Richard Possemato

Affiliations

Department of Pathology, New York University School of Medicine, New York, New York.

ORCID: 0000-0002-2401-0030

Publications (12)

Epigenetic CRISPR Screens Identify

Cancer research

Avec: Fei Li , Wai-Lung Ng , Troy A Luster , Hai Hu , Vladislav O Sviderskiy , Catríona M Dowling , Kate E R Hollinshead , Paula Zouitine , Hua Zhang , Qingyuan Huang , Michela Ranieri , Wei Wang , Zhaoyuan Fang , Ting Chen , Jiehui Deng , Kai Zhao , Hon-Cheong So , Alireza Khodadadi-Jamayran , Mousheng Xu , Angeliki Karatza , Val Pyon , Shuai Li , Yuanwang Pan , Kristen Labbe , Christina Almonte , John T Poirier , George Miller , Richard Possemato , Jun Qi , Kwok-Kin Wong

Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5.

Science advances

Avec: Erdem M Terzi , Vladislav O Sviderskiy , Samantha W Alvarez , Gabrielle C Whiten , Richard Possemato

PhosphoDisco: A Toolkit for Co-regulated Phosphorylation Module Discovery in Phosphoproteomic Data.

Molecular & cellular proteomics : MCP

Avec: Tobias Schraink , Lili Blumenberg , Grant Hussey , Sabrina George , Brecca Miller , Nithu Mathew , Tania J González-Robles , Vladislav Sviderskiy , Thales Papagiannakopoulos , Richard Possemato , David Fenyö , Kelly V Ruggles

Iron, Copper, and Selenium: Cancer's Thing for Redox Bling.

Cold Spring Harbor perspectives in medicine

Avec: Erdem M Terzi , Richard Possemato

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability.

Cell reports

Avec: Niklas Ravn-Boess , Nainita Roy , Takamitsu Hattori , Devin Bready , Hayley Donaldson , Christopher Lawson , Cathryn Lapierre , Aryeh Korman , Tori Rodrick , Enze Liu , Joshua D Frenster , Gabriele Stephan , Jordan Wilcox , Alexis D Corrado , Julia Cai , Rebecca Ronnen , Shuai Wang , Sara Haddock , Jonathan Sabio Ortiz , Orin Mishkit , Alireza Khodadadi-Jamayran , Aris Tsirigos , David Fenyö , David Zagzag , Julia Drube , Carsten Hoffmann , Fabiana Perna , Drew R Jones , Richard Possemato , Akiko Koide , Shohei Koide , Christopher Y Park , Dimitris G Placantonakis

Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4.

Cell reports

Avec: Rebecca L McIntyre , Marte Molenaars , Bauke V Schomakers , Arwen W Gao , Rashmi Kamble , Aldo Jongejan , Michel van Weeghel , André B P van Kuilenburg , Richard Possemato , Riekelt H Houtkooper , Georges E Janssens

Acute inhibition of iron-sulfur cluster biosynthesis disrupts metabolic flexibility in mice.

bioRxiv : the preprint server for biology

Avec: Marte Molenaars , Hannan Mir , Samantha W Alvarez , Lakshmi Arivazhagan , Carolina Rosselot , Di Zhan , Christopher Y Park , Adolfo Garcia-Ocana , Ann Marie Schmidt , Richard Possemato

Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle.

Nature metabolism

Avec: Jong Shin , Hannan Mir , Maaz A Khurram , Kenji M Fujihara , Brian D Dynlacht , Timothy J Cardozo , Richard Possemato

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy.

Cell

Avec: Lin Wu , Kate E R Hollinshead , Yuhan Hao , Christy Au , Lina Kroehling , Charles Ng , Woan-Yu Lin , Dayi Li , Hernandez Moura Silva , Jong Shin , Juan J Lafaille , Richard Possemato , Michael E Pacold , Thales Papagiannakopoulos , Alec C Kimmelman , Rahul Satija , Dan R Littman

KRAS4A directly regulates hexokinase 1.

Nature

Avec: Caroline R Amendola , James P Mahaffey , Seth J Parker , Ian M Ahearn , Wei-Ching Chen , Mo Zhou , Helen Court , Jie Shi , Sebastian L Mendoza , Michael J Morten , Eli Rothenberg , Eyal Gottlieb , Youssef Z Wadghiri , Richard Possemato , Stevan R Hubbard , Allan Balmain , Alec C Kimmelman , Mark R Philips

Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε.

Molecular cell

Avec: Vladislav O Sviderskiy , Lili Blumenberg , Elizabeth Gorodetsky , Triantafyllia R Karakousi , Nicole Hirsh , Samantha W Alvarez , Erdem M Terzi , Efiyenia Kaparos , Gabrielle C Whiten , Shakirah Ssebyala , Peter Tonzi , Hannan Mir , Benjamin G Neel , Tony T Huang , Sylvia Adams , Kelly V Ruggles , Richard Possemato

SHORT CHAIN FATTY ACIDS MITIGATE OSTEOCLAST-MEDIATED ARTHRITIC BONE REMODELLING.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Katharine Lu Yang , Briana J Mullins , Alannah Lejeune , Ellie Ivanova , Jong Shin , Sofia Bajwa , Richard Possemato , Ken Cadwell , Jose U Scher , Sergei B Koralov

Réseau de co-auteurs

Vladislav O Sviderskiy 3 collaborations

Erdem M Terzi 3 collaborations

Samantha W Alvarez 3 collaborations

Hannan Mir 3 collaborations

Jong Shin 3 collaborations

Kate E R Hollinshead 2 collaborations

Alireza Khodadadi-Jamayran 2 collaborations

Gabrielle C Whiten 2 collaborations

Lili Blumenberg 2 collaborations

Thales Papagiannakopoulos 2 collaborations

David Fenyö 2 collaborations

Kelly V Ruggles 2 collaborations

Christopher Y Park 2 collaborations

Marte Molenaars 2 collaborations

Alec C Kimmelman 2 collaborations

Fei Li 1 collaboration

Wai-Lung Ng 1 collaboration

Troy A Luster 1 collaboration

Hai Hu 1 collaboration

Catríona M Dowling 1 collaboration

Paula Zouitine 1 collaboration

Hua Zhang 1 collaboration

Qingyuan Huang 1 collaboration

Michela Ranieri 1 collaboration

Wei Wang 1 collaboration

Zhaoyuan Fang 1 collaboration

Ting Chen 1 collaboration

Jiehui Deng 1 collaboration

Kai Zhao 1 collaboration

Hon-Cheong So 1 collaboration

Mousheng Xu 1 collaboration

Angeliki Karatza 1 collaboration

Val Pyon 1 collaboration

Shuai Li 1 collaboration

Yuanwang Pan 1 collaboration

Kristen Labbe 1 collaboration

Christina Almonte 1 collaboration

John T Poirier 1 collaboration

George Miller 1 collaboration

Jun Qi 1 collaboration

Kwok-Kin Wong 1 collaboration

Tobias Schraink 1 collaboration

Grant Hussey 1 collaboration

Sabrina George 1 collaboration

Brecca Miller 1 collaboration

Nithu Mathew 1 collaboration

Tania J González-Robles 1 collaboration

Vladislav Sviderskiy 1 collaboration

Niklas Ravn-Boess 1 collaboration

Nainita Roy 1 collaboration

Takamitsu Hattori 1 collaboration

Devin Bready 1 collaboration

Hayley Donaldson 1 collaboration

Christopher Lawson 1 collaboration

Cathryn Lapierre 1 collaboration

Aryeh Korman 1 collaboration

Tori Rodrick 1 collaboration

Enze Liu 1 collaboration

Joshua D Frenster 1 collaboration

Gabriele Stephan 1 collaboration

Jordan Wilcox 1 collaboration

Alexis D Corrado 1 collaboration

Julia Cai 1 collaboration

Rebecca Ronnen 1 collaboration

Shuai Wang 1 collaboration

Sara Haddock 1 collaboration

Jonathan Sabio Ortiz 1 collaboration

Orin Mishkit 1 collaboration

Aris Tsirigos 1 collaboration

David Zagzag 1 collaboration

Julia Drube 1 collaboration

Carsten Hoffmann 1 collaboration

Fabiana Perna 1 collaboration

Drew R Jones 1 collaboration

Akiko Koide 1 collaboration

Shohei Koide 1 collaboration

Dimitris G Placantonakis 1 collaboration

Rebecca L McIntyre 1 collaboration

Bauke V Schomakers 1 collaboration

Arwen W Gao 1 collaboration

Rashmi Kamble 1 collaboration

Aldo Jongejan 1 collaboration

Michel van Weeghel 1 collaboration

André B P van Kuilenburg 1 collaboration

Riekelt H Houtkooper 1 collaboration

Georges E Janssens 1 collaboration

Lakshmi Arivazhagan 1 collaboration

Carolina Rosselot 1 collaboration

Di Zhan 1 collaboration

Adolfo Garcia-Ocana 1 collaboration

Ann Marie Schmidt 1 collaboration

Maaz A Khurram 1 collaboration

Kenji M Fujihara 1 collaboration

Brian D Dynlacht 1 collaboration

Timothy J Cardozo 1 collaboration

Lin Wu 1 collaboration

Yuhan Hao 1 collaboration

Christy Au 1 collaboration

Lina Kroehling 1 collaboration

Charles Ng 1 collaboration

Woan-Yu Lin 1 collaboration

Dayi Li 1 collaboration

Hernandez Moura Silva 1 collaboration

Juan J Lafaille 1 collaboration

Michael E Pacold 1 collaboration

Rahul Satija 1 collaboration

Dan R Littman 1 collaboration

Caroline R Amendola 1 collaboration

James P Mahaffey 1 collaboration

Seth J Parker 1 collaboration

Ian M Ahearn 1 collaboration

Wei-Ching Chen 1 collaboration

Mo Zhou 1 collaboration

Helen Court 1 collaboration

Jie Shi 1 collaboration

Sebastian L Mendoza 1 collaboration

Michael J Morten 1 collaboration

Eli Rothenberg 1 collaboration

Eyal Gottlieb 1 collaboration

Youssef Z Wadghiri 1 collaboration

Stevan R Hubbard 1 collaboration

Allan Balmain 1 collaboration

Mark R Philips 1 collaboration

Elizabeth Gorodetsky 1 collaboration

Triantafyllia R Karakousi 1 collaboration

Nicole Hirsh 1 collaboration

Efiyenia Kaparos 1 collaboration

Shakirah Ssebyala 1 collaboration

Peter Tonzi 1 collaboration

Benjamin G Neel 1 collaboration

Tony T Huang 1 collaboration

Sylvia Adams 1 collaboration

Katharine Lu Yang 1 collaboration

Briana J Mullins 1 collaboration

Alannah Lejeune 1 collaboration

Ellie Ivanova 1 collaboration

Sofia Bajwa 1 collaboration

Ken Cadwell 1 collaboration

Jose U Scher 1 collaboration

Sergei B Koralov 1 collaboration