Shuya Kyu

Publications (17)

Relaxed peripheral tolerance drives broad

medRxiv : the preprint server for health sciences

Avec: Matthew C Woodruff , Richard P Ramonell , Ankur Singh Saini , Natalie S Haddad , Fabliha A Anam , Mark E Rudolph , Regina Bugrovsky , Jennifer Hom , Kevin S Cashman , Doan C Nguyen , Shuya Kyu , Michael Piazza , Christopher M Tipton , Scott A Jenks , F Eun-Hyung Lee , Ignacio Sanz

Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells.

PloS one

Avec: Shuya Kyu , Richard P Ramonell , Merin Kuruvilla , Colleen S Kraft , Yun F Wang , Ann R Falsey , Edward E Walsh , John L Daiss , Simon Paulos , Gowrisankar Rajam , Hao Wu , Srinivasan Velusamy , F Eun-Hyung Lee

Differential transcriptome and development of human peripheral plasma cell subsets.

JCI insight

Avec: Swetha Garimalla , Doan C Nguyen , Jessica L Halliley , Christopher Tipton , Alexander F Rosenberg , Christopher F Fucile , Celia L Saney , Shuya Kyu , Denise Kaminski , Yu Qian , Richard H Scheuermann , Greg Gibson , Iñaki Sanz , F Eun-Hyung Lee

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.

Nature immunology

Avec: Matthew C Woodruff , Richard P Ramonell , Doan C Nguyen , Kevin S Cashman , Ankur Singh Saini , Natalie S Haddad , Ariel M Ley , Shuya Kyu , J Christina Howell , Tugba Ozturk , Saeyun Lee , Naveenchandra Suryadevara , James Brett Case , Regina Bugrovsky , Weirong Chen , Jacob Estrada , Andrea Morrison-Porter , Andrew Derrico , Fabliha A Anam , Monika Sharma , Henry M Wu , Sang N Le , Scott A Jenks , Christopher M Tipton , Bashar Staitieh , John L Daiss , Eliver Ghosn , Michael S Diamond , Robert H Carnahan , James E Crowe , William T Hu , F Eun-Hyung Lee , Ignacio Sanz

Heterofunctional Particles as Single Cell Sensors to Capture Secreted Immunoglobulins and Isolate Antigen-Specific Antibody Secreting Cells.

Advanced healthcare materials

Avec: Katily Ramirez , Shuya Kyu , Doan Nguyen , So-Yun Han , Ye Lim Lee , John Bradley , Troy Randall , Ignacio Sanz , Frances Eun-Hyung Lee , Todd Sulchek

Humoral immunity prevents clinical malaria during Plasmodium relapses without eliminating gametocytes.

PLoS pathogens

Avec: Chester J Joyner , Cristiana F A Brito , Celia L Saney , Regina Joice Cordy , Maren L Smith , Stacey A Lapp , Monica Cabrera-Mora , Shuya Kyu , Nicolas Lackman , Mustafa V Nural , Jeremy D DeBarry , Auteur inconnu , Jessica C Kissinger , Mark P Styczynski , F Eun-Hyung Lee , Tracey J Lamb , Mary R Galinski

Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.

Nature communications

Avec: Doan C Nguyen , Swetha Garimalla , Haopeng Xiao , Shuya Kyu , Igor Albizua , Jacques Galipeau , Kuang-Yueh Chiang , Edmund K Waller , Ronghu Wu , Greg Gibson , James Roberson , Frances E Lund , Troy D Randall , Iñaki Sanz , F Eun-Hyung Lee

One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses.

ImmunoHorizons

Avec: Natalie S Haddad , Doan C Nguyen , Merin E Kuruvilla , Andrea Morrison-Porter , Fabliha Anam , Kevin S Cashman , Richard P Ramonell , Shuya Kyu , Ankur Singh Saini , Monica Cabrera-Mora , Andrew Derrico , David Alter , John D Roback , Michael Horwath , James B O'Keefe , Henry M Wu , An-Kwok Ian Wong , Alexandra W Dretler , Ria Gripaldo , Andrea N Lane , Hao Wu , Helen Y Chu , Saeyun Lee , Mindy Hernandez , Vanessa Engineer , John Varghese , Rahul Patel , Anum Jalal , Victoria French , Ilya Guysenov , Christopher E Lane , Tesfaye Mengistsu , Katherine Elizabeth Normile , Onike Mnzava , Sang Le , Ignacio Sanz , John L Daiss , F Eun-Hyung Lee

Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.

Nature

Avec: Matthew C Woodruff , Richard P Ramonell , Natalie S Haddad , Fabliha A Anam , Mark E Rudolph , Tiffany A Walker , Alexander D Truong , Adviteeya N Dixit , Jenny E Han , Monica Cabrera-Mora , Martin C Runnstrom , Regina Bugrovsky , Jennifer Hom , Erin C Connolly , Igor Albizua , Vidhi Javia , Kevin S Cashman , Doan C Nguyen , Shuya Kyu , Ankur Singh Saini , Michael Piazza , Christopher M Tipton , Arezou Khosroshahi , Greg Gibson , Greg S Martin , Cheryl L Maier , Annette Esper , Scott A Jenks , F Eun-Hyung Lee , Ignacio Sanz

SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs.

Research square

Avec: Weirong Chen , So-Hee Hong , Scott A Jenks , Fabliha A Anam , Christopher M Tipton , Matthew C Woodruff , Jennifer R Hom , Kevin S Cashman , Caterina Elisa Faliti , Xiaoqian Wang , Shuya Kyu , Chungwen Wei , Christopher D Scharer , Tian Mi , Sakeenah Hicks , Louise Hartson , Doan C Nguyen , Arezou Khosroshahi , Saeyun Lee , Youliang Wang , Regina Bugrovsky , Yusho Ishii , F Eun-Hyung Lee , Ignacio Sanz

Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype.

Mucosal immunology

Avec: Richard P Ramonell , Margaret Brown , Matthew C Woodruff , Joshua M Levy , Sarah K Wise , John DelGaudio , Meixue Duan , Celia L Saney , Shuya Kyu , Kevin S Cashman , Jennifer R Hom , Christopher F Fucile , Alexander F Rosenberg , Christopher M Tipton , Ignacio Sanz , Gregory C Gibson , F Eun-Hyung Lee

Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.

The Journal of allergy and clinical immunology

Avec: Martin C Runnstrom , Pedro A Lamothe , Caterina E Faliti , Narayanaiah Cheedarla , Alberto Moreno , Mehul S Suthar , Rishika Nahata , Mayuran Ravindran , Natalie S Haddad , Andrea Morrison-Porter , Hannah Quehl , Richard P Ramonell , Matthew Woodruff , Fabliha Anam , Rebeca Zhang , Colin Swenson , Carmen Polito , Wendy Neveu , Rahulkumar Patel , Natalia Smirnova , Doan C Nyugen , Caroline Kim , Ian Hentenaar , Shuya Kyu , Sabeena Usman , Thuy Ngo , Zhenxing Guo , Hao Wu , John L Daiss , Jiwon Park , Kelly E Manning , Bursha Wali , Madison L Ellis , Sunita Sharma , Fernando Holguin , Suneethamma Cheedarla , Andrew S Neish , John D Roback , Ignacio Sanz , F Eun-Hyung Lee

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection.

bioRxiv : the preprint server for biology

Avec: Natalie S Haddad , Doan C Nguyen , Merin E Kuruvilla , Andrea Morrison-Porter , Fabliha Anam , Kevin S Cashman , Richard P Ramonell , Shuya Kyu , Ankur Singh Saini , Monica Cabrera-Mora , Andrew Derrico , David Alter , John D Roback , Michael Horwath , James B O'Keefe , Henry M Wu , An-Kwok Ian Wong , Alexandra W Dretler , Ria Gripaldo , Andrea N Lane , Hao Wu , Saeyun Lee , Mindy Hernandez , Vanessa Engineer , John Varghese , Sang Le , Iñaki Sanz , John L Daiss , F Eun-Hyung Lee

Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.

medRxiv : the preprint server for health sciences

Avec: Matthew Woodruff , Richard Ramonell , Kevin Cashman , Doan Nguyen , Ankur Saini , Natalie Haddad , Ariel Ley , Shuya Kyu , J Christina Howell , Tugba Ozturk , Saeyun Lee , Weirong Chen , Jacob Estrada , Andrea Morrison-Porter , Andrew Derrico , Fabliha Anam , Monika Sharma , Henry Wu , Sang Le , Scott Jenks , Christopher M Tipton , Wiliam Hu , F Eun-Hyung Lee , Ignacio Sanz

Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.

Nature communications

MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID.

medRxiv : the preprint server for health sciences

Avec: Natalie S Haddad , Andrea Morrison-Porter , Hannah Quehl , Violeta Capric , Pedro A Lamothe , Fabliha Anam , Martin C Runnstrom , Alex D Truong , Adviteeya N Dixit , Matthew C Woodruff , Anting Chen , Jiwon Park , Doan C Nguyen , Ian Hentenaar , Caroline Y Kim , Shuya Kyu , Brandon Stewart , Elizabeth Wagman , Hannah Geoffroy , Daniel Sanz , Kevin S Cashman , Richard P Ramonell , Monica Cabrera-Mora , David N Alter , John D Roback , Michael C Horwath , James B O'Keefe , Alexandra W Dretler , Ria Gripaldo , Samantha M Yeligar , Ted Natoli , Viktoria Betin , Rahulkumar Patel , Kennedy Vela , Mindy Rodriguez Hernandez , Sabeena Usman , John Varghese , Anum Jalal , Saeyun Lee , Sang N Le , R Toby Amoss , John L Daiss , Ignacio Sanz , F Eun-Hyung Lee

Poor immunogenicity upon SARS-CoV-2 mRNA vaccinations in autoimmune SLE patients is associated with pronounced EF-mediated responses and anti-BAFF/Belimumab treatment.

medRxiv : the preprint server for health sciences

Avec: Caterina E Faliti , Fabliha A Anam , Narayanaiah Cheedarla , Matthew C Woodruff , Sabeena Y Usman , Martin C Runnstrom , Trinh T P Van , Shuya Kyu , Hasan Ahmed , Andrea Morrison-Porter , Hannah Quehl , Natalie S Haddad , Weirong Chen , Suneethamma Cheedarla , Andrew S Neish , John D Roback , Rustom Antia , Arezou Khosroshahi , F Eun-Hyung Lee , Ignacio Sanz

Réseau de co-auteurs

F Eun-Hyung Lee 16 collaborations

Ignacio Sanz 12 collaborations

Doan C Nguyen 10 collaborations

Richard P Ramonell 9 collaborations

Kevin S Cashman 9 collaborations

Matthew C Woodruff 8 collaborations

Natalie S Haddad 8 collaborations

Christopher M Tipton 7 collaborations

Saeyun Lee 7 collaborations

Andrea Morrison-Porter 7 collaborations

Fabliha A Anam 6 collaborations

John L Daiss 6 collaborations

Ankur Singh Saini 5 collaborations

Regina Bugrovsky 5 collaborations

Scott A Jenks 5 collaborations

Weirong Chen 5 collaborations

Monica Cabrera-Mora 5 collaborations

Fabliha Anam 5 collaborations

John D Roback 5 collaborations

Hao Wu 4 collaborations

Andrew Derrico 4 collaborations

Martin C Runnstrom 4 collaborations

Arezou Khosroshahi 4 collaborations

Celia L Saney 3 collaborations

Greg Gibson 3 collaborations

Iñaki Sanz 3 collaborations

Henry M Wu 3 collaborations

James B O'Keefe 3 collaborations

Alexandra W Dretler 3 collaborations

Ria Gripaldo 3 collaborations

John Varghese 3 collaborations

Sang Le 3 collaborations

Jennifer R Hom 3 collaborations

Hannah Quehl 3 collaborations

Mark E Rudolph 2 collaborations

Jennifer Hom 2 collaborations

Michael Piazza 2 collaborations

Swetha Garimalla 2 collaborations

Alexander F Rosenberg 2 collaborations

Christopher F Fucile 2 collaborations

J Christina Howell 2 collaborations

Tugba Ozturk 2 collaborations

Jacob Estrada 2 collaborations

Monika Sharma 2 collaborations

Sang N Le 2 collaborations

Doan Nguyen 2 collaborations

Igor Albizua 2 collaborations

Merin E Kuruvilla 2 collaborations

David Alter 2 collaborations

Michael Horwath 2 collaborations

An-Kwok Ian Wong 2 collaborations

Andrea N Lane 2 collaborations

Mindy Hernandez 2 collaborations

Vanessa Engineer 2 collaborations

Anum Jalal 2 collaborations

Adviteeya N Dixit 2 collaborations

So-Hee Hong 2 collaborations

Caterina Elisa Faliti 2 collaborations

Xiaoqian Wang 2 collaborations

Chungwen Wei 2 collaborations

Christopher D Scharer 2 collaborations

Tian Mi 2 collaborations

Sakeenah Hicks 2 collaborations

Louise Hartson 2 collaborations

Youliang Wang 2 collaborations

Yusho Ishii 2 collaborations

Pedro A Lamothe 2 collaborations

Caterina E Faliti 2 collaborations

Narayanaiah Cheedarla 2 collaborations

Matthew Woodruff 2 collaborations

Rahulkumar Patel 2 collaborations

Ian Hentenaar 2 collaborations

Sabeena Usman 2 collaborations

Jiwon Park 2 collaborations

Suneethamma Cheedarla 2 collaborations

Andrew S Neish 2 collaborations

Merin Kuruvilla 1 collaboration

Colleen S Kraft 1 collaboration

Yun F Wang 1 collaboration

Ann R Falsey 1 collaboration

Edward E Walsh 1 collaboration

Simon Paulos 1 collaboration

Gowrisankar Rajam 1 collaboration

Srinivasan Velusamy 1 collaboration

Jessica L Halliley 1 collaboration

Christopher Tipton 1 collaboration

Denise Kaminski 1 collaboration

Yu Qian 1 collaboration

Richard H Scheuermann 1 collaboration

Ariel M Ley 1 collaboration

Naveenchandra Suryadevara 1 collaboration

James Brett Case 1 collaboration

Bashar Staitieh 1 collaboration

Eliver Ghosn 1 collaboration

Michael S Diamond 1 collaboration

Robert H Carnahan 1 collaboration

James E Crowe 1 collaboration

William T Hu 1 collaboration

Katily Ramirez 1 collaboration

So-Yun Han 1 collaboration

Ye Lim Lee 1 collaboration

John Bradley 1 collaboration

Troy Randall 1 collaboration

Frances Eun-Hyung Lee 1 collaboration

Todd Sulchek 1 collaboration

Chester J Joyner 1 collaboration

Cristiana F A Brito 1 collaboration

Regina Joice Cordy 1 collaboration

Maren L Smith 1 collaboration

Stacey A Lapp 1 collaboration

Nicolas Lackman 1 collaboration

Mustafa V Nural 1 collaboration

Jeremy D DeBarry 1 collaboration

None None 1 collaboration

Jessica C Kissinger 1 collaboration

Mark P Styczynski 1 collaboration

Tracey J Lamb 1 collaboration

Mary R Galinski 1 collaboration

Haopeng Xiao 1 collaboration

Jacques Galipeau 1 collaboration

Kuang-Yueh Chiang 1 collaboration

Edmund K Waller 1 collaboration

Ronghu Wu 1 collaboration

James Roberson 1 collaboration

Frances E Lund 1 collaboration

Troy D Randall 1 collaboration

Helen Y Chu 1 collaboration

Rahul Patel 1 collaboration

Victoria French 1 collaboration

Ilya Guysenov 1 collaboration

Christopher E Lane 1 collaboration

Tesfaye Mengistsu 1 collaboration

Katherine Elizabeth Normile 1 collaboration

Onike Mnzava 1 collaboration

Tiffany A Walker 1 collaboration

Alexander D Truong 1 collaboration

Jenny E Han 1 collaboration

Erin C Connolly 1 collaboration

Vidhi Javia 1 collaboration

Greg S Martin 1 collaboration

Cheryl L Maier 1 collaboration

Annette Esper 1 collaboration

Margaret Brown 1 collaboration

Joshua M Levy 1 collaboration

Sarah K Wise 1 collaboration

John DelGaudio 1 collaboration

Meixue Duan 1 collaboration

Gregory C Gibson 1 collaboration

Alberto Moreno 1 collaboration

Mehul S Suthar 1 collaboration

Rishika Nahata 1 collaboration

Mayuran Ravindran 1 collaboration

Rebeca Zhang 1 collaboration

Colin Swenson 1 collaboration

Carmen Polito 1 collaboration

Wendy Neveu 1 collaboration

Natalia Smirnova 1 collaboration

Doan C Nyugen 1 collaboration

Caroline Kim 1 collaboration

Thuy Ngo 1 collaboration

Zhenxing Guo 1 collaboration

Kelly E Manning 1 collaboration

Bursha Wali 1 collaboration

Madison L Ellis 1 collaboration

Sunita Sharma 1 collaboration

Fernando Holguin 1 collaboration

Richard Ramonell 1 collaboration

Kevin Cashman 1 collaboration

Ankur Saini 1 collaboration

Natalie Haddad 1 collaboration

Ariel Ley 1 collaboration

Henry Wu 1 collaboration

Scott Jenks 1 collaboration

Wiliam Hu 1 collaboration

Violeta Capric 1 collaboration

Alex D Truong 1 collaboration

Anting Chen 1 collaboration

Caroline Y Kim 1 collaboration

Brandon Stewart 1 collaboration

Elizabeth Wagman 1 collaboration

Hannah Geoffroy 1 collaboration

Daniel Sanz 1 collaboration

David N Alter 1 collaboration

Michael C Horwath 1 collaboration

Samantha M Yeligar 1 collaboration

Ted Natoli 1 collaboration

Viktoria Betin 1 collaboration

Kennedy Vela 1 collaboration

Mindy Rodriguez Hernandez 1 collaboration

R Toby Amoss 1 collaboration

Sabeena Y Usman 1 collaboration

Trinh T P Van 1 collaboration

Hasan Ahmed 1 collaboration

Rustom Antia 1 collaboration