Osama Al-Dalahmah

Affiliations

Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center and the New York Presbyterian Hospital, New York, NY, USA. oa2298@cumc.columbia.edu.

Publications (22)

Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage.

Acta neuropathologica communications

Avec: Osama Al-Dalahmah , Kiran T Thakur , Anna S Nordvig , Morgan L Prust , William Roth , Angela Lignelli , Anne-Catrin Uhlemann , Emily Happy Miller , Shajo Kunnath-Velayudhan , Armando Del Portillo , Yang Liu , Gunnar Hargus , Andrew F Teich , Richard A Hickman , Kurenai Tanji , James E Goldman , Phyllis L Faust , Peter Canoll

A 53-year-old woman with a rapidly progressive, non-enhancing left frontotemporal lesion.

Brain pathology (Zurich, Switzerland)

Avec: Michael L Miller , Daniel W Griepp , Yu Sun , Sean Tamir , Rebecca Straus Farber , Marc L Otten , Osama Al-Dalahmah

The link between SARS-CoV-2 related microglial reactivity and astrocyte pathology in the inferior olivary nucleus.

Frontiers in neuroscience

Avec: Nacoya Madden , Ying Zi Jessy Mei , Kelly Jakubiak , Juncheng Li , Gunnar Hargus , James E Goldman , Osama Al-Dalahmah

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside.

NPJ Parkinson's disease

Avec: David Sulzer , Angelo Antonini , Valentina Leta , Anna Nordvig , Richard J Smeyne , James E Goldman , Osama Al-Dalahmah , Luigi Zecca , Alessandro Sette , Luigi Bubacco , Olimpia Meucci , Elena Moro , Ashley S Harms , Yaqian Xu , Stanley Fahn , K Ray Chaudhuri

Galectin-3 diminishes Wnt signaling in the postnatal subventricular zone.

Stem cells (Dayton, Ohio)

Avec: Osama Al-Dalahmah , James Nicholson , Swip Draijer , Luana Campos Soares , Francis G Szele

The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina.

Cell reports

Avec: Mathilde Pruvost , Julia Patzig , Camila Yattah , Ipek Selcen , Marylens Hernandez , Hye-Jin Park , Sarah Moyon , Shibo Liu , Malia S Morioka , Lindsay Shopland , Osama Al-Dalahmah , Jaroslav Bendl , John F Fullard , Panos Roussos , James Goldman , Ye He , Jeffrey L Dupree , Patrizia Casaccia

Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APP

Acta neuropathologica

Avec: Wenhui Qu , Matti Lam , Julie J McInvale , Jason A Mares , Sam Kwon , Nelson Humala , Aayushi Mahajan , Trang Nguyen , Kelly A Jakubiak , Jeong-Yeon Mun , Thomas G Tedesco , Osama Al-Dalahmah , Syed A Hussaini , Andrew A Sproul , Markus D Siegelin , Philip L De Jager , Peter Canoll , Vilas Menon , Gunnar Hargus

Galectin-3 modulates postnatal subventricular zone gliogenesis.

Glia

Avec: Osama Al-Dalahmah , Luana Campos Soares , James Nicholson , Swip Draijer , Mayara Mundim , Victor M Lu , Bin Sun , Teadora Tyler , István Adorján , Eric O'Neill , Francis G Szele

Spatially resolved isotope tracing reveals tissue metabolic activity.

Nature methods

Avec: Lin Wang , Xi Xing , Xianfeng Zeng , S RaElle Jackson , Tara TeSlaa , Osama Al-Dalahmah , Laith Z Samarah , Katharine Goodwin , Lifeng Yang , Melanie R McReynolds , Xiaoxuan Li , Jeremy J Wolff , Joshua D Rabinowitz , Shawn M Davidson

Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state.

bioRxiv : the preprint server for biology

Avec: Fahad Paryani , Ji-Sun Kwon , Chris W Ng , Nacoya Madden , Kenneth Ofori , Alice Tang , Hong Lu , Juncheng Li , Aayushi Mahajan , Shawn M Davidson , Anna Basile , Caitlin McHugh , Jean Paul Vonsattel , Richard Hickman , Michael Zody , David E Houseman , James E Goldman , Andrew S Yoo , Vilas Menon , Osama Al-Dalahmah

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

Cell reports

Avec: Xiaoping Wu , Alexander A Sosunov , Wudu Lado , Jia Jie Teoh , Ahrom Ham , Hongyu Li , Osama Al-Dalahmah , Brian J A Gill , Ottavio Arancio , Catherine A Schevon , Wayne N Frankel , Guy M McKhann , David Sulzer , James E Goldman , Guomei Tang

Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial.

The Lancet. Oncology

Avec: Eleonora F Spinazzi , Michael G Argenziano , Pavan S Upadhyayula , Matei A Banu , Justin A Neira , Dominique M O Higgins , Peter B Wu , Brianna Pereira , Aayushi Mahajan , Nelson Humala , Osama Al-Dalahmah , Wenting Zhao , Akshay V Save , Brian J A Gill , Deborah M Boyett , Tamara Marie , Julia L Furnari , Tejaswi D Sudhakar , Sylwia A Stopka , Michael S Regan , Vanessa Catania , Laura Good , Stergios Zacharoulis , Meenu Behl , Petros Petridis , Sachin Jambawalikar , Akiva Mintz , Angela Lignelli , Nathalie Y R Agar , Peter A Sims , Mary R Welch , Andrew B Lassman , Fabio M Iwamoto , Randy S D'Amico , Jack Grinband , Peter Canoll , Jeffrey N Bruce

Single-nucleus RNA-seq identifies Huntington disease astrocyte states.

Acta neuropathologica communications

Avec: Osama Al-Dalahmah , Alexander A Sosunov , A Shaik , Kenneth Ofori , Yang Liu , Jean Paul Vonsattel , Istvan Adorjan , Vilas Menon , James E Goldman

Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases.

Cells

Avec: Luana C Soares , Osama Al-Dalahmah , James Hillis , Christopher C Young , Isaiah Asbed , Masanori Sakaguchi , Eric O'Neill , Francis G Szele

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states.

Nature communications

Avec: Osama Al-Dalahmah , Michael G Argenziano , Adithya Kannan , Aayushi Mahajan , Julia Furnari , Fahad Paryani , Deborah Boyett , Akshay Save , Nelson Humala , Fatima Khan , Juncheng Li , Hong Lu , Yu Sun , John F Tuddenham , Alexander R Goldberg , Athanassios Dovas , Matei A Banu , Tejaswi Sudhakar , Erin Bush , Andrew B Lassman , Guy M McKhann , Brian J A Gill , Brett Youngerman , Michael B Sisti , Jeffrey N Bruce , Peter A Sims , Vilas Menon , Peter Canoll

Biologically-informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post-treatment glioblastoma.

Research square

Avec: Jing Li , Hairong Wang , Michael Argenziano , Hyunsoo Yoon , Deborah Boyett , Akshay Save , Petros Petridis , William Savage , Pamela Jackson , Andrea Hawkins-Daarud , Nhan Tran , Leland Hu , Osama Al-Dalahmah , Jeffrey Bruce , Jack Grinband , Kristin Swanson , Peter Canoll

Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state.

Nature communications

Avec: Fahad Paryani , Ji-Sun Kwon , Christopher W Ng , Kelly Jakubiak , Nacoya Madden , Kenneth Ofori , Alice Tang , Hong Lu , Shengnan Xia , Juncheng Li , Aayushi Mahajan , Shawn M Davidson , Anna O Basile , Caitlin McHugh , Jean Paul Vonsattel , Richard Hickman , Michael C Zody , David E Housman , James E Goldman , Andrew S Yoo , Vilas Menon , Osama Al-Dalahmah

Epithelial sheath neuroma: A case report and literature review.

Clinical neuropathology

Avec: Osama Al-Dalahmah , Caleb McEntire , George W Niedt

COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital.

Brain : a journal of neurology

Avec: Kiran T Thakur , Emily Happy Miller , Michael D Glendinning , Osama Al-Dalahmah , Matei A Banu , Amelia K Boehme , Alexandra L Boubour , Samuel S Bruce , Alexander M Chong , Jan Claassen , Phyllis L Faust , Gunnar Hargus , Richard A Hickman , Sachin Jambawalikar , Alexander G Khandji , Carla Y Kim , Robyn S Klein , Angela Lignelli-Dipple , Chun-Chieh Lin , Yang Liu , Michael L Miller , Gul Moonis , Anna S Nordvig , Jonathan B Overdevest , Morgan L Prust , Serge Przedborski , William H Roth , Allison Soung , Kurenai Tanji , Andrew F Teich , Dritan Agalliu , Anne-Catrin Uhlemann , James E Goldman , Peter Canoll

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.

Nature communications

Avec: Ryan G Lim , Osama Al-Dalahmah , Jie Wu , Maxwell P Gold , Jack C Reidling , Guomei Tang , Miriam Adam , David K Dansu , Hye-Jin Park , Patrizia Casaccia , Ricardo Miramontes , Andrea M Reyes-Ortiz , Alice Lau , Richard A Hickman , Fatima Khan , Fahad Paryani , Alice Tang , Kenneth Ofori , Emily Miyoshi , Neethu Michael , Nicolette McClure , Xena E Flowers , Jean Paul Vonsattel , Shawn Davidson , Vilas Menon , Vivek Swarup , Ernest Fraenkel , James E Goldman , Leslie M Thompson

The Matrix Receptor CD44 Is Present in Astrocytes throughout the Human Central Nervous System and Accumulates in Hypoxia and Seizures.

Cells

Avec: Osama Al-Dalahmah , Alexander A Sosunov , Yu Sun , Yang Liu , Nacoya Madden , E Sander Connolly , Carol M Troy , Guy M McKhann , James E Goldman

Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.

Cell stem cell

Avec: Osama Al-Dalahmah , Matti Lam , Julie J McInvale , Wenhui Qu , Trang Nguyen , Jeong-Yeon Mun , Sam Kwon , Nkechime Ifediora , Aayushi Mahajan , Nelson Humala , Tristan Winters , Ellen Angeles , Kelly A Jakubiak , Rebekka Kühn , Yoon A Kim , Maria Caterina De Rosa , Claudia A Doege , Fahad Paryani , Xena Flowers , Athanassios Dovas , Angeliki Mela , Hong Lu , Michael A DeTure , Jean Paul Vonsattel , Zbigniew K Wszolek , Dennis W Dickson , Tanja Kuhlmann , Holm Zaehres , Hans R Schöler , Andrew A Sproul , Markus D Siegelin , Philip L De Jager , James E Goldman , Vilas Menon , Peter Canoll , Gunnar Hargus

Réseau de co-auteurs

James E Goldman 11 collaborations

Peter Canoll 7 collaborations

Vilas Menon 7 collaborations

Aayushi Mahajan 6 collaborations

Gunnar Hargus 5 collaborations

Fahad Paryani 5 collaborations

Jean Paul Vonsattel 5 collaborations

Yang Liu 4 collaborations

Nacoya Madden 4 collaborations

Juncheng Li 4 collaborations

Nelson Humala 4 collaborations

Kenneth Ofori 4 collaborations

Hong Lu 4 collaborations

Richard A Hickman 3 collaborations

Yu Sun 3 collaborations

Francis G Szele 3 collaborations

Shawn M Davidson 3 collaborations

Alice Tang 3 collaborations

Alexander A Sosunov 3 collaborations

Brian J A Gill 3 collaborations

Guy M McKhann 3 collaborations

Matei A Banu 3 collaborations

Kiran T Thakur 2 collaborations

Anna S Nordvig 2 collaborations

Morgan L Prust 2 collaborations

Angela Lignelli 2 collaborations

Anne-Catrin Uhlemann 2 collaborations

Emily Happy Miller 2 collaborations

Andrew F Teich 2 collaborations

Kurenai Tanji 2 collaborations

Phyllis L Faust 2 collaborations

Michael L Miller 2 collaborations

Kelly Jakubiak 2 collaborations

David Sulzer 2 collaborations

James Nicholson 2 collaborations

Swip Draijer 2 collaborations

Luana Campos Soares 2 collaborations

Hye-Jin Park 2 collaborations

Patrizia Casaccia 2 collaborations

Wenhui Qu 2 collaborations

Matti Lam 2 collaborations

Julie J McInvale 2 collaborations

Sam Kwon 2 collaborations

Trang Nguyen 2 collaborations

Kelly A Jakubiak 2 collaborations

Jeong-Yeon Mun 2 collaborations

Andrew A Sproul 2 collaborations

Markus D Siegelin 2 collaborations

Philip L De Jager 2 collaborations

Eric O'Neill 2 collaborations

Ji-Sun Kwon 2 collaborations

Caitlin McHugh 2 collaborations

Richard Hickman 2 collaborations

Andrew S Yoo 2 collaborations

Guomei Tang 2 collaborations

Michael G Argenziano 2 collaborations

Petros Petridis 2 collaborations

Sachin Jambawalikar 2 collaborations

Peter A Sims 2 collaborations

Andrew B Lassman 2 collaborations

Jack Grinband 2 collaborations

Jeffrey N Bruce 2 collaborations

Deborah Boyett 2 collaborations

Akshay Save 2 collaborations

Fatima Khan 2 collaborations

Athanassios Dovas 2 collaborations

William Roth 1 collaboration

Shajo Kunnath-Velayudhan 1 collaboration

Armando Del Portillo 1 collaboration

Daniel W Griepp 1 collaboration

Sean Tamir 1 collaboration

Rebecca Straus Farber 1 collaboration

Marc L Otten 1 collaboration

Ying Zi Jessy Mei 1 collaboration

Angelo Antonini 1 collaboration

Valentina Leta 1 collaboration

Anna Nordvig 1 collaboration

Richard J Smeyne 1 collaboration

Luigi Zecca 1 collaboration

Alessandro Sette 1 collaboration

Luigi Bubacco 1 collaboration

Olimpia Meucci 1 collaboration

Elena Moro 1 collaboration

Ashley S Harms 1 collaboration

Yaqian Xu 1 collaboration

Stanley Fahn 1 collaboration

K Ray Chaudhuri 1 collaboration

Mathilde Pruvost 1 collaboration

Julia Patzig 1 collaboration

Camila Yattah 1 collaboration

Ipek Selcen 1 collaboration

Marylens Hernandez 1 collaboration

Sarah Moyon 1 collaboration

Shibo Liu 1 collaboration

Malia S Morioka 1 collaboration

Lindsay Shopland 1 collaboration

Jaroslav Bendl 1 collaboration

John F Fullard 1 collaboration

Panos Roussos 1 collaboration

James Goldman 1 collaboration

Ye He 1 collaboration

Jeffrey L Dupree 1 collaboration

Jason A Mares 1 collaboration

Thomas G Tedesco 1 collaboration

Syed A Hussaini 1 collaboration

Mayara Mundim 1 collaboration

Victor M Lu 1 collaboration

Bin Sun 1 collaboration

Teadora Tyler 1 collaboration

István Adorján 1 collaboration

Lin Wang 1 collaboration

Xi Xing 1 collaboration

Xianfeng Zeng 1 collaboration

S RaElle Jackson 1 collaboration

Tara TeSlaa 1 collaboration

Laith Z Samarah 1 collaboration

Katharine Goodwin 1 collaboration

Lifeng Yang 1 collaboration

Melanie R McReynolds 1 collaboration

Xiaoxuan Li 1 collaboration

Jeremy J Wolff 1 collaboration

Joshua D Rabinowitz 1 collaboration

Chris W Ng 1 collaboration

Anna Basile 1 collaboration

Michael Zody 1 collaboration

David E Houseman 1 collaboration

Xiaoping Wu 1 collaboration

Wudu Lado 1 collaboration

Jia Jie Teoh 1 collaboration

Ahrom Ham 1 collaboration

Hongyu Li 1 collaboration

Ottavio Arancio 1 collaboration

Catherine A Schevon 1 collaboration

Wayne N Frankel 1 collaboration

Eleonora F Spinazzi 1 collaboration

Pavan S Upadhyayula 1 collaboration

Justin A Neira 1 collaboration

Dominique M O Higgins 1 collaboration

Peter B Wu 1 collaboration

Brianna Pereira 1 collaboration

Wenting Zhao 1 collaboration

Akshay V Save 1 collaboration

Deborah M Boyett 1 collaboration

Tamara Marie 1 collaboration

Julia L Furnari 1 collaboration

Tejaswi D Sudhakar 1 collaboration

Sylwia A Stopka 1 collaboration

Michael S Regan 1 collaboration

Vanessa Catania 1 collaboration

Laura Good 1 collaboration

Stergios Zacharoulis 1 collaboration

Meenu Behl 1 collaboration

Akiva Mintz 1 collaboration

Nathalie Y R Agar 1 collaboration

Mary R Welch 1 collaboration

Fabio M Iwamoto 1 collaboration

Randy S D'Amico 1 collaboration

A Shaik 1 collaboration

Istvan Adorjan 1 collaboration

Luana C Soares 1 collaboration

James Hillis 1 collaboration

Christopher C Young 1 collaboration

Isaiah Asbed 1 collaboration

Masanori Sakaguchi 1 collaboration

Adithya Kannan 1 collaboration

Julia Furnari 1 collaboration

John F Tuddenham 1 collaboration

Alexander R Goldberg 1 collaboration

Tejaswi Sudhakar 1 collaboration

Erin Bush 1 collaboration

Brett Youngerman 1 collaboration

Michael B Sisti 1 collaboration

Jing Li 1 collaboration

Hairong Wang 1 collaboration

Michael Argenziano 1 collaboration

Hyunsoo Yoon 1 collaboration

William Savage 1 collaboration

Pamela Jackson 1 collaboration

Andrea Hawkins-Daarud 1 collaboration

Nhan Tran 1 collaboration

Leland Hu 1 collaboration

Jeffrey Bruce 1 collaboration

Kristin Swanson 1 collaboration

Christopher W Ng 1 collaboration

Shengnan Xia 1 collaboration

Anna O Basile 1 collaboration

Michael C Zody 1 collaboration

David E Housman 1 collaboration

Caleb McEntire 1 collaboration

George W Niedt 1 collaboration

Michael D Glendinning 1 collaboration

Amelia K Boehme 1 collaboration

Alexandra L Boubour 1 collaboration

Samuel S Bruce 1 collaboration

Alexander M Chong 1 collaboration

Jan Claassen 1 collaboration

Alexander G Khandji 1 collaboration

Carla Y Kim 1 collaboration

Robyn S Klein 1 collaboration

Angela Lignelli-Dipple 1 collaboration

Chun-Chieh Lin 1 collaboration

Gul Moonis 1 collaboration

Jonathan B Overdevest 1 collaboration

Serge Przedborski 1 collaboration

William H Roth 1 collaboration

Allison Soung 1 collaboration

Dritan Agalliu 1 collaboration

Ryan G Lim 1 collaboration

Jie Wu 1 collaboration

Maxwell P Gold 1 collaboration

Jack C Reidling 1 collaboration

Miriam Adam 1 collaboration

David K Dansu 1 collaboration

Ricardo Miramontes 1 collaboration

Andrea M Reyes-Ortiz 1 collaboration

Alice Lau 1 collaboration

Emily Miyoshi 1 collaboration

Neethu Michael 1 collaboration

Nicolette McClure 1 collaboration

Xena E Flowers 1 collaboration

Shawn Davidson 1 collaboration

Vivek Swarup 1 collaboration

Ernest Fraenkel 1 collaboration

Leslie M Thompson 1 collaboration

E Sander Connolly 1 collaboration

Carol M Troy 1 collaboration

Nkechime Ifediora 1 collaboration

Tristan Winters 1 collaboration

Ellen Angeles 1 collaboration

Rebekka Kühn 1 collaboration

Yoon A Kim 1 collaboration

Maria Caterina De Rosa 1 collaboration

Claudia A Doege 1 collaboration

Xena Flowers 1 collaboration

Angeliki Mela 1 collaboration

Michael A DeTure 1 collaboration

Zbigniew K Wszolek 1 collaboration

Dennis W Dickson 1 collaboration

Tanja Kuhlmann 1 collaboration

Holm Zaehres 1 collaboration

Hans R Schöler 1 collaboration