Séverine Bégard

Affiliations

Univ. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France.

Publications (9)

Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Clément Danis , Elian Dupré , Orgeta Zejneli , Raphaëlle Caillierez , Alexis Arrial , Séverine Bégard , Justine Mortelecque , Sabiha Eddarkaoui , Anne Loyens , François-Xavier Cantrelle , Xavier Hanoulle , Jean-Christophe Rain , Morvane Colin , Luc Buée , Isabelle Landrieu

Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice.

Brain : a journal of neurology

Avec: Victoria Gomez-Murcia , Agathe Launay , Kévin Carvalho , Anaëlle Burgard , Céline Meriaux , Raphaëlle Caillierez , Sabiha Eddarkaoui , Devrim Kilinc , Dolores Siedlecki-Wullich , Mélanie Besegher , Séverine Bégard , Bryan Thiroux , Matthieu Jung , Ouada Nebie , Maxence Wisztorski , Nicole Déglon , Claire Montmasson , Alexis-Pierre Bemelmans , Malika Hamdane , Thibaud Lebouvier , Didier Vieau , Isabelle Fournier , Luc Buee , Sabine Lévi , Luisa V Lopes , Anne-Laurence Boutillier , Emilie Faivre , David Blum

Integration of Microfluidic Devices with Microelectrode Arrays to Functionally Assay Amyloid-β-Induced Synaptotoxicity.

ACS biomaterials science & engineering

Avec: Camille Lefebvre , Anaïs-Camille Vreulx , Corentin Dumortier , Séverine Bégard , Carla Gelle , Dolores Siedlecki-Wullich , Morvane Colin , Devrim Kilinc , Sophie Halliez

Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process.

Cell death & disease

Avec: Manon Domise , Florent Sauvé , Sébastien Didier , Raphaëlle Caillerez , Séverine Bégard , Sébastien Carrier , Morvane Colin , Claudia Marinangeli , Luc Buée , Valérie Vingtdeux

Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Elodie Leroux , Romain Perbet , Raphaëlle Caillierez , Kevin Richetin , Sarah Lieger , Jeanne Espourteille , Thomas Bouillet , Séverine Bégard , Clément Danis , Anne Loyens , Nicolas Toni , Nicole Déglon , Vincent Deramecourt , Susanna Schraen-Maschke , Luc Buée , Morvane Colin

Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.

Nature neuroscience

Avec: Kevin Richetin , Pascal Steullet , Mathieu Pachoud , Romain Perbet , Enea Parietti , Mathischan Maheswaran , Sabiha Eddarkaoui , Séverine Bégard , Catherine Pythoud , Maria Rey , Raphaëlle Caillierez , Kim Q Do , Sophie Halliez , Paola Bezzi , Luc Buée , Geneviève Leuba , Morvane Colin , Nicolas Toni , Nicole Déglon

Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer's disease.

Progress in neurobiology

Avec: Marine Denechaud , Sarah Geurs , Thomas Comptdaer , Séverine Bégard , Alejandro Garcia-Núñez , Louis-Adrien Pechereau , Thomas Bouillet , Yannick Vermeiren , Peter P De Deyn , Romain Perbet , Vincent Deramecourt , Claude-Alain Maurage , Michiel Vanderhaegen , Sebastiaan Vanuytven , Bruno Lefebvre , Elke Bogaert , Nicole Déglon , Thierry Voet , Morvane Colin , Luc Buée , Bart Dermaut , Marie-Christine Galas

Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System.

Cells

Avec: Romain Perbet , Valentin Zufferey , Elodie Leroux , Enea Parietti , Jeanne Espourteille , Lucas Culebras , Sylvain Perriot , Renaud Du Pasquier , Séverine Bégard , Vincent Deramecourt , Nicole Déglon , Nicolas Toni , Luc Buée , Morvane Colin , Kevin Richetin

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the Tau intrinsically disordered protein.

The Journal of biological chemistry

Avec: Justine Mortelecque , Orgeta Zejneli , Séverine Bégard , Margarida C Simões , Lea ElHajjar , Marine Nguyen , François-Xavier Cantrelle , Xavier Hanoulle , Jean-Christophe Rain , Morvane Colin , Cláudio M Gomes , Luc Buée , Isabelle Landrieu , Clément Danis , Elian Dupré

Réseau de co-auteurs

Morvane Colin 8 collaborations

Luc Buée 7 collaborations

Nicole Déglon 5 collaborations

Raphaëlle Caillierez 4 collaborations

Romain Perbet 4 collaborations

Clément Danis 3 collaborations

Sabiha Eddarkaoui 3 collaborations

Kevin Richetin 3 collaborations

Nicolas Toni 3 collaborations

Vincent Deramecourt 3 collaborations

Elian Dupré 2 collaborations

Orgeta Zejneli 2 collaborations

Justine Mortelecque 2 collaborations

Anne Loyens 2 collaborations

François-Xavier Cantrelle 2 collaborations

Xavier Hanoulle 2 collaborations

Jean-Christophe Rain 2 collaborations

Isabelle Landrieu 2 collaborations

Devrim Kilinc 2 collaborations

Dolores Siedlecki-Wullich 2 collaborations

Sophie Halliez 2 collaborations

Elodie Leroux 2 collaborations

Jeanne Espourteille 2 collaborations

Thomas Bouillet 2 collaborations

Enea Parietti 2 collaborations

Alexis Arrial 1 collaboration

Victoria Gomez-Murcia 1 collaboration

Agathe Launay 1 collaboration

Kévin Carvalho 1 collaboration

Anaëlle Burgard 1 collaboration

Céline Meriaux 1 collaboration

Mélanie Besegher 1 collaboration

Bryan Thiroux 1 collaboration

Matthieu Jung 1 collaboration

Ouada Nebie 1 collaboration

Maxence Wisztorski 1 collaboration

Claire Montmasson 1 collaboration

Alexis-Pierre Bemelmans 1 collaboration

Malika Hamdane 1 collaboration

Thibaud Lebouvier 1 collaboration

Didier Vieau 1 collaboration

Isabelle Fournier 1 collaboration

Luc Buee 1 collaboration

Sabine Lévi 1 collaboration

Luisa V Lopes 1 collaboration

Anne-Laurence Boutillier 1 collaboration

Emilie Faivre 1 collaboration

David Blum 1 collaboration

Camille Lefebvre 1 collaboration

Anaïs-Camille Vreulx 1 collaboration

Corentin Dumortier 1 collaboration

Carla Gelle 1 collaboration

Manon Domise 1 collaboration

Florent Sauvé 1 collaboration

Sébastien Didier 1 collaboration

Raphaëlle Caillerez 1 collaboration

Sébastien Carrier 1 collaboration

Claudia Marinangeli 1 collaboration

Valérie Vingtdeux 1 collaboration

Sarah Lieger 1 collaboration

Susanna Schraen-Maschke 1 collaboration

Pascal Steullet 1 collaboration

Mathieu Pachoud 1 collaboration

Mathischan Maheswaran 1 collaboration

Catherine Pythoud 1 collaboration

Maria Rey 1 collaboration

Kim Q Do 1 collaboration

Paola Bezzi 1 collaboration

Geneviève Leuba 1 collaboration

Marine Denechaud 1 collaboration

Sarah Geurs 1 collaboration

Thomas Comptdaer 1 collaboration

Alejandro Garcia-Núñez 1 collaboration

Louis-Adrien Pechereau 1 collaboration

Yannick Vermeiren 1 collaboration

Peter P De Deyn 1 collaboration

Claude-Alain Maurage 1 collaboration

Michiel Vanderhaegen 1 collaboration

Sebastiaan Vanuytven 1 collaboration

Bruno Lefebvre 1 collaboration

Elke Bogaert 1 collaboration

Thierry Voet 1 collaboration

Bart Dermaut 1 collaboration

Marie-Christine Galas 1 collaboration

Valentin Zufferey 1 collaboration

Lucas Culebras 1 collaboration

Sylvain Perriot 1 collaboration

Renaud Du Pasquier 1 collaboration

Margarida C Simões 1 collaboration

Lea ElHajjar 1 collaboration

Marine Nguyen 1 collaboration

Cláudio M Gomes 1 collaboration