Rémy Pedeux

Affiliations

Univ. Rennes, INSERM U1242, Chemistry Oncogenesis Stress Signaling (COSS), CLCC Eugène Marquis, 35042 Rennes, France.

Publications (19)

Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation.

Cancers

Avec: Jérôme Archambeau , Alice Blondel , Rémy Pedeux

Newly identified tumor suppressor functions of ING proteins.

Current opinion in pharmacology

Avec: Léane Heliez , Charles Ricordel , Philippe Becuwe , Rémy Pedeux

Afatinib or Bevacizumab in combination with Osimertinib efficiently control tumor development in orthotopic murine models of non-small lung cancer.

PloS one

Avec: Ulrich Jarry , Megane Bostoen , Jérome Archambeau , Raphaël Pineau , Laura Chaillot , Florence Jouan , Hélène Solhi , Hugo Ferrari , Rémy Le Guevel , Valentine Mennessier , Hervé Lena , Romain Corre , Charles Ricordel , Thierry Guillaudeux , Rémy Pedeux

Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.

Life science alliance

Avec: Alexandra Papaioannou , Federica Centonze , Alice Metais , Marion Maurel , Luc Negroni , Matías Gonzalez-Quiroz , Sayyed Jalil Mahdizadeh , Gabriella Svensson , Ensieh Zare , Alice Blondel , Albert C Koong , Claudio Hetz , Rémy Pedeux , Michel L Tremblay , Leif A Eriksson , Eric Chevet

Characterization of the Peri-Membrane Fluorescence Phenomenon Allowing the Detection of Urothelial Tumor Cells in Urine.

Cancers

Avec: Charly Gutierrez , Xavier Pinson , Kathleen Jarnouen , Marine Charpentier , Raphael Pineau , Laëtitia Lallement , Rémy Pedeux

Preclinical Models for Acquired Resistance to Third-Generation EGFR Inhibitors in NSCLC: Functional Studies and Drug Combinations Used to Overcome Resistance.

Frontiers in oncology

Avec: Emna Mahfoudhi , Charles Ricordel , Gwendoline Lecuyer , Cécile Mouric , Hervé Lena , Rémy Pedeux

Regulat-INGs in tumors and diseases: Focus on ncRNAs.

Cancer letters

Avec: Marjorie Gournay , Mathieu Paineau , Jérôme Archambeau , Rémy Pedeux

ING2 tumor suppressive protein translocates into mitochondria and is involved in cellular metabolism homeostasis.

Oncogene

Avec: Charles Ricordel , Laura Chaillot , Alice Blondel , Jérôme Archambeau , Florence Jouan , Audrey Mouche , Marie Tiercin , Agnès Burel , Hervé Lena , Benoît Desrues , Thierry Guillaudeux , Rémy Pedeux

The Identification of New c-FLIP Inhibitors for Restoring Apoptosis in TRAIL-Resistant Cancer Cells.

Current issues in molecular biology

Avec: Katherine Yaacoub , Rémy Pedeux , Pierre Lafite , Ulrich Jarry , Samia Aci-Sèche , Pascal Bonnet , Richard Daniellou , Thierry Guillaudeux

Genomic characteristics and clinical significance of CD56+ circulating tumor cells in small cell lung cancer.

Scientific reports

Avec: Charles Ricordel , L Chaillot , E I Vlachavas , M Logotheti , A Jouannic , T Desvallees , G Lecuyer , M Aubry , G Kontogianni , C Mastrokalou , F Jouan , U Jarry , R Corre , Y Le Guen , T Guillaudeux , H Lena , A Chatziioannou , Rémy Pedeux

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.

Nature communications

Avec: Estefanie Dufey , José Manuel Bravo-San Pedro , Cristian Eggers , Matías González-Quiroz , Hery Urra , Alfredo I Sagredo , Denisse Sepulveda , Philippe Pihán , Amado Carreras-Sureda , Younis Hazari , Eduardo A Sagredo , Daniela Gutierrez , Cristian Valls , Alexandra Papaioannou , Diego Acosta-Alvear , Gisela Campos , Pedro M Domingos , Rémy Pedeux , Eric Chevet , Alejandra Alvarez , Patricio Godoy , Peter Walter , Alvaro Glavic , Guido Kroemer , Claudio Hetz

Radiosensitizing Fe-Au nanocapsules (hybridosomes®) increase survival of GL261 brain tumor-bearing mice treated by radiotherapy.

Nanomedicine : nanotechnology, biology, and medicine

Avec: Clément Goubault , Ulrich Jarry , Mégane Bostoën , Pierre-Antoine Éliat , Myrtil L Kahn , Rémy Pedeux , Thierry Guillaudeux , Fabienne Gauffre , Soizic Chevance

When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response.

Trends in cell biology

Avec: Matías González-Quiroz , Alice Blondel , Alfredo Sagredo , Claudio Hetz , Eric Chevet , Rémy Pedeux

Simple elaboration of drug-SPION nanocapsules (hybridosomes®) by solvent shifting: Effect of the drug molecular structure and concentration.

International journal of pharmaceutics

Avec: Déborah Iglicki , Myrtil L Kahn , Clément Goubault , Marielle Blot , Ulrich Jarry , Rémy Pedeux , Rémy Le Guével , Soizic Chevance , Fabienne Gauffre

Noninvasive Urine-Based Tests to Diagnose or Detect Recurrence of Bladder Cancer.

Cancers

Avec: Marine Charpentier , Charly Gutierrez , Thierry Guillaudeux , Grégory Verhoest , Rémy Pedeux

Exploiting ING2 Epigenetic Modulation as a Therapeutic Opportunity for Non-Small Cell Lung Cancer.

Cancers

Avec: Alice Blondel , Amine Benberghout , Rémy Pedeux , Charles Ricordel

ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks.

Cell death and differentiation

Avec: Audrey Mouche , Jérôme Archambeau , Charles Ricordel , Laura Chaillot , Nicolas Bigot , Thierry Guillaudeux , Muriel Grenon , Rémy Pedeux

Orthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment.

BMC cancer

Avec: Ulrich Jarry , Mégane Bostoën , Raphaël Pineau , Laura Chaillot , Valentine Mennessier , Pierre Montagne , Emilie Motte , Marjorie Gournay , Arnaud Le Goff , Thierry Guillaudeux , Rémy Pedeux

GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1.

Biochimica et biophysica acta. Gene regulatory mechanisms

Avec: Luciana L Almada , Kim Barroso , Sandhya Sen , Murat Toruner , Ashley N Sigafoos , Glancis L Raja Arul , David R Pease , Renzo E Vera , Rachel L O Olson , Holger W Auner , Rémy Pedeux , Juan L Iovanna , Eric Chevet , Martin E Fernandez-Zapico

Réseau de co-auteurs

Charles Ricordel 7 collaborations

Thierry Guillaudeux 7 collaborations

Alice Blondel 5 collaborations

Ulrich Jarry 5 collaborations

Jérôme Archambeau 4 collaborations

Laura Chaillot 4 collaborations

Eric Chevet 4 collaborations

Hervé Lena 3 collaborations

Claudio Hetz 3 collaborations

Raphaël Pineau 2 collaborations

Florence Jouan 2 collaborations

Valentine Mennessier 2 collaborations

Alexandra Papaioannou 2 collaborations

Charly Gutierrez 2 collaborations

Marine Charpentier 2 collaborations

Marjorie Gournay 2 collaborations

Audrey Mouche 2 collaborations

Matías González-Quiroz 2 collaborations

Clément Goubault 2 collaborations

Mégane Bostoën 2 collaborations

Myrtil L Kahn 2 collaborations

Fabienne Gauffre 2 collaborations

Soizic Chevance 2 collaborations

Léane Heliez 1 collaboration

Philippe Becuwe 1 collaboration

Megane Bostoen 1 collaboration

Jérome Archambeau 1 collaboration

Hélène Solhi 1 collaboration

Hugo Ferrari 1 collaboration

Rémy Le Guevel 1 collaboration

Romain Corre 1 collaboration

Federica Centonze 1 collaboration

Alice Metais 1 collaboration

Marion Maurel 1 collaboration

Luc Negroni 1 collaboration

Matías Gonzalez-Quiroz 1 collaboration

Sayyed Jalil Mahdizadeh 1 collaboration

Gabriella Svensson 1 collaboration

Ensieh Zare 1 collaboration

Albert C Koong 1 collaboration

Michel L Tremblay 1 collaboration

Leif A Eriksson 1 collaboration

Xavier Pinson 1 collaboration

Kathleen Jarnouen 1 collaboration

Raphael Pineau 1 collaboration

Laëtitia Lallement 1 collaboration

Emna Mahfoudhi 1 collaboration

Gwendoline Lecuyer 1 collaboration

Cécile Mouric 1 collaboration

Mathieu Paineau 1 collaboration

Marie Tiercin 1 collaboration

Agnès Burel 1 collaboration

Benoît Desrues 1 collaboration

Katherine Yaacoub 1 collaboration

Pierre Lafite 1 collaboration

Samia Aci-Sèche 1 collaboration

Pascal Bonnet 1 collaboration

Richard Daniellou 1 collaboration

L Chaillot 1 collaboration

E I Vlachavas 1 collaboration

M Logotheti 1 collaboration

A Jouannic 1 collaboration

T Desvallees 1 collaboration

G Lecuyer 1 collaboration

M Aubry 1 collaboration

G Kontogianni 1 collaboration

C Mastrokalou 1 collaboration

F Jouan 1 collaboration

U Jarry 1 collaboration

R Corre 1 collaboration

Y Le Guen 1 collaboration

T Guillaudeux 1 collaboration

H Lena 1 collaboration

A Chatziioannou 1 collaboration

Estefanie Dufey 1 collaboration

José Manuel Bravo-San Pedro 1 collaboration

Cristian Eggers 1 collaboration

Hery Urra 1 collaboration

Alfredo I Sagredo 1 collaboration

Denisse Sepulveda 1 collaboration

Philippe Pihán 1 collaboration

Amado Carreras-Sureda 1 collaboration

Younis Hazari 1 collaboration

Eduardo A Sagredo 1 collaboration

Daniela Gutierrez 1 collaboration

Cristian Valls 1 collaboration

Diego Acosta-Alvear 1 collaboration

Gisela Campos 1 collaboration

Pedro M Domingos 1 collaboration

Alejandra Alvarez 1 collaboration

Patricio Godoy 1 collaboration

Peter Walter 1 collaboration

Alvaro Glavic 1 collaboration

Guido Kroemer 1 collaboration

Pierre-Antoine Éliat 1 collaboration

Alfredo Sagredo 1 collaboration

Déborah Iglicki 1 collaboration

Marielle Blot 1 collaboration

Rémy Le Guével 1 collaboration

Grégory Verhoest 1 collaboration

Amine Benberghout 1 collaboration

Nicolas Bigot 1 collaboration

Muriel Grenon 1 collaboration

Pierre Montagne 1 collaboration

Emilie Motte 1 collaboration

Arnaud Le Goff 1 collaboration

Luciana L Almada 1 collaboration

Kim Barroso 1 collaboration

Sandhya Sen 1 collaboration

Murat Toruner 1 collaboration

Ashley N Sigafoos 1 collaboration

Glancis L Raja Arul 1 collaboration

David R Pease 1 collaboration

Renzo E Vera 1 collaboration

Rachel L O Olson 1 collaboration

Holger W Auner 1 collaboration

Juan L Iovanna 1 collaboration

Martin E Fernandez-Zapico 1 collaboration