Ryan H Gumpper

Affiliations

Department of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

ORCID: https://orcid.org/0000-0003-1309-3069

Publications (13)

Chemistry/structural biology of psychedelic drugs and their receptor(s).

British journal of pharmacology

Avec: Ryan H Gumpper , David E Nichols

Constraints of Viral RNA Synthesis on Codon Usage of Negative-Strand RNA Virus.

Journal of virology

Avec: Ryan H Gumpper , Weike Li , Ming Luo

Structure, function and pharmacology of human itch GPCRs.

Nature

Avec: Can Cao , Hye Jin Kang , Isha Singh , He Chen , Chengwei Zhang , Wenlei Ye , Byron W Hayes , Jing Liu , Ryan H Gumpper , Brian J Bender , Samuel T Slocum , Brian E Krumm , Katherine Lansu , John D McCorvy , Wesley K Kroeze , Justin G English , Jeffrey F DiBerto , Reid H J Olsen , Xi-Ping Huang , Shicheng Zhang , Yongfeng Liu , Kuglae Kim , Joel Karpiak , Lily Y Jan , Soman N Abraham , Jian Jin , Brian K Shoichet , Jonathan F Fay , Bryan L Roth

Psychedelics: preclinical insights provide directions for future research.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Avec: Ryan H Gumpper , Bryan L Roth

G-Protein Peptidomimetics Stabilize GPCR Active State Conformations.

Trends in pharmacological sciences

Avec: Ryan H Gumpper , Bryan L Roth

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT

Cell reports

Avec: Ryan H Gumpper , Jonathan F Fay , Bryan L Roth

Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.

Nature chemical biology

Avec: Yongfeng Liu , Can Cao , Xi-Ping Huang , Ryan H Gumpper , Moira M Rachman , Sheng-Luen Shih , Brian E Krumm , Shicheng Zhang , Brian K Shoichet , Jonathan F Fay , Bryan L Roth

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.

Neuron

Avec: Can Cao , Ximena Barros-Álvarez , Shicheng Zhang , Kuglae Kim , Marc A Dämgen , Ouliana Panova , Carl-Mikael Suomivuori , Jonathan F Fay , Xiaofang Zhong , Brian E Krumm , Ryan H Gumpper , Alpay B Seven , Michael J Robertson , Nevan J Krogan , Ruth Hüttenhain , David E Nichols , Ron O Dror , Georgios Skiniotis , Bryan L Roth

SnapShot: Psychedelics and serotonin receptor signaling.

Cell

Avec: Ryan H Gumpper , Bryan L Roth

Bitter taste receptor activation by cholesterol and an intracellular tastant.

Nature

Avec: Yoojoong Kim , Ryan H Gumpper , Yongfeng Liu , D Dewran Kocak , Yan Xiong , Can Cao , Zhijie Deng , Brian E Krumm , Manish K Jain , Shicheng Zhang , Jian Jin , Bryan L Roth

DNA selection by the master transcription factor PU.1.

Cell reports

Avec: J Ross Terrell , Samuel J Taylor , Amelia L Schneider , Yue Lu , Tyler N Vernon , Suela Xhani , Ryan H Gumpper , Ming Luo , W David Wilson , Ulrich Steidl , Gregory M K Poon

Psychedelics as Transformative Therapeutics.

The American journal of psychiatry

Avec: Bryan L Roth , Ryan H Gumpper

Molecular basis for selective activation of DREADD-based chemogenetics.

Nature

Avec: Shicheng Zhang , Ryan H Gumpper , Xi-Ping Huang , Yongfeng Liu , Brian E Krumm , Can Cao , Jonathan F Fay , Bryan L Roth

Réseau de co-auteurs

Bryan L Roth 10 collaborations

Can Cao 5 collaborations

Brian E Krumm 5 collaborations

Shicheng Zhang 5 collaborations

Jonathan F Fay 5 collaborations

Yongfeng Liu 4 collaborations

Xi-Ping Huang 3 collaborations

David E Nichols 2 collaborations

Ming Luo 2 collaborations

Kuglae Kim 2 collaborations

Jian Jin 2 collaborations

Brian K Shoichet 2 collaborations

Weike Li 1 collaboration

Hye Jin Kang 1 collaboration

Isha Singh 1 collaboration

He Chen 1 collaboration

Chengwei Zhang 1 collaboration

Wenlei Ye 1 collaboration

Byron W Hayes 1 collaboration

Jing Liu 1 collaboration

Brian J Bender 1 collaboration

Samuel T Slocum 1 collaboration

Katherine Lansu 1 collaboration

John D McCorvy 1 collaboration

Wesley K Kroeze 1 collaboration

Justin G English 1 collaboration

Jeffrey F DiBerto 1 collaboration

Reid H J Olsen 1 collaboration

Joel Karpiak 1 collaboration

Lily Y Jan 1 collaboration

Soman N Abraham 1 collaboration

Moira M Rachman 1 collaboration

Sheng-Luen Shih 1 collaboration

Ximena Barros-Álvarez 1 collaboration

Marc A Dämgen 1 collaboration

Ouliana Panova 1 collaboration

Carl-Mikael Suomivuori 1 collaboration

Xiaofang Zhong 1 collaboration

Alpay B Seven 1 collaboration

Michael J Robertson 1 collaboration

Nevan J Krogan 1 collaboration

Ruth Hüttenhain 1 collaboration

Ron O Dror 1 collaboration

Georgios Skiniotis 1 collaboration

Yoojoong Kim 1 collaboration

D Dewran Kocak 1 collaboration

Yan Xiong 1 collaboration

Zhijie Deng 1 collaboration

Manish K Jain 1 collaboration

J Ross Terrell 1 collaboration

Samuel J Taylor 1 collaboration

Amelia L Schneider 1 collaboration

Yue Lu 1 collaboration

Tyler N Vernon 1 collaboration

Suela Xhani 1 collaboration

W David Wilson 1 collaboration

Ulrich Steidl 1 collaboration

Gregory M K Poon 1 collaboration