Ugonma Chukwueke

Affiliations

Division of Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Publications (16)

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases.

Nature communications

Avec: Sanjay M Prakadan , Christopher A Alvarez-Breckenridge , Samuel C Markson , Albert E Kim , Robert H Klein , Naema Nayyar , Andrew W Navia , Benjamin M Kuter , Kellie E Kolb , Ivanna Bihun , Joana L Mora , Mia Solana Bertalan , Brian Shaw , Michael White , Alexander Kaplan , Jackson H Stocking , Marc H Wadsworth , Eudocia Q Lee , Ugonma Chukwueke , Nancy Wang , Megha Subramanian , Denisse Rotem , Daniel P Cahill , Viktor A Adalsteinsson , Jeffrey W Miller , Ryan J Sullivan , Scott L Carter , Priscilla K Brastianos , Alex K Shalek

Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma.

Cureus

Avec: Daniel N Cagney , Michael B Miller , Adrian Dubuc , Ivana Delalle , Azra H Ligon , Ugonma Chukwueke , Ossama Al-Mefty , Ayal Aizer , Keith Ligon , Patrick Wen

EGFR mutant locally advanced non-small cell lung cancer is at increased risk of brain metastasis.

Clinical and translational radiation oncology

Avec: Devarati Mitra , Yu-Hui Chen , Richard Li , Gretchen Hermann , Katelyn Atkins , David Kozono , Elizabeth H Baldini , Ayal Aizer , Ugonma Chukwueke , Raymond H Mak

Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results.

Neuro-oncology

Avec: Wenya Linda Bi , Lakshmi Nayak , David M Meredith , Joseph Driver , Ziming Du , Samantha Hoffman , Yvonne Li , Eudocia Quant Lee , Rameen Beroukhim , Mikael Rinne , Ricardo McFaline-Figueroa , Ugonma Chukwueke , Christine McCluskey , Sarah Gaffey , Andrew D Cherniack , Jennifer Stefanik , Lisa Doherty , Christina Taubert , Meghan Cifrino , Deborah LaFrankie , Thomas Graillon , Patrick Y Wen , Keith L Ligon , Ossama Al-Mefty , Raymond Y Huang , Alona Muzikansky , E Antonio Chiocca , Sandro Santagata , Ian F Dunn , David A Reardon

Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: K Ina Ly , Leland G Richardson , Mofei Liu , Alona Muzikansky , Jonathan Cardona , Kevin Lou , Andrew L Beers , Ken Chang , James M Brown , Xiaoyue Ma , David A Reardon , Isabel C Arrillaga-Romany , Deborah A Forst , Justin T Jordan , Eudocia Q Lee , Jorg Dietrich , Lakshmi Nayak , Patrick Y Wen , Ugonma Chukwueke , Anita Giobbie-Hurder , Bryan D Choi , Tracy T Batchelor , Jayashree Kalpathy-Cramer , William T Curry , Elizabeth R Gerstner

Clinical and genomic predictors of adverse events in newly diagnosed glioblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Mary Jane Lim-Fat , J Bryan Iorgulescu , Rifaquat Rahman , Varun Bhave , Alona Muzikansky , Eleanor Woodward , Sydney Whorral , Marie Allen , Mehdi Touat , Xiaomei Li , Gongwen Xu , Jay Patel , Elizabeth R Gerstner , Jayashree Kalpathy-Cramer , Gilbert Youssef , Ugonma Chukwueke , J Ricardo McFaline-Figueroa , Lakshmi Nayak , Eudocia Q Lee , David A Reardon , Rameen Beroukhim , Raymond Y Huang , Wenya Linda Bi , Keith L Ligon , Patrick Y Wen

Publisher Correction: Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis.

Nature medicine

Avec: Priscilla K Brastianos , Eudocia Quant Lee , Justine V Cohen , Sara M Tolaney , Nancy U Lin , Nancy Wang , Ugonma Chukwueke , Michael D White , Naema Nayyar , Albert Kim , Christopher Alvarez-Breckenridge , Ian Krop , Maura Keeley Mahar , Mia S Bertalan , Brian Shaw , Joana L Mora , Nathaniel Goss , Megha Subramanian , Lakshmi Nayak , Jorg Dietrich , Deborah A Forst , Brian V Nahed , Tracy T Batchelor , Helen A Shih , Elizabeth R Gerstner , Beverly Moy , Donald Lawrence , Anita Giobbie-Hurder , Scott L Carter , Kevin Oh , Daniel P Cahill , Ryan J Sullivan

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma.

Nature genetics

Avec: David J H Shih , Naema Nayyar , Ivanna Bihun , Ibiayi Dagogo-Jack , Corey M Gill , Elisa Aquilanti , Mia Bertalan , Alexander Kaplan , Megan R D'Andrea , Ugonma Chukwueke , Franziska Maria Ippen , Christopher Alvarez-Breckenridge , Nicholas D Camarda , Matthew Lastrapes , Devin McCabe , Ben Kuter , Benjamin Kaufman , Matthew R Strickland , Juan Carlos Martinez-Gutierrez , Deepika Nagabhushan , Magali De Sauvage , Michael D White , Brandyn A Castro , Kaitlin Hoang , Andrew Kaneb , Emily D Batchelor , Sun Ha Paek , Sun Hye Park , Maria Martinez-Lage , Anna S Berghoff , Parker Merrill , Elizabeth R Gerstner , Tracy T Batchelor , Matthew P Frosch , Ryan P Frazier , Darrell R Borger , A John Iafrate , Bruce E Johnson , Sandro Santagata , Matthias Preusser , Daniel P Cahill , Scott L Carter , Priscilla K Brastianos

Clinical trial links oncolytic immunoactivation to survival in glioblastoma.

Nature

Avec: Alexander L Ling , Isaac H Solomon , Ana Montalvo Landivar , Hiroshi Nakashima , Jared K Woods , Andres Santos , Nafisa Masud , Geoffrey Fell , Xiaokui Mo , Ayse S Yilmaz , James Grant , Abigail Zhang , Joshua D Bernstock , Erickson Torio , Hirotaka Ito , Junfeng Liu , Naoyuki Shono , Michal O Nowicki , Daniel Triggs , Patrick Halloran , Raziye Piranlioglu , Himanshu Soni , Brittany Stopa , Wenya Linda Bi , Pierpaolo Peruzzi , Ethan Chen , Seth W Malinowski , Michael C Prabhu , Yu Zeng , Anne Carlisle , Scott J Rodig , Patrick Y Wen , Eudocia Quant Lee , Lakshmi Nayak , Ugonma Chukwueke , L Nicolas Gonzalez Castro , Sydney D Dumont , Tracy Batchelor , Kara Kittelberger , Ekaterina Tikhonova , Natalia Miheecheva , Dmitry Tabakov , Nara Shin , Alisa Gorbacheva , Artemy Shumskiy , Felix Frenkel , Estuardo Aguilar-Cordova , Laura K Aguilar , David Krisky , James Wechuck , Andrea Manzanera , Chris Matheny , Paul P Tak , Francesca Barone , Daniel Kovarsky , Itay Tirosh , Mario L Suvà , Kai W Wucherpfennig , Keith Ligon , David A Reardon , E Antonio Chiocca

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors.

Journal for immunotherapy of cancer

Avec: Li Zhu , Jessica L Narloch , Sayali Onkar , Marion Joy , Gloria Broadwater , Catherine Luedke , Allison Hall , Rim Kim , Katherine Pogue-Geile , Sarah Sammons , Naema Nayyar , Ugonma Chukwueke , Priscilla K Brastianos , Carey K Anders , Adam C Soloff , Dario A A Vignali , George C Tseng , Leisha A Emens , Peter C Lucas , Kimberly L Blackwell , Steffi Oesterreich , Adrian V Lee

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis.

Nature medicine

Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas.

Nature communications

Avec: Priscilla K Brastianos , Albert E Kim , Anita Giobbie-Hurder , Eudocia Quant Lee , Nancy Wang , April F Eichler , Ugonma Chukwueke , Deborah A Forst , Isabel C Arrillaga-Romany , Jorg Dietrich , Zachary Corbin , Jennifer Moliterno , Joachim Baehring , Michael White , Kevin W Lou , Juliana Larson , Magali A de Sauvage , Kathryn Evancic , Joana Mora , Naema Nayyar , Jay Loeffler , Kevin Oh , Helen A Shih , William T Curry , Daniel P Cahill , Fred G Barker , Elizabeth R Gerstner , Sandro Santagata

Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis.

Nature communications

Avec: Priscilla K Brastianos , Matthew R Strickland , Eudocia Quant Lee , Nancy Wang , Justine V Cohen , Ugonma Chukwueke , Deborah Anne Forst , April Eichler , Beth Overmoyer , Nancy U Lin , Wendy Y Chen , Aditya Bardia , Dejan Juric , Ibiayi Dagogo-Jack , Michael D White , Jorg Dietrich , Naema Nayyar , Albert E Kim , Christopher Alvarez-Breckenridge , Maura Mahar , Joana L Mora , Brian V Nahed , Pamela S Jones , Helen A Shih , Elizabeth R Gerstner , Anita Giobbie-Hurder , Scott L Carter , Kevin Oh , Daniel P Cahill , Ryan J Sullivan

Primary Central Nervous System Lymphomas.

Hematology/oncology clinics of North America

Avec: Ugonma Chukwueke , Christian Grommes , Lakshmi Nayak

Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making.

Neuro-oncology

Avec: Mary Jane Lim-Fat , Gilbert C Youssef , Mehdi Touat , J Bryan Iorgulescu , Sydney Whorral , Marie Allen , Rifaquat Rahman , Ugonma Chukwueke , J Ricardo McFaline-Figueroa , Lakshmi Nayak , Eudocia Q Lee , Tracy T Batchelor , Omar Arnaout , Pier Paolo Peruzzi , E Antonio Chiocca , David A Reardon , David Meredith , Sandro Santagata , Rameen Beroukhim , Wenya Linda Bi , Keith L Ligon , Patrick Y Wen

Re-irradiation of recurrent IDH-wildtype glioblastoma in the bevacizumab and immunotherapy era: Target delineation, outcomes and patterns of recurrence.

Clinical and translational radiation oncology

Avec: Sebastian M Christ , Gilbert Youssef , Shyam K Tanguturi , Daniel Cagney , Diana Shi , J Ricardo McFaline-Figueroa , Ugonma Chukwueke , Eudocia Q Lee , Caroline Hertler , Nicolaus Andratschke , Michael Weller , David A Reardon , Daphne Haas-Kogan , Matthias Guckenberger , Patrick Y Wen , Rifaquat Rahman

Réseau de co-auteurs

Lakshmi Nayak 8 collaborations

Naema Nayyar 7 collaborations

Priscilla K Brastianos 7 collaborations

Elizabeth R Gerstner 7 collaborations

Daniel P Cahill 6 collaborations

Eudocia Quant Lee 6 collaborations

Patrick Y Wen 6 collaborations

David A Reardon 6 collaborations

Eudocia Q Lee 5 collaborations

Nancy Wang 5 collaborations

Scott L Carter 5 collaborations

Jorg Dietrich 5 collaborations

Anita Giobbie-Hurder 5 collaborations

Tracy T Batchelor 5 collaborations

Joana L Mora 4 collaborations

Ryan J Sullivan 4 collaborations

Wenya Linda Bi 4 collaborations

Sandro Santagata 4 collaborations

Deborah A Forst 4 collaborations

Michael D White 4 collaborations

Christopher Alvarez-Breckenridge 4 collaborations

Helen A Shih 4 collaborations

Kevin Oh 4 collaborations

Albert E Kim 3 collaborations

Brian Shaw 3 collaborations

Megha Subramanian 3 collaborations

Rameen Beroukhim 3 collaborations

Keith L Ligon 3 collaborations

Alona Muzikansky 3 collaborations

E Antonio Chiocca 3 collaborations

Rifaquat Rahman 3 collaborations

J Ricardo McFaline-Figueroa 3 collaborations

Justine V Cohen 3 collaborations

Nancy U Lin 3 collaborations

Brian V Nahed 3 collaborations

Ivanna Bihun 2 collaborations

Michael White 2 collaborations

Alexander Kaplan 2 collaborations

Ossama Al-Mefty 2 collaborations

Ayal Aizer 2 collaborations

Keith Ligon 2 collaborations

Raymond Y Huang 2 collaborations

Isabel C Arrillaga-Romany 2 collaborations

Jayashree Kalpathy-Cramer 2 collaborations

William T Curry 2 collaborations

Mary Jane Lim-Fat 2 collaborations

J Bryan Iorgulescu 2 collaborations

Sydney Whorral 2 collaborations

Marie Allen 2 collaborations

Mehdi Touat 2 collaborations

Gilbert Youssef 2 collaborations

Sara M Tolaney 2 collaborations

Albert Kim 2 collaborations

Ian Krop 2 collaborations

Maura Keeley Mahar 2 collaborations

Mia S Bertalan 2 collaborations

Nathaniel Goss 2 collaborations

Beverly Moy 2 collaborations

Donald Lawrence 2 collaborations

Ibiayi Dagogo-Jack 2 collaborations

Matthew R Strickland 2 collaborations

Sanjay M Prakadan 1 collaboration

Christopher A Alvarez-Breckenridge 1 collaboration

Samuel C Markson 1 collaboration

Robert H Klein 1 collaboration

Andrew W Navia 1 collaboration

Benjamin M Kuter 1 collaboration

Kellie E Kolb 1 collaboration

Mia Solana Bertalan 1 collaboration

Jackson H Stocking 1 collaboration

Marc H Wadsworth 1 collaboration

Denisse Rotem 1 collaboration

Viktor A Adalsteinsson 1 collaboration

Jeffrey W Miller 1 collaboration

Alex K Shalek 1 collaboration

Daniel N Cagney 1 collaboration

Michael B Miller 1 collaboration

Adrian Dubuc 1 collaboration

Ivana Delalle 1 collaboration

Azra H Ligon 1 collaboration

Patrick Wen 1 collaboration

Devarati Mitra 1 collaboration

Yu-Hui Chen 1 collaboration

Richard Li 1 collaboration

Gretchen Hermann 1 collaboration

Katelyn Atkins 1 collaboration

David Kozono 1 collaboration

Elizabeth H Baldini 1 collaboration

Raymond H Mak 1 collaboration

David M Meredith 1 collaboration

Joseph Driver 1 collaboration

Ziming Du 1 collaboration

Samantha Hoffman 1 collaboration

Yvonne Li 1 collaboration

Mikael Rinne 1 collaboration

Ricardo McFaline-Figueroa 1 collaboration

Christine McCluskey 1 collaboration

Sarah Gaffey 1 collaboration

Andrew D Cherniack 1 collaboration

Jennifer Stefanik 1 collaboration

Lisa Doherty 1 collaboration

Christina Taubert 1 collaboration

Meghan Cifrino 1 collaboration

Deborah LaFrankie 1 collaboration

Thomas Graillon 1 collaboration

Ian F Dunn 1 collaboration

K Ina Ly 1 collaboration

Leland G Richardson 1 collaboration

Mofei Liu 1 collaboration

Jonathan Cardona 1 collaboration

Kevin Lou 1 collaboration

Andrew L Beers 1 collaboration

Ken Chang 1 collaboration

James M Brown 1 collaboration

Xiaoyue Ma 1 collaboration

Justin T Jordan 1 collaboration

Bryan D Choi 1 collaboration

Varun Bhave 1 collaboration

Eleanor Woodward 1 collaboration

Xiaomei Li 1 collaboration

Gongwen Xu 1 collaboration

Jay Patel 1 collaboration

David J H Shih 1 collaboration

Corey M Gill 1 collaboration

Elisa Aquilanti 1 collaboration

Mia Bertalan 1 collaboration

Megan R D'Andrea 1 collaboration

Franziska Maria Ippen 1 collaboration

Nicholas D Camarda 1 collaboration

Matthew Lastrapes 1 collaboration

Devin McCabe 1 collaboration

Ben Kuter 1 collaboration

Benjamin Kaufman 1 collaboration

Juan Carlos Martinez-Gutierrez 1 collaboration

Deepika Nagabhushan 1 collaboration

Magali De Sauvage 1 collaboration

Brandyn A Castro 1 collaboration

Kaitlin Hoang 1 collaboration

Andrew Kaneb 1 collaboration

Emily D Batchelor 1 collaboration

Sun Ha Paek 1 collaboration

Sun Hye Park 1 collaboration

Maria Martinez-Lage 1 collaboration

Anna S Berghoff 1 collaboration

Parker Merrill 1 collaboration

Matthew P Frosch 1 collaboration

Ryan P Frazier 1 collaboration

Darrell R Borger 1 collaboration

A John Iafrate 1 collaboration

Bruce E Johnson 1 collaboration

Matthias Preusser 1 collaboration

Alexander L Ling 1 collaboration

Isaac H Solomon 1 collaboration

Ana Montalvo Landivar 1 collaboration

Hiroshi Nakashima 1 collaboration

Jared K Woods 1 collaboration

Andres Santos 1 collaboration

Nafisa Masud 1 collaboration

Geoffrey Fell 1 collaboration

Xiaokui Mo 1 collaboration

Ayse S Yilmaz 1 collaboration

James Grant 1 collaboration

Abigail Zhang 1 collaboration

Joshua D Bernstock 1 collaboration

Erickson Torio 1 collaboration

Hirotaka Ito 1 collaboration

Junfeng Liu 1 collaboration

Naoyuki Shono 1 collaboration

Michal O Nowicki 1 collaboration

Daniel Triggs 1 collaboration

Patrick Halloran 1 collaboration

Raziye Piranlioglu 1 collaboration

Himanshu Soni 1 collaboration

Brittany Stopa 1 collaboration

Pierpaolo Peruzzi 1 collaboration

Ethan Chen 1 collaboration

Seth W Malinowski 1 collaboration

Michael C Prabhu 1 collaboration

Yu Zeng 1 collaboration

Anne Carlisle 1 collaboration

Scott J Rodig 1 collaboration

L Nicolas Gonzalez Castro 1 collaboration

Sydney D Dumont 1 collaboration

Tracy Batchelor 1 collaboration

Kara Kittelberger 1 collaboration

Ekaterina Tikhonova 1 collaboration

Natalia Miheecheva 1 collaboration

Dmitry Tabakov 1 collaboration

Nara Shin 1 collaboration

Alisa Gorbacheva 1 collaboration

Artemy Shumskiy 1 collaboration

Felix Frenkel 1 collaboration

Estuardo Aguilar-Cordova 1 collaboration

Laura K Aguilar 1 collaboration

David Krisky 1 collaboration

James Wechuck 1 collaboration

Andrea Manzanera 1 collaboration

Chris Matheny 1 collaboration

Paul P Tak 1 collaboration

Francesca Barone 1 collaboration

Daniel Kovarsky 1 collaboration

Itay Tirosh 1 collaboration

Mario L Suvà 1 collaboration

Kai W Wucherpfennig 1 collaboration

Li Zhu 1 collaboration

Jessica L Narloch 1 collaboration

Sayali Onkar 1 collaboration

Marion Joy 1 collaboration

Gloria Broadwater 1 collaboration

Catherine Luedke 1 collaboration

Allison Hall 1 collaboration

Rim Kim 1 collaboration

Katherine Pogue-Geile 1 collaboration

Sarah Sammons 1 collaboration

Carey K Anders 1 collaboration

Adam C Soloff 1 collaboration

Dario A A Vignali 1 collaboration

George C Tseng 1 collaboration

Leisha A Emens 1 collaboration

Peter C Lucas 1 collaboration

Kimberly L Blackwell 1 collaboration

Steffi Oesterreich 1 collaboration

Adrian V Lee 1 collaboration

April F Eichler 1 collaboration

Zachary Corbin 1 collaboration

Jennifer Moliterno 1 collaboration

Joachim Baehring 1 collaboration

Kevin W Lou 1 collaboration

Juliana Larson 1 collaboration

Magali A de Sauvage 1 collaboration

Kathryn Evancic 1 collaboration

Joana Mora 1 collaboration

Jay Loeffler 1 collaboration

Fred G Barker 1 collaboration

Deborah Anne Forst 1 collaboration

April Eichler 1 collaboration

Beth Overmoyer 1 collaboration

Wendy Y Chen 1 collaboration

Aditya Bardia 1 collaboration

Dejan Juric 1 collaboration

Maura Mahar 1 collaboration

Pamela S Jones 1 collaboration

Christian Grommes 1 collaboration

Gilbert C Youssef 1 collaboration

Omar Arnaout 1 collaboration

Pier Paolo Peruzzi 1 collaboration

David Meredith 1 collaboration

Sebastian M Christ 1 collaboration

Shyam K Tanguturi 1 collaboration

Daniel Cagney 1 collaboration

Diana Shi 1 collaboration

Caroline Hertler 1 collaboration

Nicolaus Andratschke 1 collaboration

Michael Weller 1 collaboration

Daphne Haas-Kogan 1 collaboration

Matthias Guckenberger 1 collaboration