Stephen Hanessian

Affiliations

Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-Ville, Montréal, Québec, Canada, H3C3J7.

ORCID: https://orcid.org/0000-0003-3582-6972

Publications (27)

Computational and Further Experimental Explorations of the Competing Cascades Following Claisen Rearrangements of Aryl Propargyl Ethers: Substituent Effects on Reactivity and Regioselectivity.

The Journal of organic chemistry

Avec: Melissa Ramirez , Vito Vece , Stephen Hanessian , K N Houk

Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents.

Bioorganic & medicinal chemistry letters

Avec: Jean-Baptiste Garsi , Sofiane Hocine , Raphaël Hensienne , Matthieu Moitessier , Helen Denton , Louise L Major , Terry K Smith , Stephen Hanessian

Design and Synthesis of Backbone-Fused, Conformationally Constrained Morpholine-Proline Chimeras.

The Journal of organic chemistry

Avec: Sofiane Hocine , Gilles Berger , Stephen Hanessian

Total Synthesis and Stereochemical Confirmation of (-)-Olivil, (+)-Cycloolivil, (-)-Alashinols F and G, (+)-Cephafortin A, and Their Congeners: Filling in Biosynthetic Gaps.

Organic letters

Avec: Jithender Reddy Vakiti , Stephen Hanessian

Synthetic Sphingolipids with 1,2-Pyridazine Appendages Improve Antiproliferative Activity in Human Cancer Cell Lines.

ACS medicinal chemistry letters

Avec: Sylvestre P J T Bachollet , Vito Vece , Alison N McCracken , Brendan T Finicle , Elizabeth Selwan , Nadine Ben Romdhane , Amogha Dahal , Cuauhtemoc Ramirez , Aimee L Edinger , Stephen Hanessian

Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.

EMBO molecular medicine

Avec: Vaishali Jayashankar , Elizabeth Selwan , Sarah E Hancock , Amandine Verlande , Maggie O Goodson , Kazumi H Eckenstein , Giedre Milinkeviciute , Brianna M Hoover , Bin Chen , Angela G Fleischman , Karina S Cramer , Stephen Hanessian , Selma Masri , Nigel Turner , Aimee L Edinger

Pseudodiproline (Pro-Cyp) Oligomers Fold into Helical Polyproline Type secondary structures.

The Journal of organic chemistry

Avec: Jean-Baptiste Garsi , Pedro M Aguiar , Gilles Berger , Thierry Maris , Stephen Hanessian

Reductive Fragmentation of Tetrazoles: Mechanistic Insights and Applications toward the Stereocontrolled Synthesis of 2,6-Polysubstituted Morpholines.

Organic letters

Avec: Edouard Duchamp , Benoit Deschênes Simard , Stephen Hanessian

Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2A.

Bioorganic & medicinal chemistry letters

Avec: Jean-Baptiste Garsi , Vito Vece , Lorenzo Sernissi , Catherine Auger-Morin , Stephen Hanessian , Alison N McCracken , Elizabeth Selwan , Cuauhtemoc Ramirez , Amogha Dahal , Nadine Ben Romdhane , Brendan T Finicle , Aimee L Edinger

Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs.

Molecular & cellular proteomics : MCP

Avec: Peter Kubiniok , Brendan T Finicle , Fanny Piffaretti , Alison N McCracken , Michael Perryman , Stephen Hanessian , Aimee L Edinger , Pierre Thibault

Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics.

ACS medicinal chemistry letters

Avec: Jean-Baptiste Garsi , Balázs Komjáti , Gregorio Cullia , Imre Fejes , Melinda Sipos , Zoltán Sipos , Eszter Fördős , Piroska Markacz , Barbara Balázs , Nathalie Lancelot , Sylvie Berger , Eric Raimbaud , David Brown , Laurent-Michel Vuillard , Laure Haberkorn , Cyprian Cukier , Zoltán Szlávik , Stephen Hanessian

Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of 'first-in-kind' inhibitors of serine/threonine kinase25.

Bioorganic & medicinal chemistry letters

Avec: Scarlett Kiyeleko , Sofiane Hocine , Giséle Mautino , Mélaine Kuenemann , Agata Nawrotek , Linda Miallau , Laurent-Michel Vuillard , Olivier Mirguet , Andras Kotschy , Stephen Hanessian

Synthesis of Aza-Bridged Perhydroazulene Chimeras of Tropanes and Hederacine A.

The Journal of organic chemistry

Avec: Sofiane Hocine , Edouard Duchamp , Akash Mishra , Jean-Marie Fourquez , Stephen Hanessian

Design of Pseudodiproline Dimers as Mimetics of Pro-Pro Units: Stereocontrolled Synthesis, Configurational Relevance, and Structural Properties.

The Journal of organic chemistry

Avec: Jean-Baptiste Garsi , Pedro M Aguiar , Stephen Hanessian

Cyanide-Free Synthesis of Air Stable N-Substituted Li and K Cyanamide Salts from Tetrazoles. Applications toward the Synthesis of Primary and Secondary Cyanamides as Precursors to Amidines.

Organic letters

Avec: Edouard Duchamp , Stephen Hanessian

Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNA.

Journal of the American Chemical Society

Avec: Tamilselvan Rajasekaran , Graeme C Freestone , Rodrigo Galindo-Murillo , Barbara Lugato , Lorena Rico , Juan C Salinas , Hans Gaus , Michael T Migawa , Eric E Swayze , Thomas E Cheatham , Stephen Hanessian , Punit P Seth

Polygonapholine: A Total Synthesis Questions the Identity for the Purported Structure of the Natural Product.

The Journal of organic chemistry

Avec: Edouard Duchamp , Rory Devin , Pedro M Aguiar , Arthur Gaucherand , Stephen Hanessian

Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimers.

RSC advances

Avec: Edouard Duchamp , Guillermo Vasquez , Neda Firoozi , Graeme C Freestone , Michael Oestergaard , Punit P Seth , Stephen Hanessian

Synthesis of Azabicyclic Isosteres of Piperazine 2

The Journal of organic chemistry

Avec: Mick Vaillancourt , Akash Mishra , Edouard Duchamp , Stephen Hanessian

Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs.

Nucleosides, nucleotides & nucleic acids

Avec: Juan C Salinas , Punit P Seth , Stephen Hanessian

Synthesis of 1',2'-methano-2',3'-dideoxynucleosides as potential antivirals.

Bioorganic & medicinal chemistry letters

Avec: Lorena Rico , Stephen Hanessian

Ni-Catalyzed Reductive and Merged Photocatalytic Cross-Coupling Reactions toward sp

ACS omega

Avec: Adrien Dumas , Jean-Baptiste Garsi , Guillaume Poissonnet , Stephen Hanessian

Surprising Chemistry of 6-Azidotetrazolo[5,1-

The Journal of organic chemistry

Avec: Aaron Gabriel Nunez Avila , Benoît Deschênes-Simard , Joseph E Arnold , Mathieu Morency , Daniel Chartrand , Thierry Maris , Gilles Berger , Graeme M Day , Stephen Hanessian , James D Wuest

2-Oxa-5-azabicyclo[2.2.1]heptane as a Platform for Functional Diversity: Synthesis of Backbone-Constrained γ-Amino Acid Analogues.

The Journal of organic chemistry

Avec: Jean-Baptiste Garsi , Solène Guggari , Thomas Deis , Myles Ma , Sofiane Hocine , Stephen Hanessian

Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNA.

The Journal of organic chemistry

Avec: Tamilselvan Rajasekaran , Graeme C Freestone , Rodrigo Galindo-Murillo , Barbara Lugato , Hans Gaus , Michael T Migawa , Eric E Swayze , Thomas E Cheatham , Punit P Seth , Stephen Hanessian

Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics.

Nucleic acids research

Avec: Brendan T Finicle , Kazumi H Eckenstein , Alexey S Revenko , Brooke A Anderson , W Brad Wan , Alison N McCracken , Daniel Gil , David A Fruman , Stephen Hanessian , Punit P Seth , Aimee L Edinger

My 50-Plus Years of Academic Research Collaborations with Industry. A Retrospective.

The Journal of organic chemistry

Avec: Stephen Hanessian

Réseau de co-auteurs

Jean-Baptiste Garsi 7 collaborations

Edouard Duchamp 6 collaborations

Sofiane Hocine 5 collaborations

Aimee L Edinger 5 collaborations

Punit P Seth 5 collaborations

Alison N McCracken 4 collaborations

Brendan T Finicle 4 collaborations

Vito Vece 3 collaborations

Gilles Berger 3 collaborations

Elizabeth Selwan 3 collaborations

Pedro M Aguiar 3 collaborations

Graeme C Freestone 3 collaborations

Nadine Ben Romdhane 2 collaborations

Amogha Dahal 2 collaborations

Cuauhtemoc Ramirez 2 collaborations

Kazumi H Eckenstein 2 collaborations

Thierry Maris 2 collaborations

Laurent-Michel Vuillard 2 collaborations

Akash Mishra 2 collaborations

Tamilselvan Rajasekaran 2 collaborations

Rodrigo Galindo-Murillo 2 collaborations

Barbara Lugato 2 collaborations

Lorena Rico 2 collaborations

Juan C Salinas 2 collaborations

Hans Gaus 2 collaborations

Michael T Migawa 2 collaborations

Eric E Swayze 2 collaborations

Thomas E Cheatham 2 collaborations

Melissa Ramirez 1 collaboration

K N Houk 1 collaboration

Raphaël Hensienne 1 collaboration

Matthieu Moitessier 1 collaboration

Helen Denton 1 collaboration

Louise L Major 1 collaboration

Terry K Smith 1 collaboration

Jithender Reddy Vakiti 1 collaboration

Sylvestre P J T Bachollet 1 collaboration

Vaishali Jayashankar 1 collaboration

Sarah E Hancock 1 collaboration

Amandine Verlande 1 collaboration

Maggie O Goodson 1 collaboration

Giedre Milinkeviciute 1 collaboration

Brianna M Hoover 1 collaboration

Bin Chen 1 collaboration

Angela G Fleischman 1 collaboration

Karina S Cramer 1 collaboration

Selma Masri 1 collaboration

Nigel Turner 1 collaboration

Benoit Deschênes Simard 1 collaboration

Lorenzo Sernissi 1 collaboration

Catherine Auger-Morin 1 collaboration

Peter Kubiniok 1 collaboration

Fanny Piffaretti 1 collaboration

Michael Perryman 1 collaboration

Pierre Thibault 1 collaboration

Balázs Komjáti 1 collaboration

Gregorio Cullia 1 collaboration

Imre Fejes 1 collaboration

Melinda Sipos 1 collaboration

Zoltán Sipos 1 collaboration

Eszter Fördős 1 collaboration

Piroska Markacz 1 collaboration

Barbara Balázs 1 collaboration

Nathalie Lancelot 1 collaboration

Sylvie Berger 1 collaboration

Eric Raimbaud 1 collaboration

David Brown 1 collaboration

Laure Haberkorn 1 collaboration

Cyprian Cukier 1 collaboration

Zoltán Szlávik 1 collaboration

Scarlett Kiyeleko 1 collaboration

Giséle Mautino 1 collaboration

Mélaine Kuenemann 1 collaboration

Agata Nawrotek 1 collaboration

Linda Miallau 1 collaboration

Olivier Mirguet 1 collaboration

Andras Kotschy 1 collaboration

Jean-Marie Fourquez 1 collaboration

Rory Devin 1 collaboration

Arthur Gaucherand 1 collaboration

Guillermo Vasquez 1 collaboration

Neda Firoozi 1 collaboration

Michael Oestergaard 1 collaboration

Mick Vaillancourt 1 collaboration

Adrien Dumas 1 collaboration

Guillaume Poissonnet 1 collaboration

Aaron Gabriel Nunez Avila 1 collaboration

Benoît Deschênes-Simard 1 collaboration

Joseph E Arnold 1 collaboration

Mathieu Morency 1 collaboration

Daniel Chartrand 1 collaboration

Graeme M Day 1 collaboration

James D Wuest 1 collaboration

Solène Guggari 1 collaboration

Thomas Deis 1 collaboration

Myles Ma 1 collaboration

Alexey S Revenko 1 collaboration

Brooke A Anderson 1 collaboration

W Brad Wan 1 collaboration

Daniel Gil 1 collaboration

David A Fruman 1 collaboration