Rob S Sellar

Affiliations

Department of Haematology, UCL Cancer Institute, London, UK; Dana-Farber Cancer Institute, Boston, MA, USA; Broad Institute of Harvard and MIT, Cambridge, MA, USA.

Publications (10)

The clonal hematopoiesis mutation Jak2

International journal of cardiology

Avec: Roberto Molinaro , Rob S Sellar , Amélie Vromman , Grasiele Sausen , Eduardo Folco , Galina K Sukhova , Marie E McConke , Claudia Corbo , Benjamin L Ebert , Peter Libby

Clonal haematopoiesis and risk of chronic liver disease.

Nature

Avec: Waihay J Wong , Connor Emdin , Alexander G Bick , Seyedeh M Zekavat , Abhishek Niroula , James P Pirruccello , Laura Dichtel , Gabriel Griffin , Md Mesbah Uddin , Christopher J Gibson , Veronica Kovalcik , Amy E Lin , Marie E McConkey , Amelie Vromman , Rob S Sellar , Peter G Kim , Mridul Agrawal , Joshua Weinstock , Michelle T Long , Bing Yu , Rajarshi Banerjee , Rowan C Nicholls , Andrea Dennis , Matt Kelly , Po-Ru Loh , Steve McCarroll , Eric Boerwinkle , Ramachandran S Vasan , Siddhartha Jaiswal , Andrew D Johnson , Raymond T Chung , Kathleen Corey , Daniel Levy , Christie Ballantyne , Auteur inconnu , Benjamin L Ebert , Pradeep Natarajan

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.

Nature

Avec: Mikołaj Słabicki , Zuzanna Kozicka , Georg Petzold , Yen-Der Li , Manisha Manojkumar , Richard D Bunker , Katherine A Donovan , Quinlan L Sievers , Jonas Koeppel , Dakota Suchyta , Adam S Sperling , Emma C Fink , Jessica A Gasser , Li R Wang , Steven M Corsello , Rob S Sellar , Max Jan , Dennis Gillingham , Claudia Scholl , Stefan Fröhling , Todd R Golub , Eric S Fischer , Nicolas H Thomä , Benjamin L Ebert

Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial.

Blood

Avec: Sylvie D Freeman , Abin Thomas , Ian Thomas , Robert K Hills , Paresh Vyas , Amanda Gilkes , Marlen Metzner , Niels Asger Jakobsen , Alison Kennedy , Rachel Moore , Nuria Marquez Almuina , Sarah Burns , Sophie King , Georgia Andrew , Kathleen M E Gallagher , Rob S Sellar , Paul Cahalin , Duruta Weber , Mike Dennis , Priyanka Mehta , Steven Knapper , Nigel H Russell

Molecular MRD is strongly prognostic in patients with NPM1-mutated AML receiving venetoclax-based non-intensive therapy.

Blood

Avec: Jad Othman , Ing Soo Tiong , Jenny O'Nions , Mike Dennis , Katya Mokretar , Adam Ivey , Michael James Austin , Annie-Louise Latif , Mariam Amer , Wei Yee Chan , Charles R Crawley , Francesca Crolla , Joe Wilson Cross , Raymond Dang , Johnathon Elliot , Chun Yew Fong , Sofia Galli , Paolo Gallipoli , Francesca Hogan , Pallavi Kalkur , Anjum Bashir Khan , Pramila Krishnamurthy , John Laurie , Sun Loo , Scott Marshall , Priyanka Mehta , Vidhya Murthy , Sateesh Nagumantry , Srinivas Pillai , Nicola Potter , Rob S Sellar , Tom Taylor , Rui Zhao , Nigel H Russell , Andrew H Wei , Richard Dillon

Avadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies.

Blood cancer discovery

Avec: Aline Renneville , Jessica A Gasser , Daniel E Grinshpun , Pierre M Jean Beltran , Namrata D Udeshi , Mary E Matyskiela , Thomas Clayton , Marie McConkey , Kaushik Viswanathan , Alexander Tepper , Andrew A Guirguis , Rob S Sellar , Sophie Cotteret , Christophe Marzac , Véronique Saada , Stéphane De Botton , Jean-Jacques Kiladjian , Jean-Michel Cayuela , Mark Rolfe , Philip P Chamberlain , Steven A Carr , Benjamin L Ebert

The emerging role of targeted protein degradation to treat and study cancer.

The Journal of pathology

Avec: Maximillian H Brodermann , Elizabeth K Henderson , Rob S Sellar

Outcomes with single-agent gilteritinib for relapsed or refractory FLT3-mutant AML after contemporary induction therapy.

Blood advances

Avec: Jad Othman , Angela Hwang , Maximillian Hugo Brodermann , Islam Abdallah , Kayleigh McCloskey , Paolo Gallipoli , Georgina Clarke , Raymond Dang , Jennifer Vidler , Pramila Krishnamurthy , Faisal Basheer , Anne-Louise Latif , Renuka Palanicawandar , Tom Taylor , Asra Khan , Victoria Campbell , Francesca Hogan , Alexandros Kanellopoulos , Kathryn Fleming , Angela Collins , Christopher Dalley , Justin Loke , Scott Marshall , David Taussig , Sreetharan Munisamy , Eleana Loizou , Heba Yassin , Mike Dennis , Rui Zhao , Edward Belsham , Duncan Murray , Nicole Fowler , Jenny O'Nions , Anjum Bashir Khan , Rob S Sellar , Richard James Dillon

Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs.

Blood

Avec: Adam S Sperling , Michael Burgess , Hasmik Keshishian , Jessica A Gasser , Shruti Bhatt , Max Jan , Mikołaj Słabicki , Rob S Sellar , Emma C Fink , Peter G Miller , Brian J Liddicoat , Quinlan L Sievers , Rohan Sharma , Dylan N Adams , Elyse A Olesinski , Mariateresa Fulciniti , Namrata D Udeshi , Eric Kuhn , Anthony Letai , Nikhil C Munshi , Steven A Carr , Benjamin L Ebert

Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.

The Journal of clinical investigation

Avec: Rob S Sellar , Adam S Sperling , Mikołaj Słabicki , Jessica A Gasser , Marie E McConkey , Katherine A Donovan , Nada Mageed , Dylan N Adams , Charles Zou , Peter G Miller , Ravi K Dutta , Steffen Boettcher , Amy E Lin , Brittany Sandoval , Vanessa A Quevedo Barrios , Veronica Kovalcik , Jonas Koeppel , Elizabeth K Henderson , Emma C Fink , Lu Yang , Anthony Chan , Sheela Pangeni Pokharel , Erik J Bergstrom , Rajan Burt , Namrata D Udeshi , Steven A Carr , Eric S Fischer , Chun-Wei Chen , Benjamin L Ebert

Réseau de co-auteurs

Benjamin L Ebert 6 collaborations

Jessica A Gasser 4 collaborations

Mikołaj Słabicki 3 collaborations

Adam S Sperling 3 collaborations

Emma C Fink 3 collaborations

Mike Dennis 3 collaborations

Namrata D Udeshi 3 collaborations

Steven A Carr 3 collaborations

Veronica Kovalcik 2 collaborations

Amy E Lin 2 collaborations

Marie E McConkey 2 collaborations

Katherine A Donovan 2 collaborations

Quinlan L Sievers 2 collaborations

Jonas Koeppel 2 collaborations

Max Jan 2 collaborations

Eric S Fischer 2 collaborations

Priyanka Mehta 2 collaborations

Nigel H Russell 2 collaborations

Jad Othman 2 collaborations

Jenny O'Nions 2 collaborations

Raymond Dang 2 collaborations

Paolo Gallipoli 2 collaborations

Francesca Hogan 2 collaborations

Anjum Bashir Khan 2 collaborations

Pramila Krishnamurthy 2 collaborations

Scott Marshall 2 collaborations

Tom Taylor 2 collaborations

Rui Zhao 2 collaborations

Elizabeth K Henderson 2 collaborations

Peter G Miller 2 collaborations

Dylan N Adams 2 collaborations

Roberto Molinaro 1 collaboration

Amélie Vromman 1 collaboration

Grasiele Sausen 1 collaboration

Eduardo Folco 1 collaboration

Galina K Sukhova 1 collaboration

Marie E McConke 1 collaboration

Claudia Corbo 1 collaboration

Peter Libby 1 collaboration

Waihay J Wong 1 collaboration

Connor Emdin 1 collaboration

Alexander G Bick 1 collaboration

Seyedeh M Zekavat 1 collaboration

Abhishek Niroula 1 collaboration

James P Pirruccello 1 collaboration

Laura Dichtel 1 collaboration

Gabriel Griffin 1 collaboration

Md Mesbah Uddin 1 collaboration

Christopher J Gibson 1 collaboration

Amelie Vromman 1 collaboration

Peter G Kim 1 collaboration

Mridul Agrawal 1 collaboration

Joshua Weinstock 1 collaboration

Michelle T Long 1 collaboration

Bing Yu 1 collaboration

Rajarshi Banerjee 1 collaboration

Rowan C Nicholls 1 collaboration

Andrea Dennis 1 collaboration

Matt Kelly 1 collaboration

Po-Ru Loh 1 collaboration

Steve McCarroll 1 collaboration

Eric Boerwinkle 1 collaboration

Ramachandran S Vasan 1 collaboration

Siddhartha Jaiswal 1 collaboration

Andrew D Johnson 1 collaboration

Raymond T Chung 1 collaboration

Kathleen Corey 1 collaboration

Daniel Levy 1 collaboration

Christie Ballantyne 1 collaboration

None None 1 collaboration

Pradeep Natarajan 1 collaboration

Zuzanna Kozicka 1 collaboration

Georg Petzold 1 collaboration

Yen-Der Li 1 collaboration

Manisha Manojkumar 1 collaboration

Richard D Bunker 1 collaboration

Dakota Suchyta 1 collaboration

Li R Wang 1 collaboration

Steven M Corsello 1 collaboration

Dennis Gillingham 1 collaboration

Claudia Scholl 1 collaboration

Stefan Fröhling 1 collaboration

Todd R Golub 1 collaboration

Nicolas H Thomä 1 collaboration

Sylvie D Freeman 1 collaboration

Abin Thomas 1 collaboration

Ian Thomas 1 collaboration

Robert K Hills 1 collaboration

Paresh Vyas 1 collaboration

Amanda Gilkes 1 collaboration

Marlen Metzner 1 collaboration

Niels Asger Jakobsen 1 collaboration

Alison Kennedy 1 collaboration

Rachel Moore 1 collaboration

Nuria Marquez Almuina 1 collaboration

Sarah Burns 1 collaboration

Sophie King 1 collaboration

Georgia Andrew 1 collaboration

Kathleen M E Gallagher 1 collaboration

Paul Cahalin 1 collaboration

Duruta Weber 1 collaboration

Steven Knapper 1 collaboration

Ing Soo Tiong 1 collaboration

Katya Mokretar 1 collaboration

Adam Ivey 1 collaboration

Michael James Austin 1 collaboration

Annie-Louise Latif 1 collaboration

Mariam Amer 1 collaboration

Wei Yee Chan 1 collaboration

Charles R Crawley 1 collaboration

Francesca Crolla 1 collaboration

Joe Wilson Cross 1 collaboration

Johnathon Elliot 1 collaboration

Chun Yew Fong 1 collaboration

Sofia Galli 1 collaboration

Pallavi Kalkur 1 collaboration

John Laurie 1 collaboration

Sun Loo 1 collaboration

Vidhya Murthy 1 collaboration

Sateesh Nagumantry 1 collaboration

Srinivas Pillai 1 collaboration

Nicola Potter 1 collaboration

Andrew H Wei 1 collaboration

Richard Dillon 1 collaboration

Aline Renneville 1 collaboration

Daniel E Grinshpun 1 collaboration

Pierre M Jean Beltran 1 collaboration

Mary E Matyskiela 1 collaboration

Thomas Clayton 1 collaboration

Marie McConkey 1 collaboration

Kaushik Viswanathan 1 collaboration

Alexander Tepper 1 collaboration

Andrew A Guirguis 1 collaboration

Sophie Cotteret 1 collaboration

Christophe Marzac 1 collaboration

Véronique Saada 1 collaboration

Stéphane De Botton 1 collaboration

Jean-Jacques Kiladjian 1 collaboration

Jean-Michel Cayuela 1 collaboration

Mark Rolfe 1 collaboration

Philip P Chamberlain 1 collaboration

Maximillian H Brodermann 1 collaboration

Angela Hwang 1 collaboration

Maximillian Hugo Brodermann 1 collaboration

Islam Abdallah 1 collaboration

Kayleigh McCloskey 1 collaboration

Georgina Clarke 1 collaboration

Jennifer Vidler 1 collaboration

Faisal Basheer 1 collaboration

Anne-Louise Latif 1 collaboration

Renuka Palanicawandar 1 collaboration

Asra Khan 1 collaboration

Victoria Campbell 1 collaboration

Alexandros Kanellopoulos 1 collaboration

Kathryn Fleming 1 collaboration

Angela Collins 1 collaboration

Christopher Dalley 1 collaboration

Justin Loke 1 collaboration

David Taussig 1 collaboration

Sreetharan Munisamy 1 collaboration

Eleana Loizou 1 collaboration

Heba Yassin 1 collaboration

Edward Belsham 1 collaboration

Duncan Murray 1 collaboration

Nicole Fowler 1 collaboration

Richard James Dillon 1 collaboration

Michael Burgess 1 collaboration

Hasmik Keshishian 1 collaboration

Shruti Bhatt 1 collaboration

Brian J Liddicoat 1 collaboration

Rohan Sharma 1 collaboration

Elyse A Olesinski 1 collaboration

Mariateresa Fulciniti 1 collaboration

Eric Kuhn 1 collaboration

Anthony Letai 1 collaboration

Nikhil C Munshi 1 collaboration

Nada Mageed 1 collaboration

Charles Zou 1 collaboration

Ravi K Dutta 1 collaboration

Steffen Boettcher 1 collaboration

Brittany Sandoval 1 collaboration

Vanessa A Quevedo Barrios 1 collaboration

Lu Yang 1 collaboration

Anthony Chan 1 collaboration

Sheela Pangeni Pokharel 1 collaboration

Erik J Bergstrom 1 collaboration

Rajan Burt 1 collaboration

Chun-Wei Chen 1 collaboration