Pierre Dubus

Affiliations

INSERM, Univ Bordeaux UMR1053 Bordeaux Research in Translational Oncology, F-33000, Bordeaux, France.
CHU de Bordeaux, F-33000, Bordeaux, France.

Publications (27)

Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts.

Scientific reports

Avec: Victoire Cardot-Ruffino , Véronique Chauvet , Cassandre Caligaris , Adrien Bertrand-Chapel , Nicolas Chuvin , Roxane M Pommier , Ulrich Valcourt , David F Vincent , Sylvie Martel , Sophie Aires , Bastien Kaniewski , Pierre Dubus , Philippe Cassier , Stéphanie Sentis , Laurent Bartholin

Loxl2 and Loxl3 Paralogues Play Redundant Roles during Mouse Development.

International journal of molecular sciences

Avec: Patricia G Santamaría , Pierre Dubus , José Bustos-Tauler , Alfredo Floristán , Alberto Vázquez-Naharro , Saleta Morales , Amparo Cano , Francisco Portillo

Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor.

Cell death discovery

Avec: Lornella Seeneevassen , Anissa Zaafour , Elodie Sifré , Coralie Genevois , Tra Ly Nguyen , Yasmine Pobiedonoscew , Alban Giese , Jérôme Guignard , Camille Tiffon , Benoit Rousseau , Anne-Aurélie Raymond , Geneviève Belleannée , Hélène Boeuf , Caroline Gronnier , Océane C B Martin , Julie Giraud , Philippe Lehours , Pierre Dubus , Christine Varon

Generation of induced pluripotent stem cells-derived hepatocyte-like cells for ex vivo gene therapy of primary hyperoxaluria type 1.

Stem cell research

Avec: Julie Estève , Jean-Marc Blouin , Magalie Lalanne , Lamia Azzi-Martin , Pierre Dubus , Audrey Bidet , Jérôme Harambat , Brigitte Llanas , Isabelle Moranvillier , Aurélie Bedel , François Moreau-Gaudry , Emmanuel Richard

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.

Cell death & disease

Avec: Anda Huna , Audrey Griveau , David Vindrieux , Sara Jaber , Jean-Michel Flaman , Delphine Goehrig , Lamia Azzi , Jean-Jacques Médard , Sophia Djebali , Hector Hernandez-Vargas , Robert Dante , Léa Payen , Jacqueline Marvel , Philippe Bertolino , Sébastien Aubert , Pierre Dubus , David Bernard

Hippo in Gastric Cancer: From Signalling to Therapy.

Cancers

Avec: Lornella Seeneevassen , Pierre Dubus , Caroline Gronnier , Christine Varon

CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Avec: Julie Giraud , Lornella Seeneevassen , Benoit Rousseau , Damien Bouriez , Elodie Sifré , Alban Giese , Tra Ly Nguyen , Camille Tiffon , Yannick Lippi , Lamia Azzi-Martin , Julie Pannequin , Armelle Ménard , Emilie Bessède , Cathy Staedel , Francis Mégraud , Geneviève Belleannée , Philippe Lehours , Caroline Gronnier , Pierre Dubus , Christine Varon

Inhibition of proprotein convertases activity results in repressed stemness and invasiveness of cancer stem cells in gastric cancer.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Avec: Anissa Zaafour , Lornella Seeneevassen , Tra Ly Nguyen , Coralie Genevois , Nour Nicolas , Elodie Sifré , Alban Giese , Chloé Porcheron , Jean Descarpentrie , Pierre Dubus , Abdel-Majid Khatib , Christine Varon

The "StemDif Sensor Test": A Straightforward, Non-Invasive Assay to Characterize the Secreted Stemness and/or Differentiation Activities of Tumor-Derived Cancer Cell Lines.

Biomedicines

Avec: Aya Abou Hammoud , Julie Giraud , Xavier Gauthereau , Camille Blanchard , Sophie Daburon , Marco Zese , Silvia Molina-Castro , Pierre Dubus , Christine Varon , Helene Boeuf

Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer.

Cancers

Avec: Lornella Seeneevassen , Julie Giraud , Silvia Molina-Castro , Elodie Sifré , Camille Tiffon , Clémentine Beauvoit , Cathy Staedel , Francis Mégraud , Philippe Lehours , Océane C B Martin , Hélène Boeuf , Pierre Dubus , Christine Varon

Alzheimer's Disease and Helicobacter pylori Infection: Inflammation from Stomach to Brain?

Journal of Alzheimer's disease : JAD

Avec: Guillaume Albaret , Elodie Sifré , Pauline Floch , Sophie Laye , Agnès Aubert , Pierre Dubus , Lamia Azzi-Martin , Alban Giese , Nathalie Salles , Francis Mégraud , Christine Varon , Philippe Lehours , Claire Roubaud-Baudron

APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infection.

Scientific reports

Avec: Alice Blosse , Sara Peru , Michael Levy , Benoit Marteyn , Pauline Floch , Elodie Sifré , Alban Giese , Martine Prochazkova-Carlotti , Lamia Azzi Martin , Pierre Dubus , Francis Mégraud , Agnès Ruskone Fournestraux , Bettina Fabiani , Christiane Copie Bergman , Cyrielle Robe , Michael Hahne , Bertrand Huard , Philippe Lehours

Generation of an Fsp1 (fibroblast-specific protein 1)-Flpo transgenic mouse strain.

Genesis (New York, N.Y. : 2000)

Avec: Victoire Cardot-Ruffino , Véronique Chauvet , Cassandre Caligaris , Adrien Bertrand-Chapel , Nicolas Chuvin , Roxane M Pommier , Ulrich Valcourt , David Vincent , Sylvie Martel , Sophie Aires , Bastien Kaniewski , Pierre Dubus , Philippe Cassier , Stéphanie Sentis , Laurent Bartholin

Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells.

PLoS pathogens

Avec: Lamia Azzi-Martin , Wencan He , Christelle Péré-Védrenne , Victoria Korolik , Chloé Alix , Martina Prochazkova-Carlotti , Jean-Luc Morel , Emilie Le Roux-Goglin , Philippe Lehours , Mojgan Djavaheri-Mergny , Christophe F Grosset , Christine Varon , Pierre Dubus , Armelle Ménard

The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1.

PLoS pathogens

Avec: Wencan He , Lamia Azzi-Martin , Valérie Velasco , Philippe Lehours , Pierre Dubus , Mojgan Djavaheri-Mergny , Armelle Ménard

E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer.

Cancer research

Avec: Celia López-Menéndez , Alberto Vázquez-Naharro , Vanesa Santos , Pierre Dubus , Patricia G Santamaría , Ángel Martínez-Ramírez , Francisco Portillo , Gema Moreno-Bueno , Marisa M Faraldo , Amparo Cano

Uncovering the Anticancer Potential of Murine Cytomegalovirus against Human Colon Cancer Cells.

Molecular therapy oncolytics

Avec: Layal Massara , Camille Khairallah , Nathalie Yared , Vincent Pitard , Benoit Rousseau , Julien Izotte , Alban Giese , Pierre Dubus , Xavier Gauthereau , Julie Déchanet-Merville , Myriam Capone

Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology.

Biochemical and biophysical research communications

Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination.

Cancers

Avec: Julie Giraud , Damien Bouriez , Lornella Seeneevassen , Benoit Rousseau , Elodie Sifré , Alban Giese , Francis Mégraud , Philippe Lehours , Pierre Dubus , Caroline Gronnier , Christine Varon

Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib

Haematologica

Avec: Pierre-Yves Dumas , Cécile Naudin , Séverine Martin-Lannerée , Brigitte Izac , Luana Casetti , Olivier Mansier , Benoît Rousseau , Alexandre Artus , Mélody Dufossée , Alban Giese , Pierre Dubus , Arnaud Pigneux , Vincent Praloran , Audrey Bidet , Arnaud Villacreces , Amélie Guitart , Noël Milpied , Olivier Kosmider , Isabelle Vigon , Vanessa Desplat , Isabelle Dusanter-Fourt , Jean-Max Pasquet

[Indolent T-lymphoblastic proliferation in association with localized Castleman disease: A case report].

Annales de pathologie

Avec: Bertrand Chauveau , François Le Loarer , Julia Bacci , François Baylac , Pierre Dubus , Catherine Ling , Marie Parrens

Gastric Cancer: Advances in Carcinogenesis Research and New Therapeutic Strategies.

International journal of molecular sciences

Avec: Lornella Seeneevassen , Emilie Bessède , Francis Mégraud , Philippe Lehours , Pierre Dubus , Christine Varon

The Hippo Kinase LATS2 Controls Helicobacter pylori-Induced Epithelial-Mesenchymal Transition and Intestinal Metaplasia in Gastric Mucosa.

Cellular and molecular gastroenterology and hepatology

Avec: Silvia Elena Molina-Castro , Camille Tiffon , Julie Giraud , Hélène Boeuf , Elodie Sifre , Alban Giese , Geneviève Belleannée , Philippe Lehours , Emilie Bessède , Francis Mégraud , Pierre Dubus , Cathy Staedel , Christine Varon

Verteporfin targeting YAP1/TAZ-TEAD transcriptional activity inhibits the tumorigenic properties of gastric cancer stem cells.

International journal of cancer

Avec: Julie Giraud , Silvia Molina-Castro , Lornella Seeneevassen , Elodie Sifré , Julien Izotte , Camille Tiffon , Cathy Staedel , Hélène Boeuf , Solène Fernandez , Philippe Barthelemy , Francis Megraud , Philippe Lehours , Pierre Dubus , Christine Varon

Reptin/RUVBL2 is required for hepatocyte proliferation in vivo, liver regeneration and homeostasis.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Joaquim Javary , Nathalie Allain , Zakaria Ezzoukhry , Sylvaine Di Tommaso , Jean-William Dupuy , Pierre Costet , Nathalie Dugot-Senant , Frédéric Saltel , Violaine Moreau , Pierre Dubus , Samira Benhamouche-Trouillet

Leukaemia inhibitory factor in gastric cancer: friend or foe?

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Avec: Lornella Seeneevassen , Océane C B Martin , Philippe Lehours , Pierre Dubus , Christine Varon

Cytolethal distending toxin modulates cell differentiation and elicits epithelial to mesenchymal transition.

The Journal of infectious diseases

Avec: Lamia Azzi-Martin , Valentin Touffait-Calvez , Maude Everaert , Ruxue Jia , Elodie Sifré , Lornella Seeneevassen , Christine Varon , Pierre Dubus , Armelle Ménard

Réseau de co-auteurs

Christine Varon 14 collaborations

Philippe Lehours 12 collaborations

Lornella Seeneevassen 10 collaborations

Elodie Sifré 9 collaborations

Alban Giese 9 collaborations

Julie Giraud 7 collaborations

Lamia Azzi-Martin 7 collaborations

Francis Mégraud 7 collaborations

Camille Tiffon 5 collaborations

Benoit Rousseau 4 collaborations

Hélène Boeuf 4 collaborations

Caroline Gronnier 4 collaborations

Armelle Ménard 4 collaborations

Cathy Staedel 4 collaborations

Tra Ly Nguyen 3 collaborations

Geneviève Belleannée 3 collaborations

Océane C B Martin 3 collaborations

Audrey Bidet 3 collaborations

Emilie Bessède 3 collaborations

Silvia Molina-Castro 3 collaborations

Victoire Cardot-Ruffino 2 collaborations

Véronique Chauvet 2 collaborations

Cassandre Caligaris 2 collaborations

Adrien Bertrand-Chapel 2 collaborations

Nicolas Chuvin 2 collaborations

Roxane M Pommier 2 collaborations

Ulrich Valcourt 2 collaborations

Sylvie Martel 2 collaborations

Sophie Aires 2 collaborations

Bastien Kaniewski 2 collaborations

Philippe Cassier 2 collaborations

Stéphanie Sentis 2 collaborations

Laurent Bartholin 2 collaborations

Patricia G Santamaría 2 collaborations

Alberto Vázquez-Naharro 2 collaborations

Amparo Cano 2 collaborations

Francisco Portillo 2 collaborations

Anissa Zaafour 2 collaborations

Coralie Genevois 2 collaborations

Julie Estève 2 collaborations

Jean-Marc Blouin 2 collaborations

Magalie Lalanne 2 collaborations

Jérôme Harambat 2 collaborations

Brigitte Llanas 2 collaborations

Isabelle Moranvillier 2 collaborations

Aurélie Bedel 2 collaborations

François Moreau-Gaudry 2 collaborations

Emmanuel Richard 2 collaborations

Damien Bouriez 2 collaborations

Xavier Gauthereau 2 collaborations

Pauline Floch 2 collaborations

Wencan He 2 collaborations

Mojgan Djavaheri-Mergny 2 collaborations

Julien Izotte 2 collaborations

David F Vincent 1 collaboration

José Bustos-Tauler 1 collaboration

Alfredo Floristán 1 collaboration

Saleta Morales 1 collaboration

Yasmine Pobiedonoscew 1 collaboration

Jérôme Guignard 1 collaboration

Anne-Aurélie Raymond 1 collaboration

Anda Huna 1 collaboration

Audrey Griveau 1 collaboration

David Vindrieux 1 collaboration

Sara Jaber 1 collaboration

Jean-Michel Flaman 1 collaboration

Delphine Goehrig 1 collaboration

Lamia Azzi 1 collaboration

Jean-Jacques Médard 1 collaboration

Sophia Djebali 1 collaboration

Hector Hernandez-Vargas 1 collaboration

Robert Dante 1 collaboration

Léa Payen 1 collaboration

Jacqueline Marvel 1 collaboration

Philippe Bertolino 1 collaboration

Sébastien Aubert 1 collaboration

David Bernard 1 collaboration

Yannick Lippi 1 collaboration

Julie Pannequin 1 collaboration

Nour Nicolas 1 collaboration

Chloé Porcheron 1 collaboration

Jean Descarpentrie 1 collaboration

Abdel-Majid Khatib 1 collaboration

Aya Abou Hammoud 1 collaboration

Camille Blanchard 1 collaboration

Sophie Daburon 1 collaboration

Marco Zese 1 collaboration

Helene Boeuf 1 collaboration

Clémentine Beauvoit 1 collaboration

Guillaume Albaret 1 collaboration

Sophie Laye 1 collaboration

Agnès Aubert 1 collaboration

Nathalie Salles 1 collaboration

Claire Roubaud-Baudron 1 collaboration

Alice Blosse 1 collaboration

Sara Peru 1 collaboration

Michael Levy 1 collaboration

Benoit Marteyn 1 collaboration

Martine Prochazkova-Carlotti 1 collaboration

Lamia Azzi Martin 1 collaboration

Agnès Ruskone Fournestraux 1 collaboration

Bettina Fabiani 1 collaboration

Christiane Copie Bergman 1 collaboration

Cyrielle Robe 1 collaboration

Michael Hahne 1 collaboration

Bertrand Huard 1 collaboration

David Vincent 1 collaboration

Christelle Péré-Védrenne 1 collaboration

Victoria Korolik 1 collaboration

Chloé Alix 1 collaboration

Martina Prochazkova-Carlotti 1 collaboration

Jean-Luc Morel 1 collaboration

Emilie Le Roux-Goglin 1 collaboration

Christophe F Grosset 1 collaboration

Valérie Velasco 1 collaboration

Celia López-Menéndez 1 collaboration

Vanesa Santos 1 collaboration

Ángel Martínez-Ramírez 1 collaboration

Gema Moreno-Bueno 1 collaboration

Marisa M Faraldo 1 collaboration

Layal Massara 1 collaboration

Camille Khairallah 1 collaboration

Nathalie Yared 1 collaboration

Vincent Pitard 1 collaboration

Julie Déchanet-Merville 1 collaboration

Myriam Capone 1 collaboration

Pierre-Yves Dumas 1 collaboration

Cécile Naudin 1 collaboration

Séverine Martin-Lannerée 1 collaboration

Brigitte Izac 1 collaboration

Luana Casetti 1 collaboration

Olivier Mansier 1 collaboration

Benoît Rousseau 1 collaboration

Alexandre Artus 1 collaboration

Mélody Dufossée 1 collaboration

Arnaud Pigneux 1 collaboration

Vincent Praloran 1 collaboration

Arnaud Villacreces 1 collaboration

Amélie Guitart 1 collaboration

Noël Milpied 1 collaboration

Olivier Kosmider 1 collaboration

Isabelle Vigon 1 collaboration

Vanessa Desplat 1 collaboration

Isabelle Dusanter-Fourt 1 collaboration

Jean-Max Pasquet 1 collaboration

Bertrand Chauveau 1 collaboration

François Le Loarer 1 collaboration

Julia Bacci 1 collaboration

François Baylac 1 collaboration

Catherine Ling 1 collaboration

Marie Parrens 1 collaboration

Silvia Elena Molina-Castro 1 collaboration

Elodie Sifre 1 collaboration

Solène Fernandez 1 collaboration

Philippe Barthelemy 1 collaboration

Francis Megraud 1 collaboration

Joaquim Javary 1 collaboration

Nathalie Allain 1 collaboration

Zakaria Ezzoukhry 1 collaboration

Sylvaine Di Tommaso 1 collaboration

Jean-William Dupuy 1 collaboration

Pierre Costet 1 collaboration

Nathalie Dugot-Senant 1 collaboration

Frédéric Saltel 1 collaboration

Violaine Moreau 1 collaboration

Samira Benhamouche-Trouillet 1 collaboration

Valentin Touffait-Calvez 1 collaboration

Maude Everaert 1 collaboration

Ruxue Jia 1 collaboration