Thomas D McCaffery

Affiliations

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.

ORCID: 0000-0002-7633-6008

Publications (3)

Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Kelly E Glajch , Tim E Moors , Yi Chen , Pascal A Bechade , Alice Y Nam , Molly M Rajsombath , Thomas D McCaffery , Ulf Dettmer , Andreas Weihofen , Warren D Hirst , Dennis J Selkoe , Silke Nuber

Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes.

NPJ Parkinson's disease

Avec: Silke Nuber , Xiaoqun Zhang , Thomas D McCaffery , Tim E Moors , Marie-Alexandre Adom , Wolf N Hahn , Dylan Martin , Maria Ericsson , Arathi Tripathi , Ulf Dettmer , Per Svenningsson , Dennis J Selkoe

Reducing the lipase LIPE in mutant α-synuclein mice improves Parkinson-like deficits and reveals sex differences in fatty acid metabolism.

Neurobiology of disease

Avec: M A Adom , W N Hahn , T D McCaffery , T E Moors , X Zhang , P Svenningsson , D J Selkoe , S Fanning , S Nuber

Réseau de co-auteurs

Tim E Moors 2 collaborations

Ulf Dettmer 2 collaborations

Dennis J Selkoe 2 collaborations

Silke Nuber 2 collaborations

Kelly E Glajch 1 collaboration

Yi Chen 1 collaboration

Pascal A Bechade 1 collaboration

Alice Y Nam 1 collaboration

Molly M Rajsombath 1 collaboration

Andreas Weihofen 1 collaboration

Warren D Hirst 1 collaboration

Xiaoqun Zhang 1 collaboration

Marie-Alexandre Adom 1 collaboration

Wolf N Hahn 1 collaboration

Dylan Martin 1 collaboration

Maria Ericsson 1 collaboration

Arathi Tripathi 1 collaboration

Per Svenningsson 1 collaboration

M A Adom 1 collaboration

W N Hahn 1 collaboration

T D McCaffery 1 collaboration

T E Moors 1 collaboration

X Zhang 1 collaboration

P Svenningsson 1 collaboration

D J Selkoe 1 collaboration

S Fanning 1 collaboration

S Nuber 1 collaboration