Stefano Guido , Marco Silano , Enrico Garaci , Yu-Kai Chao , Christian Grimm , Alessandro Luciani , Luigina Romani , Mauro Piacentini , Valeria Raia , Guido Kroemer , Luigi Maiuri

iScience

Avec: Karina Kleinfelder , Virginia Lotti , Adriana Eramo , Felice Amato , Stefania Lo Cicero , Germana Castelli , Francesca Spadaro , Alessia Farinazzo , Daniele Dell'Orco , Sara Preato , Jessica Conti , Luca Rodella , Francesco Tomba , Angelo Cerofolini , Elena Baldisseri , Marina Bertini , Sonia Volpi , Valeria Rachela Villella , Speranza Esposito , Immacolata Zollo , Giuseppe Castaldo , Carlo Laudanna , Eric J Sorsher , Jeong Hong , Disha Joshi , Garry Cutting , Marco Lucarelli , Paola Melotti , Claudio Sorio

The immune and microbial homeostasis determines the

Life science alliance

Avec: Giorgia Renga , Marilena Pariano , Fiorella D'Onofrio , Giuseppe Pieraccini , Claudia Di Serio , Valeria Rachela Villella , Carlo Abbate , Matteo Puccetti , Stefano Giovagnoli , Claudia Stincardini , Marina Maria Bellet , Maurizio Ricci , Claudio Costantini , Vasileios Oikonomou , Luigina Romani

Réseau de co-auteurs

Valeria Raia 13 collaborations

Speranza Esposito 11 collaborations

Luigi Maiuri 11 collaborations

Valeria R Villella 9 collaborations

Antonella Tosco 7 collaborations

Guido Kroemer 7 collaborations

Mauro Piacentini 7 collaborations

Eleonora Ferrari 6 collaborations

Luigina Romani 6 collaborations

Gianni Bona 5 collaborations

Felice Amato 5 collaborations

Romina Monzani 5 collaborations

Giuseppe Castaldo 4 collaborations

Federica Rossin 4 collaborations

Alice Castaldo 4 collaborations

Giorgia Renga 4 collaborations

Stefano Guido 3 collaborations

Marco Silano 3 collaborations

Marilena Pariano 3 collaborations

Claudia Stincardini 3 collaborations

Claudio Costantini 3 collaborations

Karina Kleinfelder 2 collaborations

Carlo Laudanna 2 collaborations

Paola Melotti 2 collaborations

Claudio Sorio 2 collaborations

Gian Luigi Marseglia 2 collaborations

Marina M Bellet 2 collaborations

Fiorella D'Onofrio 2 collaborations

Vasileios Oikonomou 2 collaborations

Matteo Puccetti 2 collaborations

Stefano Giovagnoli 2 collaborations

Stefania Lo Cicero 2 collaborations

Germana Castelli 2 collaborations

Immacolata Zollo 2 collaborations

Francesca Spadaro 2 collaborations

Marco Lucarelli 2 collaborations

Adriana Eramo 2 collaborations

Valentina Preziosi 2 collaborations

Mario Barra 2 collaborations

Pasquale D'Angelo 2 collaborations

Simone Luigi Marasso 2 collaborations

Matteo Cocuzza 2 collaborations

Vasilis Oikonomou 2 collaborations

Manuela D'Eletto 2 collaborations

Alessandro Luciani 2 collaborations

Gustavo Cernera 2 collaborations

Carlo Abbate 2 collaborations

Flora Ascione 1 collaboration

Sergio Caserta 1 collaboration

Mehrana R Nejad 1 collaboration

Amin Doostmohammadi 1 collaboration

Julia M Yeomans 1 collaboration

Anca Manuela Hristodor 1 collaboration

Nikolai A Barlev 1 collaboration

Frank L van de Veerdonk 1 collaboration

Giuseppe Servillo 1 collaboration

Francesca Fallarino 1 collaboration

Antonella De Luca 1 collaboration

Rossana G Iannitti 1 collaboration

Danilo Piobbico 1 collaboration

Marco Gargaro 1 collaboration

Giorgia Manni 1 collaboration

Luigi Sforna 1 collaboration

Monica Borghi 1 collaboration

Marilena Castelli 1 collaboration

Stefania Pieroni 1 collaboration

Roberta Galarini 1 collaboration

Carolina Barola 1 collaboration

Maria Agnese Della Fazia 1 collaboration

Barbara Cellini 1 collaboration

Vincenzo Nicola Talesa 1 collaboration

Charles A Dinarello 1 collaboration

Giovanna Blaconà 1 collaboration

Sabina Maria Bruno 1 collaboration

Giovanni Sette 1 collaboration

Riccardo Pigliucci 1 collaboration

Ruggero De Maria 1 collaboration

Mauro Biffoni 1 collaboration

Giuseppe Cimino 1 collaboration

Antonio Cassinese 1 collaboration

Giovanna Tomaiuolo 1 collaboration

Aris Liboà 1 collaboration

Valentina Bertana 1 collaboration

Elena Camilli 1 collaboration

Tonino Alonzi 1 collaboration

Alessandra Aiello 1 collaboration

Michela Sali 1 collaboration

Giovanni Delogu 1 collaboration

Emanuele Nicastri 1 collaboration

Delia Goletti 1 collaboration

Stefano Brancorsini 1 collaboration

Carlo Clerici 1 collaboration

Angela Sepe 1 collaboration

Chiara Cimbalo 1 collaboration

Francesco Nunziata 1 collaboration

Adele Corcione 1 collaboration

Gaetano Corso 1 collaboration

Monica Gelzo 1 collaboration

Valentina Saverio 1 collaboration

Mara Gagliardi 1 collaboration

Elżbieta Pańczyszyn 1 collaboration

Marco Pane 1 collaboration

Angela Amoruso 1 collaboration

Marco Corazzari 1 collaboration

Luca Occhigrossi 1 collaboration

Maria Grazia Farrace 1 collaboration

Roberta Nardacci 1 collaboration

Gian Maria Fimia 1 collaboration

Filippo Scialò 1 collaboration

Lorenza Polise 1 collaboration

Andrea Venerando 1 collaboration

Giorgio Cozza 1 collaboration

Mara C Spinella 1 collaboration

Enrico Garaci 1 collaboration

Yu-Kai Chao 1 collaboration

Christian Grimm 1 collaboration

Virginia Lotti 1 collaboration

Alessia Farinazzo 1 collaboration

Daniele Dell'Orco 1 collaboration

Sara Preato 1 collaboration

Jessica Conti 1 collaboration

Luca Rodella 1 collaboration

Francesco Tomba 1 collaboration

Angelo Cerofolini 1 collaboration

Elena Baldisseri 1 collaboration

Marina Bertini 1 collaboration

Sonia Volpi 1 collaboration

Eric J Sorsher 1 collaboration

Jeong Hong 1 collaboration

Disha Joshi 1 collaboration

Garry Cutting 1 collaboration

Giuseppe Pieraccini 1 collaboration

Claudia Di Serio 1 collaboration

Marina Maria Bellet 1 collaboration

Maurizio Ricci 1 collaboration