Philippe Nghe

Affiliations

Laboratoire de Biochimie, UMR CNRS-ESPCI 8231 Chimie Biologie Innovation, PSL University, ESPCI Paris, 10 rue Vauquelin, 75005 Paris, France.

Publications (21)

Thresholds in Origin of Life Scenarios.

iScience

Avec: Cyrille Jeancolas , Christophe Malaterre , Philippe Nghe

Mineral surfaces select for longer RNA molecules.

Chemical communications (Cambridge, England)

Avec: Ryo Mizuuchi , Alex Blokhuis , Lena Vincent , Philippe Nghe , Niles Lehman , David Baum

Predicting Evolution Using Regulatory Architecture.

Annual review of biophysics

Avec: Philippe Nghe , Marjon G J de Vos , Enzo Kingma , Manjunatha Kogenaru , Frank J Poelwijk , Liedewij Laan , Sander J Tans

Large scale control and programming of gene expression using CRISPR.

Seminars in cell & developmental biology

Avec: Matthew Deyell , Sandeep Ameta , Philippe Nghe

Natural Selection beyond Life? A Workshop Report.

Life (Basel, Switzerland)

Avec: Sylvain Charlat , André Ariew , Pierrick Bourrat , María Ferreira Ruiz , Thomas Heams , Philippe Huneman , Sandeep Krishna , Michael Lachmann , Nicolas Lartillot , Louis Le Sergeant d'Hendecourt , Christophe Malaterre , Philippe Nghe , Etienne Rajon , Olivier Rivoire , Matteo Smerlak , Zorana Zeravcic

Abiogenesis through gradual evolution of autocatalysis into template-based replication.

FEBS letters

Avec: Polina Pavlinova , Camille N Lambert , Christophe Malaterre , Philippe Nghe

Small-molecule autocatalysis drives compartment growth, competition and reproduction.

Nature chemistry

Avec: Heng Lu , Alex Blokhuis , Rebecca Turk-MacLeod , Jayaprakash Karuppusamy , Andrea Franconi , Gabrielle Woronoff , Cyrille Jeancolas , Afshin Abrishamkar , Estelle Loire , Fabien Ferrage , Philippe Pelupessy , Ludovic Jullien , Eörs Szathmary , Philippe Nghe , Andrew D Griffiths

The generality of transient compartmentalization and its associated error thresholds.

Journal of theoretical biology

Avec: Alex Blokhuis , Philippe Nghe , Luca Peliti , David Lacoste

Recent insights into the genotype-phenotype relationship from massively parallel genetic assays.

Evolutionary applications

Avec: Harry Kemble , Philippe Nghe , Olivier Tenaillon

Darwinian properties and their trade-offs in autocatalytic RNA reaction networks.

Nature communications

Avec: Sandeep Ameta , Simon Arsène , Sophie Foulon , Baptiste Saudemont , Bryce E Clifton , Andrew D Griffiths , Philippe Nghe

RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling.

Chemical communications (Cambridge, England)

Avec: Cyrille Jeancolas , Yoshiya J Matsubara , Mykhailo Vybornyi , Camille N Lambert , Alex Blokhuis , Thomas Alline , Andrew D Griffiths , Sandeep Ameta , Sandeep Krishna , Philippe Nghe

Neonatal inflammation impairs developmentally-associated microglia and promotes a highly reactive microglial subset.

Brain, behavior, and immunity

Avec: Adrien Dufour , Ariane Heydari-Olya , Sophie Foulon , Clémence Réda , Amazigh Mokhtari , Valérie Faivre , Jennifer Hua , Cindy Bokobza , Andrew D Griffiths , Philippe Nghe , Pierre Gressens , Andrée Delahaye-Duriez , Juliette Van Steenwinckel

Metabolic cost of rapid adaptation of single yeast cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Gabrielle Woronoff , Philippe Nghe , Jean Baudry , Laurent Boitard , Erez Braun , Andrew D Griffiths , Jérôme Bibette

Predicting Evolutionary Constraints by Identifying Conflicting Demands in Regulatory Networks.

Cell systems

Avec: Manjunatha Kogenaru , Philippe Nghe , Frank J Poelwijk , Sander J Tans

Universal motifs and the diversity of autocatalytic systems.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Alex Blokhuis , David Lacoste , Philippe Nghe

The Origin of Life: What Is the Question?

Astrobiology

Avec: Christophe Malaterre , Cyrille Jeancolas , Philippe Nghe

An interdisciplinary effort to understand chemical organizations at the origin of life.

iScience

Avec: C Jeancolas , A Y Singh , S Jain , S Krishna , P Nghe

Towards parsimonious generative modeling of RNA families.

Nucleic acids research

Avec: Francesco Calvanese , Camille N Lambert , Philippe Nghe , Francesco Zamponi , Martin Weigt

Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway.

Science advances

Avec: Harry Kemble , Catherine Eisenhauer , Alejandro Couce , Audrey Chapron , Mélanie Magnan , Gregory Gautier , Hervé Le Nagard , Philippe Nghe , Olivier Tenaillon

Stoechiometric and dynamical autocatalysis for diluted chemical reaction networks.

Journal of mathematical biology

Avec: Jérémie Unterberger , Philippe Nghe

High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Kuang-Yu Chen , Jayaprakash Karuppusamy , Mary B O'Neill , Vaitea Opuu , Mathieu Bahin , Sophie Foulon , Pablo Ibanez , Lluis Quintana-Murci , Tatsuhiko Ozawa , Sylvie van der Werf , Philippe Nghe , Nadia Naffakh , Andrew Griffiths , Catherine Isel

Réseau de co-auteurs

Alex Blokhuis 5 collaborations

Andrew D Griffiths 5 collaborations

Cyrille Jeancolas 4 collaborations

Christophe Malaterre 4 collaborations

Sandeep Ameta 3 collaborations

Camille N Lambert 3 collaborations

Sophie Foulon 3 collaborations

Manjunatha Kogenaru 2 collaborations

Frank J Poelwijk 2 collaborations

Sander J Tans 2 collaborations

Sandeep Krishna 2 collaborations

Jayaprakash Karuppusamy 2 collaborations

Gabrielle Woronoff 2 collaborations

David Lacoste 2 collaborations

Harry Kemble 2 collaborations

Olivier Tenaillon 2 collaborations

Ryo Mizuuchi 1 collaboration

Lena Vincent 1 collaboration

Niles Lehman 1 collaboration

David Baum 1 collaboration

Marjon G J de Vos 1 collaboration

Enzo Kingma 1 collaboration

Liedewij Laan 1 collaboration

Matthew Deyell 1 collaboration

Sylvain Charlat 1 collaboration

André Ariew 1 collaboration

Pierrick Bourrat 1 collaboration

María Ferreira Ruiz 1 collaboration

Thomas Heams 1 collaboration

Philippe Huneman 1 collaboration

Michael Lachmann 1 collaboration

Nicolas Lartillot 1 collaboration

Louis Le Sergeant d'Hendecourt 1 collaboration

Etienne Rajon 1 collaboration

Olivier Rivoire 1 collaboration

Matteo Smerlak 1 collaboration

Zorana Zeravcic 1 collaboration

Polina Pavlinova 1 collaboration

Heng Lu 1 collaboration

Rebecca Turk-MacLeod 1 collaboration

Andrea Franconi 1 collaboration

Afshin Abrishamkar 1 collaboration

Estelle Loire 1 collaboration

Fabien Ferrage 1 collaboration

Philippe Pelupessy 1 collaboration

Ludovic Jullien 1 collaboration

Eörs Szathmary 1 collaboration

Luca Peliti 1 collaboration

Simon Arsène 1 collaboration

Baptiste Saudemont 1 collaboration

Bryce E Clifton 1 collaboration

Yoshiya J Matsubara 1 collaboration

Mykhailo Vybornyi 1 collaboration

Thomas Alline 1 collaboration

Adrien Dufour 1 collaboration

Ariane Heydari-Olya 1 collaboration

Clémence Réda 1 collaboration

Amazigh Mokhtari 1 collaboration

Valérie Faivre 1 collaboration

Jennifer Hua 1 collaboration

Cindy Bokobza 1 collaboration

Pierre Gressens 1 collaboration

Andrée Delahaye-Duriez 1 collaboration

Juliette Van Steenwinckel 1 collaboration

Jean Baudry 1 collaboration

Laurent Boitard 1 collaboration

Erez Braun 1 collaboration

Jérôme Bibette 1 collaboration

C Jeancolas 1 collaboration

A Y Singh 1 collaboration

S Jain 1 collaboration

S Krishna 1 collaboration

P Nghe 1 collaboration

Francesco Calvanese 1 collaboration

Francesco Zamponi 1 collaboration

Martin Weigt 1 collaboration

Catherine Eisenhauer 1 collaboration

Alejandro Couce 1 collaboration

Audrey Chapron 1 collaboration

Mélanie Magnan 1 collaboration

Gregory Gautier 1 collaboration

Hervé Le Nagard 1 collaboration

Jérémie Unterberger 1 collaboration

Kuang-Yu Chen 1 collaboration

Mary B O'Neill 1 collaboration

Vaitea Opuu 1 collaboration

Mathieu Bahin 1 collaboration

Pablo Ibanez 1 collaboration

Lluis Quintana-Murci 1 collaboration

Tatsuhiko Ozawa 1 collaboration

Sylvie van der Werf 1 collaboration

Nadia Naffakh 1 collaboration

Andrew Griffiths 1 collaboration

Catherine Isel 1 collaboration