Pegah Jafarinasabian

Affiliations

Amgen Inc., Thousand Oaks, CA, USA.

Publications (13)

Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations.

British journal of clinical pharmacology

Avec: Ashit Trivedi , Cheng-Pang Hsu , Pegah Jafarinasabian , Bianca Terminello , Hanze Zhang , Stephen Flach , Samuel Israel , Ashley Brooks , Hongqi Xue , Borje Darpo , Siddique Abbasi , Sandeep Dutta , Edward Lee

Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval.

Journal of bone oncology

Avec: Benoit Cadieux , Robert Coleman , Pegah Jafarinasabian , Allan Lipton , Robert Z Orlowski , Fred Saad , Giorgio V Scagliotti , Kazuyuki Shimizu , Alison Stopeck

Effect of Varying Degrees of Renal Impairment on the Pharmacokinetics of Omecamtiv Mecarbil.

Clinical pharmacokinetics

Avec: Ashit Trivedi , Rajneet K Oberoi , Pegah Jafarinasabian , Hanze Zhang , Stephen Flach , Siddique Abbasi , Sandeep Dutta , Edward Lee

Pharmacokinetic Drug-Drug Interaction Study of Omecamtiv Mecarbil With Omeprazole, a Proton Pump Inhibitor, in Healthy Subjects.

Clinical pharmacology in drug development

Avec: Ashit Trivedi , Winnie Sohn , Pegah Jafarinasabian , Hanze Zhang , Bianca Terminello , Stephen Flach , Siddique Abbasi , Sandeep Dutta , Edward Lee

A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma.

Investigational new drugs

Avec: David C Smith , Matthias Kroiss , Electron Kebebew , Mouhammed Amir Habra , Rashmi Chugh , Bryan J Schneider , Martin Fassnacht , Pegah Jafarinasabian , M Marian Ijzerman , Vivian H Lin , Pharis Mohideen , Aung Naing

Evaluation of drug-drug interaction potential between omecamtiv mecarbil and rosuvastatin, a BCRP substrate, with a clinical study in healthy subjects and using a physiologically-based pharmacokinetic model.

Clinical and translational science

Avec: Ashit Trivedi , Winnie Sohn , Priyanka Kulkarni , Pegah Jafarinasabian , Hanze Zhang , Marintan Spring , Stephen Flach , Siddique Abbasi , Jan Wahlstrom , Edward Lee , Sandeep Dutta

Relative Bioavailability of Omecamtiv Mecarbil Pediatric Minitablet Formulations in Healthy Adult Subjects.

Clinical drug investigation

Avec: Ashit Trivedi , Mia Mackowski , Pegah Jafarinasabian , Hanze Zhang , Stephen Flach , Bianca Terminello , Ajay Bhatia , Sandeep Dutta , Edward Lee

Pharmacokinetic Evaluation of the CYP3A4 and CYP2D6 Drug-Drug Interaction and CYP3A4 Induction Potential of Omecamtiv Mecarbil: Two Open-Label Studies in Healthy Subjects.

Clinical pharmacology in drug development

Avec: Ashit Trivedi , Fady I Malik , Pegah Jafarinasabian , Hanze Zhang , Stephen Flach , Siddique Abbasi , Sandeep Dutta , Edward Lee

Pharmacokinetic Drug-Drug Interaction Study of Omecamtiv Mecarbil With Amiodarone and Digoxin in Healthy Subjects.

Clinical pharmacology in drug development

Avec: Ashit Trivedi , Winnie Sohn , Cheng-Pang Hsu , Pegah Jafarinasabian , Hanze Zhang , Shauna Hutton , Stephen Flach , Siddique Abbasi , Sandeep Dutta , Edward Lee

Effect of Omecamtiv Mecarbil on the Pharmacokinetics of Metformin, a Probe Substrate for MATE1/MATE2-K, in Healthy Subjects.

Clinical drug investigation

Avec: Ashit Trivedi , Rajneet K Oberoi , Pegah Jafarinasabian , Hanze Zhang , Marintan Spring , Stephen Flach , Siddique Abbasi , Sandeep Dutta , Edward Lee

Switchability and minimal effect of food on pharmacokinetics of modified release tablet strengths of omecamtiv mecarbil, a cardiac myosin activator.

Biopharmaceutics & drug disposition

Avec: Ashit Trivedi , Rajneet K Oberoi , Mia Mackowski , Pegah Jafarinasabian , Hanze Zhang , Stephen Flach , Mary Ann Simiens , Bianca Terminello , Siddique Abbasi , Sandeep Dutta , Edward Lee

Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil.

Clinical pharmacology in drug development

Avec: Ashit Trivedi , Rajneet K Oberoi , Mia Mackowski , Pegah Jafarinasabian , Hanze Zhang , Stephen Flach , Shauna Hutton , Siddique Abbasi , Sandeep Dutta , Edward Lee

Sotorasib in

The New England journal of medicine

Avec: John H Strickler , Hironaga Satake , Thomas J George , Rona Yaeger , Antoine Hollebecque , Ignacio Garrido-Laguna , Martin Schuler , Timothy F Burns , Andrew L Coveler , Gerald S Falchook , Mark Vincent , Yu Sunakawa , Laetitia Dahan , David Bajor , Sun-Young Rha , Charlotte Lemech , Dejan Juric , Marko Rehn , Gataree Ngarmchamnanrith , Pegah Jafarinasabian , Qui Tran , David S Hong

Réseau de co-auteurs

Ashit Trivedi 10 collaborations

Hanze Zhang 10 collaborations

Stephen Flach 10 collaborations

Sandeep Dutta 10 collaborations

Edward Lee 10 collaborations

Siddique Abbasi 9 collaborations

Bianca Terminello 4 collaborations

Rajneet K Oberoi 4 collaborations

Winnie Sohn 3 collaborations

Mia Mackowski 3 collaborations

Cheng-Pang Hsu 2 collaborations

Marintan Spring 2 collaborations

Shauna Hutton 2 collaborations

Samuel Israel 1 collaboration

Ashley Brooks 1 collaboration

Hongqi Xue 1 collaboration

Borje Darpo 1 collaboration

Benoit Cadieux 1 collaboration

Robert Coleman 1 collaboration

Allan Lipton 1 collaboration

Robert Z Orlowski 1 collaboration

Fred Saad 1 collaboration

Giorgio V Scagliotti 1 collaboration

Kazuyuki Shimizu 1 collaboration

Alison Stopeck 1 collaboration

David C Smith 1 collaboration

Matthias Kroiss 1 collaboration

Electron Kebebew 1 collaboration

Mouhammed Amir Habra 1 collaboration

Rashmi Chugh 1 collaboration

Bryan J Schneider 1 collaboration

Martin Fassnacht 1 collaboration

M Marian Ijzerman 1 collaboration

Vivian H Lin 1 collaboration

Pharis Mohideen 1 collaboration

Aung Naing 1 collaboration

Priyanka Kulkarni 1 collaboration

Jan Wahlstrom 1 collaboration

Ajay Bhatia 1 collaboration

Fady I Malik 1 collaboration

Mary Ann Simiens 1 collaboration

John H Strickler 1 collaboration

Hironaga Satake 1 collaboration

Thomas J George 1 collaboration

Rona Yaeger 1 collaboration

Antoine Hollebecque 1 collaboration

Ignacio Garrido-Laguna 1 collaboration

Martin Schuler 1 collaboration

Timothy F Burns 1 collaboration

Andrew L Coveler 1 collaboration

Gerald S Falchook 1 collaboration

Mark Vincent 1 collaboration

Yu Sunakawa 1 collaboration

Laetitia Dahan 1 collaboration

David Bajor 1 collaboration

Sun-Young Rha 1 collaboration

Charlotte Lemech 1 collaboration

Dejan Juric 1 collaboration

Marko Rehn 1 collaboration

Gataree Ngarmchamnanrith 1 collaboration

Qui Tran 1 collaboration

David S Hong 1 collaboration