Quentin Lecocq

Affiliations

Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences, Vrije Universiteit Brussel (VUB), 1090 Brussels, Belgium.

Publications (17)

Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production.

Vaccines

Avec: Katrijn Broos , Quentin Lecocq , Brenda De Keersmaecker , Geert Raes , Jurgen Corthals , Eva Lion , Kris Thielemans , Nick Devoogdt , Marleen Keyaerts , Karine Breckpot

Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use.

Biomolecules

Avec: Quentin Lecocq , Katty Zeven , Yannick De Vlaeminck , Sandrina Martens , Sam Massa , Cleo Goyvaerts , Geert Raes , Marleen Keyaerts , Karine Breckpot , Nick Devoogdt

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Yannick De Vlaeminck , Quentin Lecocq , Philippe Giron , Carlo Heirman , Xenia Geeraerts , Evangelia Bolli , Kiavash Movahedi , Sam Massa , Steve Schoonooghe , Kris Thielemans , Cleo Goyvaerts , Jo A Van Ginderachter , Karine Breckpot

Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Avec: Quentin Lecocq , Robin Maximilian Awad , Yannick De Vlaeminck , Wout de Mey , Thomas Ertveldt , Cleo Goyvaerts , Geert Raes , Kris Thielemans , Marleen Keyaerts , Nick Devoogdt , Karine Breckpot

Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry.

Pharmaceuticals (Basel, Switzerland)

Avec: Dora Mugoli Chigoho , Quentin Lecocq , Robin Maximilian Awad , Karine Breckpot , Nick Devoogdt , Marleen Keyaerts , Vicky Caveliers , Catarina Xavier , Jessica Bridoux

Phase I Study of [

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Avec: Odrade Gondry , Catarina Xavier , Laurens Raes , Johannes Heemskerk , Nick Devoogdt , Hendrik Everaert , Karine Breckpot , Quentin Lecocq , Lore Decoster , Christel Fontaine , Denis Schallier , Sandrine Aspeslagh , Ilse Vaneycken , Geert Raes , Jo A Van Ginderachter , Tony Lahoutte , Vicky Caveliers , Marleen Keyaerts

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent.

Cancers

Avec: Katrijn Broos , Quentin Lecocq , Catarina Xavier , Jessica Bridoux , Tham T Nguyen , Jurgen Corthals , Steve Schoonooghe , Eva Lion , Geert Raes , Marleen Keyaerts , Nick Devoogdt , Karine Breckpot

Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer.

EJNMMI research

Avec: Q Lecocq , P Debie , J Puttemans , R M Awad , L De Beck , T Ertveldt , Y De Vlaeminck , C Goyvaerts , G Raes , M Keyaerts , K Breckpot , N Devoogdt

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy.

Frontiers in immunology

Avec: Kirsten De Ridder , Hanne Locy , Elisa Piccioni , Miren Ibarra Zuazo , Robin Maximilian Awad , Stefaan Verhulst , Mathias Van Bulck , Yannick De Vlaeminck , Quentin Lecocq , Eva Reijmen , Wout De Mey , Lien De Beck , Thomas Ertveldt , Isabel Pintelon , Jean-Pierre Timmermans , David Escors , Marleen Keyaerts , Karine Breckpot , Cleo Goyvaerts

Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177-Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model.

Molecular cancer therapeutics

Avec: Thomas Ertveldt , Lien De Beck , Kirsten De Ridder , Hanne Locy , Wout de Mey , Cleo Goyvaerts , Quentin Lecocq , Hannelore Ceuppens , Yannick De Vlaeminck , Robin Maximilian Awad , Marleen Keyaerts , Nick Devoogdt , Matthias D'Huyvetter , Karine Breckpot , Ahmet Krasniqi

Emerging applications of nanobodies in cancer therapy.

International review of cell and molecular biology

Avec: Robin Maximilian Awad , Fien Meeus , Hannelore Ceuppens , Thomas Ertveldt , Heleen Hanssens , Quentin Lecocq , Lukasz Mateusiak , Katty Zeven , Hana Valenta , Timo W M De Groof , Yannick De Vlaeminck , Ahmet Krasniqi , Kim De Veirman , Cleo Goyvaerts , Matthias D'Huyvetter , Sophie Hernot , Nick Devoogdt , Karine Breckpot

Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization.

Frontiers in immunology

Avec: Heleen Hanssens , Fien Meeus , Yannick De Vlaeminck , Quentin Lecocq , Janik Puttemans , Pieterjan Debie , Timo W M De Groof , Cleo Goyvaerts , Kim De Veirman , Karine Breckpot , Nick Devoogdt

The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time's a Charm.

International journal of molecular sciences

Avec: Quentin Lecocq , Marleen Keyaerts , Nick Devoogdt , Karine Breckpot

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development.

Cancers

Avec: Yannick De De Vlaeminck , Stefano Bonelli , Robin Maximilian Awad , Maarten Dewilde , Sabrina Rizzolio , Quentin Lecocq , Evangelia Bolli , Ana Rita Santos , Damya Laoui , Steve Schoonooghe , Luca Tamagnone , Cleo Goyvaerts , Massimiliano Mazzone , Karine Breckpot , Jo A Van Ginderachter

Theranostics in immuno-oncology using nanobody derivatives.

Theranostics

Avec: Quentin Lecocq , Yannick De Vlaeminck , Heleen Hanssens , Matthias D'Huyvetter , Geert Raes , Cleo Goyvaerts , Marleen Keyaerts , Nick Devoogdt , Karine Breckpot

Therapeutic Efficacy of

Molecular pharmaceutics

Avec: Yana Dekempeneer , Vicky Caveliers , Maarten Ooms , Dominic Maertens , Mireille Gysemans , Tony Lahoutte , Catarina Xavier , Quentin Lecocq , Ken Maes , Peter Covens , Brian W Miller , Frank Bruchertseifer , Alfred Morgenstern , Thomas Cardinaels , Matthias D'Huyvetter

Preclinical Targeted α- and β

Cancers

Avec: Janik Puttemans , Yana Dekempeneer , Jos L Eersels , Heleen Hanssens , Pieterjan Debie , Marleen Keyaerts , Albert D Windhorst , Frank van der Aa , Quentin Lecocq , Karine Breckpot , Alfred Morgenstern , Frank Bruchertseifer , Tony Lahoutte , Nick Devoogdt , Matthias D'Huyvetter

Réseau de co-auteurs

Karine Breckpot 15 collaborations

Nick Devoogdt 12 collaborations

Marleen Keyaerts 11 collaborations

Cleo Goyvaerts 9 collaborations

Yannick De Vlaeminck 8 collaborations

Geert Raes 6 collaborations

Robin Maximilian Awad 6 collaborations

Matthias D'Huyvetter 5 collaborations

Thomas Ertveldt 4 collaborations

Catarina Xavier 4 collaborations

Heleen Hanssens 4 collaborations

Kris Thielemans 3 collaborations

Steve Schoonooghe 3 collaborations

Jo A Van Ginderachter 3 collaborations

Vicky Caveliers 3 collaborations

Tony Lahoutte 3 collaborations

Katrijn Broos 2 collaborations

Jurgen Corthals 2 collaborations

Eva Lion 2 collaborations

Katty Zeven 2 collaborations

Sam Massa 2 collaborations

Evangelia Bolli 2 collaborations

Wout de Mey 2 collaborations

Jessica Bridoux 2 collaborations

Kirsten De Ridder 2 collaborations

Hanne Locy 2 collaborations

Lien De Beck 2 collaborations

Hannelore Ceuppens 2 collaborations

Ahmet Krasniqi 2 collaborations

Fien Meeus 2 collaborations

Timo W M De Groof 2 collaborations

Kim De Veirman 2 collaborations

Janik Puttemans 2 collaborations

Pieterjan Debie 2 collaborations

Yana Dekempeneer 2 collaborations

Frank Bruchertseifer 2 collaborations

Alfred Morgenstern 2 collaborations

Brenda De Keersmaecker 1 collaboration

Sandrina Martens 1 collaboration

Philippe Giron 1 collaboration

Carlo Heirman 1 collaboration

Xenia Geeraerts 1 collaboration

Kiavash Movahedi 1 collaboration

Dora Mugoli Chigoho 1 collaboration

Odrade Gondry 1 collaboration

Laurens Raes 1 collaboration

Johannes Heemskerk 1 collaboration

Hendrik Everaert 1 collaboration

Lore Decoster 1 collaboration

Christel Fontaine 1 collaboration

Denis Schallier 1 collaboration

Sandrine Aspeslagh 1 collaboration

Ilse Vaneycken 1 collaboration

Tham T Nguyen 1 collaboration

Q Lecocq 1 collaboration

P Debie 1 collaboration

J Puttemans 1 collaboration

R M Awad 1 collaboration

L De Beck 1 collaboration

T Ertveldt 1 collaboration

Y De Vlaeminck 1 collaboration

C Goyvaerts 1 collaboration

G Raes 1 collaboration

M Keyaerts 1 collaboration

K Breckpot 1 collaboration

N Devoogdt 1 collaboration

Elisa Piccioni 1 collaboration

Miren Ibarra Zuazo 1 collaboration

Stefaan Verhulst 1 collaboration

Mathias Van Bulck 1 collaboration

Eva Reijmen 1 collaboration

Wout De Mey 1 collaboration

Isabel Pintelon 1 collaboration

Jean-Pierre Timmermans 1 collaboration

David Escors 1 collaboration

Lukasz Mateusiak 1 collaboration

Hana Valenta 1 collaboration

Sophie Hernot 1 collaboration

Yannick De De Vlaeminck 1 collaboration

Stefano Bonelli 1 collaboration

Maarten Dewilde 1 collaboration

Sabrina Rizzolio 1 collaboration

Ana Rita Santos 1 collaboration

Damya Laoui 1 collaboration

Luca Tamagnone 1 collaboration

Massimiliano Mazzone 1 collaboration

Maarten Ooms 1 collaboration

Dominic Maertens 1 collaboration

Mireille Gysemans 1 collaboration

Ken Maes 1 collaboration

Peter Covens 1 collaboration

Brian W Miller 1 collaboration

Thomas Cardinaels 1 collaboration

Jos L Eersels 1 collaboration

Albert D Windhorst 1 collaboration

Frank van der Aa 1 collaboration