Simon Thebault

Affiliations

The Ottawa Hospital and Ottawa Hospital Research Institute, Ottawa, ON, Canada.

ORCID: 0000-0003-0395-3395

Publications (23)

Serum neurofilament light in MS: The first true blood-based biomarker?

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Simon Thebault , Gauruv Bose , Ronald Booth , Mark S Freedman

Serum Neurofilament Light Chain Measurement in MS: Hurdles to Clinical Translation.

Frontiers in neuroscience

Avec: Simon Thebault , Ronald A Booth , Carolina A Rush , Heather MacLean , Mark S Freedman

High or increasing serum NfL is predictive of impending multiple sclerosis relapses.

Multiple sclerosis and related disorders

Avec: Simon Thebault , Michael Reaume , Ruth Ann Marrie , James J Marriott , Roberto Furlan , Alice Laroni , Ronald A Booth , Antonio Uccelli , Mark S Freedman

Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis.

JAMA neurology

Avec: Anne H Cross , Jeffrey M Gelfand , Simon Thebault , Jeffrey L Bennett , H Christian von Büdingen , Briana Cameron , Robert Carruthers , Keith Edwards , Robert Fallis , Rachel Gerstein , Paul S Giacomini , Benjamin Greenberg , David A Hafler , Carolina Ionete , Ulrike W Kaunzner , Lay Kodama , Christopher Lock , Erin E Longbrake , Bruno Musch , Gabriel Pardo , Fredrik Piehl , Martin S Weber , Steven Yuen , Tjalf Ziemssen , Gauruv Bose , Mark S Freedman , Veronica G Anania , Akshaya Ramesh , Ryan C Winger , Xiaoming Jia , Ann Herman , Christopher Harp , Amit Bar-Or

Serum neurofilament light chain predicts long term clinical outcomes in multiple sclerosis.

Scientific reports

Avec: Simon Thebault , Mohammad Abdoli , Seyed-Mohammad Fereshtehnejad , Daniel Tessier , Vincent Tabard-Cossa , Mark S Freedman

MuSK not MNGIE: Atypical MuSK-antibody myasthenia presenting as a genetic disorder.

Neuromuscular disorders : NMD

Avec: Simon Thebault , Ebrima Gibbs , Pierre Bourque , Doug McKim , Kawan Rakhra , Ari Breiner , Hans Frykman , Jodi Warman-Chardon

Progressive Myelopathy With Acute Worsening After Steroids and Lumbar Puncture.

The Neurohospitalist

Avec: Simon Thebault , WooJin Kim , Jeremiah Hadwen , Gregory B Walker , Brian Drake , Tadeu A Fantaneanu

Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis.

Clinical proteomics

Avec: Lincoln I Wurtz , Evdokiya Knyazhanskaya , Dorsa Sohaei , Ioannis Prassas , Sean Pittock , Maria Alice V Willrich , Ruba Saadeh , Ruchi Gupta , Hunter J Atkinson , Diane Grill , Martin Stengelin , Simon Thebault , Mark S Freedman , Eleftherios P Diamandis , Isobel A Scarisbrick

High serum neurofilament light chain normalizes after hematopoietic stem cell transplantation for MS.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Simon Thebault , Daniel R Tessier , Hyunwoo Lee , Marjorie Bowman , Amit Bar-Or , Douglas L Arnold , Harold L Atkins , Vincent Tabard-Cossa , Mark S Freedman

Autologous hematopoietic stem cell transplantation for multiple sclerosis: A current perspective.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Gauruv Bose , Simon Thebault , Carolina A Rush , Harold L Atkins , Mark S Freedman

Isolated Internuclear Ophthalmoplegia as an Embolic Complication of Transcatheter Aortic Valve Implantation.

Cureus

Avec: Simon Thebault , Jodi Warman-Chardon , Kathleen O'Connell , William D Miller , Pierre R Bourque

Quantitation of neurofilament light chain protein in serum and cerebrospinal fluid from patients with multiple sclerosis using the MSD R-PLEX NfL assay.

Diagnosis (Berlin, Germany)

Avec: Antigona Ulndreaj , Dorsa Sohaei , Simon Thebault , Oscar D Pons-Belda , Amaia Fernandez-Uriarte , Christopher Campbell , David Cheo , Martin Stengelin , George Sigal , Mark S Freedman , Isobel A Scarisbrick , Ioannis Prassas , Eleftherios P Diamandis

Development and multi-center validation of a fully automated digital immunoassay for neurofilament light chain: toward a clinical blood test for neuronal injury.

Clinical chemistry and laboratory medicine

Avec: David Wilson , Dandan Chan , Lei Chang , Robert Mathis , Inge Verberk , Xavier Montalban , Manuel Comabella , Nicolas Fissolo , Bibi Bielekova , Ruturaj Masvekar , Tanuja Chitnis , Tjalf Ziemssen , Katja Akgün , Kaj Blennow , Henrik Zetterberg , Wolfgang Brück , Gavin Giovannoni , Sharmilee Gnanapavan , Stefan Bittner , Frauke Zipp , Giancarlo Comi , Roberto Furlan , Sylvain Lehmann , Simon Thebault , Mark Freedman , Amit Bar-Or , Marty Kramer , Markus Otto , Steffen Halbgebauer , Kevin Hrusovsky , Tatiana Plavina , Michael Khalil , Fredrik Piehl , Heinz Wiendl , Ludwig Kappos , Aleksandra Maceski , Eline Willemse , David Leppert , Charlotte Teunissen , Jens Kuhle

Neurofilaments as biomarkers in neurological disorders - towards clinical application.

Nature reviews. Neurology

Avec: Michael Khalil , Charlotte E Teunissen , Sylvain Lehmann , Markus Otto , Fredrik Piehl , Tjalf Ziemssen , Stefan Bittner , Maria Pia Sormani , Thomas Gattringer , Samir Abu-Rumeileh , Simon Thebault , Ahmed Abdelhak , Ari Green , Pascal Benkert , Ludwig Kappos , Manuel Comabella , Hayrettin Tumani , Mark S Freedman , Axel Petzold , Kaj Blennow , Henrik Zetterberg , David Leppert , Jens Kuhle

Neurotoxicity after hematopoietic stem cell transplant in multiple sclerosis.

Annals of clinical and translational neurology

Avec: Simon Thebault , Hyunwoo Lee , Gauruv Bose , Daniel Tessier , Mohammad Abdoli , Marjorie Bowman , Jason Berard , Lisa Walker , Carolina A Rush , Heather MacLean , Ronald A Booth , Sridar Narayanan , Douglas L Arnold , Vincent Tabard-Cossa , Harold L Atkins , Amit Bar-Or , Mark S Freedman

CLIPPERS Responsive to Cladribine as a Durable Steroid-Sparing Agent.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Simon Thebault , Hailey Bergman , Harold L Atkins , Mark S Freedman , John Brooks

Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis.

JAMA neurology

Avec: Stephanie Meier , Eline A J Willemse , Sabine Schaedelin , Johanna Oechtering , Johannes Lorscheider , Lester Melie-Garcia , Alessandro Cagol , Muhamed Barakovic , Riccardo Galbusera , Suvitha Subramaniam , Christian Barro , Ahmed Abdelhak , Simon Thebault , Lutz Achtnichts , Patrice Lalive , Stefanie Müller , Caroline Pot , Anke Salmen , Giulio Disanto , Chiara Zecca , Marcus D'Souza , Annette Orleth , Michael Khalil , Arabella Buchmann , Renaud Du Pasquier , Özgür Yaldizli , Tobias Derfuss , Klaus Berger , Marco Hermesdorf , Heinz Wiendl , Fredrik Piehl , Marco Battaglini , Urs Fischer , Ludwig Kappos , Claudio Gobbi , Cristina Granziera , Claire Bridel , David Leppert , Aleksandra Maleska Maceski , Pascal Benkert , Jens Kuhle

Blood Neurofilament Light Chain: The Neurologist's Troponin?

Biomedicines

Avec: Simon Thebault , Ronald A Booth , Mark S Freedman

Mesenchymal stem cell therapy and cognition in MS: Preliminary findings from a phase II clinical trial.

Multiple sclerosis and related disorders

Avec: Jason A Berard , Mark S Freedman , Ruth Ann Marrie , James J Marriott , Harold L Atkins , David Szwajcer , David W Courtman , Simon Thebault , Lisa A S Walker

Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy.

Gene therapy

Avec: Aoife Reilly , Marc-Olivier Deguise , Ariane Beauvais , Rebecca Yaworski , Simon Thebault , Daniel R Tessier , Vincent Tabard-Cossa , Niko Hensel , Bernard L Schneider , Rashmi Kothary

Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Simon Thebault , Stephanie Gandelman , Camryn Lane , Erin J Kim , Caitlin Pileggi , Leah Zuroff , Luana D Yamashita , Matthew K Schindler , Charles Chiu , Michael R Wilson , Joseph R Berger , Clyde Markowitz , Amit Bar-Or , Ryan Fuller , Rachel Brandstadter , Amy A Pruitt , Dina A Jacobs

Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis.

Clinical proteomics

Avec: Dorsa Sohaei , Simon Thebault , Lisa M Avery , Ihor Batruch , Brian Lam , Wei Xu , Rubah S Saadeh , Isobel A Scarisbrick , Eleftherios P Diamandis , Ioannis Prassas , Mark S Freedman

Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease.

Nature microbiology

Avec: Samantha S Soldan , Chenhe Su , Maria Chiara Monaco , Leena Yoon , Toshitha Kannan , Urvi Zankharia , Rishi J Patel , Jayaraju Dheekollu , Olga Vladimirova , Jack W Dowling , Simon Thebault , Natalie Brown , Annaliese Clauze , Frances Andrada , Andries Feder , Paul J Planet , Andrew Kossenkov , Daniel E Schäffer , Joan Ohayon , Noam Auslander , Steven Jacobson , Paul M Lieberman

Réseau de co-auteurs

Mark S Freedman 15 collaborations

Amit Bar-Or 5 collaborations

Harold L Atkins 5 collaborations

Gauruv Bose 4 collaborations

Ronald A Booth 4 collaborations

Fredrik Piehl 4 collaborations

Vincent Tabard-Cossa 4 collaborations

Carolina A Rush 3 collaborations

Tjalf Ziemssen 3 collaborations

Dorsa Sohaei 3 collaborations

Ioannis Prassas 3 collaborations

Eleftherios P Diamandis 3 collaborations

Isobel A Scarisbrick 3 collaborations

Michael Khalil 3 collaborations

Ludwig Kappos 3 collaborations

David Leppert 3 collaborations

Jens Kuhle 3 collaborations

Heather MacLean 2 collaborations

Ruth Ann Marrie 2 collaborations

James J Marriott 2 collaborations

Roberto Furlan 2 collaborations

Mohammad Abdoli 2 collaborations

Daniel Tessier 2 collaborations

Jodi Warman-Chardon 2 collaborations

Martin Stengelin 2 collaborations

Daniel R Tessier 2 collaborations

Hyunwoo Lee 2 collaborations

Marjorie Bowman 2 collaborations

Douglas L Arnold 2 collaborations

Manuel Comabella 2 collaborations

Kaj Blennow 2 collaborations

Henrik Zetterberg 2 collaborations

Stefan Bittner 2 collaborations

Sylvain Lehmann 2 collaborations

Markus Otto 2 collaborations

Heinz Wiendl 2 collaborations

Ahmed Abdelhak 2 collaborations

Pascal Benkert 2 collaborations

Ronald Booth 1 collaboration

Michael Reaume 1 collaboration

Alice Laroni 1 collaboration

Antonio Uccelli 1 collaboration

Anne H Cross 1 collaboration

Jeffrey M Gelfand 1 collaboration

Jeffrey L Bennett 1 collaboration

H Christian von Büdingen 1 collaboration

Briana Cameron 1 collaboration

Robert Carruthers 1 collaboration

Keith Edwards 1 collaboration

Robert Fallis 1 collaboration

Rachel Gerstein 1 collaboration

Paul S Giacomini 1 collaboration

Benjamin Greenberg 1 collaboration

David A Hafler 1 collaboration

Carolina Ionete 1 collaboration

Ulrike W Kaunzner 1 collaboration

Lay Kodama 1 collaboration

Christopher Lock 1 collaboration

Erin E Longbrake 1 collaboration

Bruno Musch 1 collaboration

Gabriel Pardo 1 collaboration

Martin S Weber 1 collaboration

Steven Yuen 1 collaboration

Veronica G Anania 1 collaboration

Akshaya Ramesh 1 collaboration

Ryan C Winger 1 collaboration

Xiaoming Jia 1 collaboration

Ann Herman 1 collaboration

Christopher Harp 1 collaboration

Seyed-Mohammad Fereshtehnejad 1 collaboration

Ebrima Gibbs 1 collaboration

Pierre Bourque 1 collaboration

Doug McKim 1 collaboration

Kawan Rakhra 1 collaboration

Ari Breiner 1 collaboration

Hans Frykman 1 collaboration

WooJin Kim 1 collaboration

Jeremiah Hadwen 1 collaboration

Gregory B Walker 1 collaboration

Brian Drake 1 collaboration

Tadeu A Fantaneanu 1 collaboration

Lincoln I Wurtz 1 collaboration

Evdokiya Knyazhanskaya 1 collaboration

Sean Pittock 1 collaboration

Maria Alice V Willrich 1 collaboration

Ruba Saadeh 1 collaboration

Ruchi Gupta 1 collaboration

Hunter J Atkinson 1 collaboration

Diane Grill 1 collaboration

Kathleen O'Connell 1 collaboration

William D Miller 1 collaboration

Pierre R Bourque 1 collaboration

Antigona Ulndreaj 1 collaboration

Oscar D Pons-Belda 1 collaboration

Amaia Fernandez-Uriarte 1 collaboration

Christopher Campbell 1 collaboration

David Cheo 1 collaboration

George Sigal 1 collaboration

David Wilson 1 collaboration

Dandan Chan 1 collaboration

Lei Chang 1 collaboration

Robert Mathis 1 collaboration

Inge Verberk 1 collaboration

Xavier Montalban 1 collaboration

Nicolas Fissolo 1 collaboration

Bibi Bielekova 1 collaboration

Ruturaj Masvekar 1 collaboration

Tanuja Chitnis 1 collaboration

Katja Akgün 1 collaboration

Wolfgang Brück 1 collaboration

Gavin Giovannoni 1 collaboration

Sharmilee Gnanapavan 1 collaboration

Frauke Zipp 1 collaboration

Giancarlo Comi 1 collaboration

Mark Freedman 1 collaboration

Marty Kramer 1 collaboration

Steffen Halbgebauer 1 collaboration

Kevin Hrusovsky 1 collaboration

Tatiana Plavina 1 collaboration

Aleksandra Maceski 1 collaboration

Eline Willemse 1 collaboration

Charlotte Teunissen 1 collaboration

Charlotte E Teunissen 1 collaboration

Maria Pia Sormani 1 collaboration

Thomas Gattringer 1 collaboration

Samir Abu-Rumeileh 1 collaboration

Ari Green 1 collaboration

Hayrettin Tumani 1 collaboration

Axel Petzold 1 collaboration

Jason Berard 1 collaboration

Lisa Walker 1 collaboration

Sridar Narayanan 1 collaboration

Hailey Bergman 1 collaboration

John Brooks 1 collaboration

Stephanie Meier 1 collaboration

Eline A J Willemse 1 collaboration

Sabine Schaedelin 1 collaboration

Johanna Oechtering 1 collaboration

Johannes Lorscheider 1 collaboration

Lester Melie-Garcia 1 collaboration

Alessandro Cagol 1 collaboration

Muhamed Barakovic 1 collaboration

Riccardo Galbusera 1 collaboration

Suvitha Subramaniam 1 collaboration

Christian Barro 1 collaboration

Lutz Achtnichts 1 collaboration

Patrice Lalive 1 collaboration

Stefanie Müller 1 collaboration

Caroline Pot 1 collaboration

Anke Salmen 1 collaboration

Giulio Disanto 1 collaboration

Chiara Zecca 1 collaboration

Marcus D'Souza 1 collaboration

Annette Orleth 1 collaboration

Arabella Buchmann 1 collaboration

Renaud Du Pasquier 1 collaboration

Özgür Yaldizli 1 collaboration

Tobias Derfuss 1 collaboration

Klaus Berger 1 collaboration

Marco Hermesdorf 1 collaboration

Marco Battaglini 1 collaboration

Urs Fischer 1 collaboration

Claudio Gobbi 1 collaboration

Cristina Granziera 1 collaboration

Claire Bridel 1 collaboration

Aleksandra Maleska Maceski 1 collaboration

Jason A Berard 1 collaboration

David Szwajcer 1 collaboration

David W Courtman 1 collaboration

Lisa A S Walker 1 collaboration

Aoife Reilly 1 collaboration

Marc-Olivier Deguise 1 collaboration

Ariane Beauvais 1 collaboration

Rebecca Yaworski 1 collaboration

Niko Hensel 1 collaboration

Bernard L Schneider 1 collaboration

Rashmi Kothary 1 collaboration

Stephanie Gandelman 1 collaboration

Camryn Lane 1 collaboration

Erin J Kim 1 collaboration

Caitlin Pileggi 1 collaboration

Leah Zuroff 1 collaboration

Luana D Yamashita 1 collaboration

Matthew K Schindler 1 collaboration

Charles Chiu 1 collaboration

Michael R Wilson 1 collaboration

Joseph R Berger 1 collaboration

Clyde Markowitz 1 collaboration

Ryan Fuller 1 collaboration

Rachel Brandstadter 1 collaboration

Amy A Pruitt 1 collaboration

Dina A Jacobs 1 collaboration

Lisa M Avery 1 collaboration

Ihor Batruch 1 collaboration

Brian Lam 1 collaboration

Wei Xu 1 collaboration

Rubah S Saadeh 1 collaboration

Samantha S Soldan 1 collaboration

Chenhe Su 1 collaboration

Maria Chiara Monaco 1 collaboration

Leena Yoon 1 collaboration

Toshitha Kannan 1 collaboration

Urvi Zankharia 1 collaboration

Rishi J Patel 1 collaboration

Jayaraju Dheekollu 1 collaboration

Olga Vladimirova 1 collaboration

Jack W Dowling 1 collaboration

Natalie Brown 1 collaboration

Annaliese Clauze 1 collaboration

Frances Andrada 1 collaboration

Andries Feder 1 collaboration

Paul J Planet 1 collaboration

Andrew Kossenkov 1 collaboration

Daniel E Schäffer 1 collaboration

Joan Ohayon 1 collaboration

Noam Auslander 1 collaboration

Steven Jacobson 1 collaboration

Paul M Lieberman 1 collaboration