Raphael Heilig

Affiliations

Discovery Proteomics Facility, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, United Kingdom.

Publications (11)

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.

Nature communications

Avec: José Carlos Santos , Dave Boucher , Larisa Kapinos Schneider , Benjamin Demarco , Marisa Dilucca , Kateryna Shkarina , Rosalie Heilig , Kaiwen W Chen , Roderick Y H Lim , Petr Broz

Glycosylated Siglec-6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclampsia placentas.

Biochemical and biophysical research communications

Avec: Toluwalase Awoyemi , Dionne Tannetta , Wei Zhang , Neva Kandzija , Carolina Motta-Mejia , Roman Fischer , Raphael Heilig , Sina Raiss , Christopher Redman , Manu Vatish

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response.

Science translational medicine

Avec: Yuxin Mi , Katie L Burnham , Philip D Charles , Raphael Heilig , Iolanda Vendrell , Justin Whalley , Hew D Torrance , David B Antcliffe , Shaun M May , Matt J Neville , Georgina Berridge , Paula Hutton , Cyndi G Geoghegan , Jayachandran Radhakrishnan , Alexey I Nesvizhskii , Fengchao Yu , Auteur inconnu , Emma E Davenport , Stuart McKechnie , Roger Davies , David J P O'Callaghan , Parind Patel , Ana G Del Arroyo , Fredrik Karpe , Anthony C Gordon , Gareth L Ackland , Charles J Hinds , Roman Fischer , Julian C Knight

Identification of cellular retinoic acid binding protein 2 (CRABP2) as downstream target of nuclear factor I/X (NFIX): implications for skeletal dysplasia syndromes.

JBMR plus

Avec: Kreepa G Kooblall , Mark Stevenson , Raphael Heilig , Michelle Stewart , Benjamin Wright , Helen Lockstone , David Buck , Roman Fischer , Sara Wells , Kate E Lines , Lydia Teboul , Raoul C Hennekam , Rajesh V Thakker

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.

Basic research in cardiology

Avec: He Jiang , Charlotte Hooper , Matthew Kelly , Violetta Steeples , Jillian N Simon , Julia Beglov , Amar J Azad , Lisa Leinhos , Pauline Bennett , Elisabeth Ehler , Jacinta I Kalisch-Smith , Duncan B Sparrow , Roman Fischer , Raphael Heilig , Henrik Isackson , Mehroz Ehsan , Giannino Patone , Norbert Huebner , Benjamin Davies , Hugh Watkins , Katja Gehmlich

Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase.

The Biochemical journal

Avec: Zhuoyao Chen , Jinwei Zhang , Adrián R Murillo-de-Ozores , María Castañeda-Bueno , Francesca D'Amico , Raphael Heilig , Charlotte E Manning , Fiona J Sorrell , Vincenzo D'Angiolella , Roman Fischer , Monique P C Mulder , Gerardo Gamba , Dario R Alessi , Alex N Bullock

A novel method to quantify fibrin-fibrin and fibrin-α

Journal of thrombosis and haemostasis : JTH

Avec: Gael B Morrow , Sarah Flannery , Philip D Charles , Raphael Heilig , Timea Feller , Zoe McQuilten , Elizabeth Wake , Robert A S Ariens , James Winearls , Nicola J Mutch , Roman Fischer , Mike A Laffan , Nicola Curry

Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.

Life science alliance

Avec: Rosalie Heilig , Marisa Dilucca , Dave Boucher , Kaiwen W Chen , Dora Hancz , Benjamin Demarco , Kateryna Shkarina , Petr Broz

Characterization of exosomes in peritoneal fluid of endometriosis patients.

Fertility and sterility

Avec: Hannah M Nazri , Maria Imran , Roman Fischer , Raphael Heilig , Sanjiv Manek , Rebecca A Dragovic , Benedikt M Kessler , Krina T Zondervan , Thomas T Tapmeier , Christian M Becker

ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context.

Frontiers in chemistry

Avec: Hannah B L Jones , Raphael Heilig , Roman Fischer , Benedikt M Kessler , Adán Pinto-Fernández

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage.

Developmental cell

Avec: Kai Cao , Joel S Riley , Rosalie Heilig , Alfredo E Montes-Gómez , Esmee Vringer , Kevin Berthenet , Catherine Cloix , Yassmin Elmasry , David G Spiller , Gabriel Ichim , Kirsteen J Campbell , Andrew P Gilmore , Stephen W G Tait

Réseau de co-auteurs

Roman Fischer 8 collaborations

Rosalie Heilig 3 collaborations

Dave Boucher 2 collaborations

Benjamin Demarco 2 collaborations

Marisa Dilucca 2 collaborations

Kateryna Shkarina 2 collaborations

Kaiwen W Chen 2 collaborations

Petr Broz 2 collaborations

Philip D Charles 2 collaborations

Benedikt M Kessler 2 collaborations

José Carlos Santos 1 collaboration

Larisa Kapinos Schneider 1 collaboration

Roderick Y H Lim 1 collaboration

Toluwalase Awoyemi 1 collaboration

Dionne Tannetta 1 collaboration

Wei Zhang 1 collaboration

Neva Kandzija 1 collaboration

Carolina Motta-Mejia 1 collaboration

Sina Raiss 1 collaboration

Christopher Redman 1 collaboration

Manu Vatish 1 collaboration

Yuxin Mi 1 collaboration

Katie L Burnham 1 collaboration

Iolanda Vendrell 1 collaboration

Justin Whalley 1 collaboration

Hew D Torrance 1 collaboration

David B Antcliffe 1 collaboration

Shaun M May 1 collaboration

Matt J Neville 1 collaboration

Georgina Berridge 1 collaboration

Paula Hutton 1 collaboration

Cyndi G Geoghegan 1 collaboration

Jayachandran Radhakrishnan 1 collaboration

Alexey I Nesvizhskii 1 collaboration

Fengchao Yu 1 collaboration

None None 1 collaboration

Emma E Davenport 1 collaboration

Stuart McKechnie 1 collaboration

Roger Davies 1 collaboration

David J P O'Callaghan 1 collaboration

Parind Patel 1 collaboration

Ana G Del Arroyo 1 collaboration

Fredrik Karpe 1 collaboration

Anthony C Gordon 1 collaboration

Gareth L Ackland 1 collaboration

Charles J Hinds 1 collaboration

Julian C Knight 1 collaboration

Kreepa G Kooblall 1 collaboration

Mark Stevenson 1 collaboration

Michelle Stewart 1 collaboration

Benjamin Wright 1 collaboration

Helen Lockstone 1 collaboration

David Buck 1 collaboration

Sara Wells 1 collaboration

Kate E Lines 1 collaboration

Lydia Teboul 1 collaboration

Raoul C Hennekam 1 collaboration

Rajesh V Thakker 1 collaboration

He Jiang 1 collaboration

Charlotte Hooper 1 collaboration

Matthew Kelly 1 collaboration

Violetta Steeples 1 collaboration

Jillian N Simon 1 collaboration

Julia Beglov 1 collaboration

Amar J Azad 1 collaboration

Lisa Leinhos 1 collaboration

Pauline Bennett 1 collaboration

Elisabeth Ehler 1 collaboration

Jacinta I Kalisch-Smith 1 collaboration

Duncan B Sparrow 1 collaboration

Henrik Isackson 1 collaboration

Mehroz Ehsan 1 collaboration

Giannino Patone 1 collaboration

Norbert Huebner 1 collaboration

Benjamin Davies 1 collaboration

Hugh Watkins 1 collaboration

Katja Gehmlich 1 collaboration

Zhuoyao Chen 1 collaboration

Jinwei Zhang 1 collaboration

Adrián R Murillo-de-Ozores 1 collaboration

María Castañeda-Bueno 1 collaboration

Francesca D'Amico 1 collaboration

Charlotte E Manning 1 collaboration

Fiona J Sorrell 1 collaboration

Vincenzo D'Angiolella 1 collaboration

Monique P C Mulder 1 collaboration

Gerardo Gamba 1 collaboration

Dario R Alessi 1 collaboration

Alex N Bullock 1 collaboration

Gael B Morrow 1 collaboration

Sarah Flannery 1 collaboration

Timea Feller 1 collaboration

Zoe McQuilten 1 collaboration

Elizabeth Wake 1 collaboration

Robert A S Ariens 1 collaboration

James Winearls 1 collaboration

Nicola J Mutch 1 collaboration

Mike A Laffan 1 collaboration

Nicola Curry 1 collaboration

Dora Hancz 1 collaboration

Hannah M Nazri 1 collaboration

Maria Imran 1 collaboration

Sanjiv Manek 1 collaboration

Rebecca A Dragovic 1 collaboration

Krina T Zondervan 1 collaboration

Thomas T Tapmeier 1 collaboration

Christian M Becker 1 collaboration

Hannah B L Jones 1 collaboration

Adán Pinto-Fernández 1 collaboration

Kai Cao 1 collaboration

Joel S Riley 1 collaboration

Alfredo E Montes-Gómez 1 collaboration

Esmee Vringer 1 collaboration

Kevin Berthenet 1 collaboration

Catherine Cloix 1 collaboration

Yassmin Elmasry 1 collaboration

David G Spiller 1 collaboration

Gabriel Ichim 1 collaboration

Kirsteen J Campbell 1 collaboration

Andrew P Gilmore 1 collaboration

Stephen W G Tait 1 collaboration