Thomas W Chittenden

Affiliations

Computational Statistics and Bioinformatics Group, Advanced Artificial Intelligence Research Laboratory, WuXi NextCODE, Cambridge, MA, USA.
Complex Biological Systems Alliance, Medford, MA, USA.
Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Publications (8)

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.

Nature metabolism

Avec: Pei-Yu Chen , Lingfeng Qin , Guangxin Li , Zheng Wang , James E Dahlman , Jose Malagon-Lopez , Sharvari Gujja , Nicholas A Cilfone , Kevin J Kauffman , Lele Sun , Hongye Sun , Xinbo Zhang , Binod Aryal , Alberto Canfran-Duque , Rebecca Liu , Pascal Kusters , Alfica Sehgal , Yang Jiao , Daniel G Anderson , Jeffrey Gulcher , Carlos Fernandez-Hernando , Esther Lutgens , Martin A Schwartz , Jordan S Pober , Thomas W Chittenden , George Tellides , Michael Simons

Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification.

Journal of chemical information and modeling

Avec: Javier L Baylon , Nicholas A Cilfone , Jeffrey R Gulcher , Thomas W Chittenden

Smooth Muscle Cell Reprogramming in Aortic Aneurysms.

Cell stem cell

Avec: Pei-Yu Chen , Lingfeng Qin , Guangxin Li , Jose Malagon-Lopez , Zheng Wang , Sonia Bergaya , Sharvari Gujja , Alexander W Caulk , Sae-Il Murtada , Xinbo Zhang , Zhen W Zhuang , Deepak A Rao , Guilin Wang , Zuzana Tobiasova , Bo Jiang , Ruth R Montgomery , Lele Sun , Hongye Sun , Edward A Fisher , Jeffrey R Gulcher , Carlos Fernandez-Hernando , Jay D Humphrey , George Tellides , Thomas W Chittenden , Michael Simons

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

The Journal of clinical investigation

Avec: Guangxin Li , Mo Wang , Alexander W Caulk , Nicholas A Cilfone , Sharvari Gujja , Lingfeng Qin , Pei-Yu Chen , Zehua Chen , Sameh Yousef , Yang Jiao , Changshun He , Bo Jiang , Arina Korneva , Matthew R Bersi , Guilin Wang , Xinran Liu , Sameet Mehta , Arnar Geirsson , Jeffrey R Gulcher , Thomas W Chittenden , Michael Simons , Jay D Humphrey , George Tellides

Quantum processor-inspired machine learning in the biomedical sciences.

Patterns (New York, N.Y.)

Avec: Richard Y Li , Sharvari Gujja , Sweta R Bajaj , Omar E Gamel , Nicholas Cilfone , Jeffrey R Gulcher , Daniel A Lidar , Thomas W Chittenden

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort.

Science translational medicine

Avec: Raphael Carapito , Richard Li , Julie Helms , Christine Carapito , Sharvari Gujja , Véronique Rolli , Raony Guimaraes , Jose Malagon-Lopez , Perrine Spinnhirny , Alexandre Lederle , Razieh Mohseninia , Aurélie Hirschler , Leslie Muller , Paul Bastard , Adrian Gervais , Qian Zhang , François Danion , Yvon Ruch , Maleka Schenck , Olivier Collange , Thiên-Nga Chamaraux-Tran , Anne Molitor , Angélique Pichot , Alice Bernard , Ouria Tahar , Sabrina Bibi-Triki , Haiguo Wu , Nicodème Paul , Sylvain Mayeur , Annabel Larnicol , Géraldine Laumond , Julia Frappier , Sylvie Schmidt , Antoine Hanauer , Cécile Macquin , Tristan Stemmelen , Michael Simons , Xavier Mariette , Olivier Hermine , Samira Fafi-Kremer , Bernard Goichot , Bernard Drenou , Khaldoun Kuteifan , Julien Pottecher , Paul-Michel Mertes , Shweta Kailasan , M Javad Aman , Elisa Pin , Peter Nilsson , Anne Thomas , Alain Viari , Damien Sanlaville , Francis Schneider , Jean Sibilia , Pierre-Louis Tharaux , Jean-Laurent Casanova , Yves Hansmann , Daniel Lidar , Mirjana Radosavljevic , Jeffrey R Gulcher , Ferhat Meziani , Christiane Moog , Thomas W Chittenden , Seiamak Bahram

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium.

The Journal of experimental medicine

Avec: Nicolas Ricard , Rizaldy P Scott , Carmen J Booth , Heino Velazquez , Nicholas A Cilfone , Javier L Baylon , Jeffrey R Gulcher , Susan E Quaggin , Thomas W Chittenden , Michael Simons

ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia.

Cell reports

Avec: Jenny Lai , Didem Demirbas , Junho Kim , Ailsa M Jeffries , Allie Tolles , Junseok Park , Thomas W Chittenden , Patrick G Buckley , Timothy W Yu , Michael A Lodato , Eunjung Alice Lee

Réseau de co-auteurs

Jeffrey R Gulcher 6 collaborations

Sharvari Gujja 5 collaborations

Michael Simons 5 collaborations

Nicholas A Cilfone 4 collaborations

Pei-Yu Chen 3 collaborations

Lingfeng Qin 3 collaborations

Guangxin Li 3 collaborations

Jose Malagon-Lopez 3 collaborations

George Tellides 3 collaborations

Zheng Wang 2 collaborations

Lele Sun 2 collaborations

Hongye Sun 2 collaborations

Xinbo Zhang 2 collaborations

Yang Jiao 2 collaborations

Carlos Fernandez-Hernando 2 collaborations

Javier L Baylon 2 collaborations

Alexander W Caulk 2 collaborations

Guilin Wang 2 collaborations

Bo Jiang 2 collaborations

Jay D Humphrey 2 collaborations

James E Dahlman 1 collaboration

Kevin J Kauffman 1 collaboration

Binod Aryal 1 collaboration

Alberto Canfran-Duque 1 collaboration

Rebecca Liu 1 collaboration

Pascal Kusters 1 collaboration

Alfica Sehgal 1 collaboration

Daniel G Anderson 1 collaboration

Jeffrey Gulcher 1 collaboration

Esther Lutgens 1 collaboration

Martin A Schwartz 1 collaboration

Jordan S Pober 1 collaboration

Sonia Bergaya 1 collaboration

Sae-Il Murtada 1 collaboration

Zhen W Zhuang 1 collaboration

Deepak A Rao 1 collaboration

Zuzana Tobiasova 1 collaboration

Ruth R Montgomery 1 collaboration

Edward A Fisher 1 collaboration

Mo Wang 1 collaboration

Zehua Chen 1 collaboration

Sameh Yousef 1 collaboration

Changshun He 1 collaboration

Arina Korneva 1 collaboration

Matthew R Bersi 1 collaboration

Xinran Liu 1 collaboration

Sameet Mehta 1 collaboration

Arnar Geirsson 1 collaboration

Richard Y Li 1 collaboration

Sweta R Bajaj 1 collaboration

Omar E Gamel 1 collaboration

Nicholas Cilfone 1 collaboration

Daniel A Lidar 1 collaboration

Raphael Carapito 1 collaboration

Richard Li 1 collaboration

Julie Helms 1 collaboration

Christine Carapito 1 collaboration

Véronique Rolli 1 collaboration

Raony Guimaraes 1 collaboration

Perrine Spinnhirny 1 collaboration

Alexandre Lederle 1 collaboration

Razieh Mohseninia 1 collaboration

Aurélie Hirschler 1 collaboration

Leslie Muller 1 collaboration

Paul Bastard 1 collaboration

Adrian Gervais 1 collaboration

Qian Zhang 1 collaboration

François Danion 1 collaboration

Yvon Ruch 1 collaboration

Maleka Schenck 1 collaboration

Olivier Collange 1 collaboration

Thiên-Nga Chamaraux-Tran 1 collaboration

Anne Molitor 1 collaboration

Angélique Pichot 1 collaboration

Alice Bernard 1 collaboration

Ouria Tahar 1 collaboration

Sabrina Bibi-Triki 1 collaboration

Haiguo Wu 1 collaboration

Nicodème Paul 1 collaboration

Sylvain Mayeur 1 collaboration

Annabel Larnicol 1 collaboration

Géraldine Laumond 1 collaboration

Julia Frappier 1 collaboration

Sylvie Schmidt 1 collaboration

Antoine Hanauer 1 collaboration

Cécile Macquin 1 collaboration

Tristan Stemmelen 1 collaboration

Xavier Mariette 1 collaboration

Olivier Hermine 1 collaboration

Samira Fafi-Kremer 1 collaboration

Bernard Goichot 1 collaboration

Bernard Drenou 1 collaboration

Khaldoun Kuteifan 1 collaboration

Julien Pottecher 1 collaboration

Paul-Michel Mertes 1 collaboration

Shweta Kailasan 1 collaboration

M Javad Aman 1 collaboration

Elisa Pin 1 collaboration

Peter Nilsson 1 collaboration

Anne Thomas 1 collaboration

Alain Viari 1 collaboration

Damien Sanlaville 1 collaboration

Francis Schneider 1 collaboration

Jean Sibilia 1 collaboration

Pierre-Louis Tharaux 1 collaboration

Jean-Laurent Casanova 1 collaboration

Yves Hansmann 1 collaboration

Daniel Lidar 1 collaboration

Mirjana Radosavljevic 1 collaboration

Ferhat Meziani 1 collaboration

Christiane Moog 1 collaboration

Seiamak Bahram 1 collaboration

Nicolas Ricard 1 collaboration

Rizaldy P Scott 1 collaboration

Carmen J Booth 1 collaboration

Heino Velazquez 1 collaboration

Susan E Quaggin 1 collaboration

Jenny Lai 1 collaboration

Didem Demirbas 1 collaboration

Junho Kim 1 collaboration

Ailsa M Jeffries 1 collaboration

Allie Tolles 1 collaboration

Junseok Park 1 collaboration

Patrick G Buckley 1 collaboration

Timothy W Yu 1 collaboration

Michael A Lodato 1 collaboration

Eunjung Alice Lee 1 collaboration