Orian Shirihai

Affiliations

Division of Endocrinology, Department of Medicine, and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.

Publications (13)

Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet-Induced Insulin Resistance in Mice.

Molecular nutrition & food research

Avec: Jieping Yang , Yuanqiang Guo , Susanne M Henning , Brenda Chan , Jianfeng Long , Jin Zhong , Rebeca Acin-Perez , Anton Petcherski , Orian Shirihai , David Heber , Zhaoping Li

The OXPHOS supercomplex assembly factor HIG2A responds to changes in energetic metabolism and cell cycle.

Journal of cellular physiology

Avec: Celia Salazar , Alvaro A Elorza , Glenda Cofre , Paula Ruiz-Hincapie , Orian Shirihai , Lina María Ruiz

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.

Nature

Avec: Milica Momcilovic , Anthony Jones , Sean T Bailey , Christopher M Waldmann , Rui Li , Jason T Lee , Gihad Abdelhady , Adrian Gomez , Travis Holloway , Ernst Schmid , David Stout , Michael C Fishbein , Linsey Stiles , Deepa V Dabir , Steven M Dubinett , Heather Christofk , Orian Shirihai , Carla M Koehler , Saman Sadeghi , David B Shackelford

Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas.

Nature communications

Avec: Kun Do Rhee , Yanjie Wang , Johanna Ten Hoeve , Linsey Stiles , Thao Thi Thu Nguyen , Xiangmei Zhang , Laurent Vergnes , Karen Reue , Orian Shirihai , Dean Bok , Xian-Jie Yang

Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria.

Science advances

Avec: Zhenqi Zhou , Alice Ma , Timothy M Moore , Dane M Wolf , Nicole Yang , Peter Tran , Mayuko Segawa , Alexander R Strumwasser , Wenjuan Ren , Kai Fu , Jonathan Wanagat , Alexander M van der Bliek , Rachelle Crosbie-Watson , Marc Liesa , Linsey Stiles , Rebecca Acin-Perez , Sushil Mahata , Orian Shirihai , Mark O Goodarzi , Michal Handzlik , Christian M Metallo , David W Walker , Andrea L Hevener

PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity.

bioRxiv : the preprint server for biology

Avec: Grigor Varuzhanyan , Chia-Chun Chen , Jack Freeland , Tian He , Wendy Tran , Kai Song , Liang Wang , Donghui Cheng , Shili Xu , Gabriella A Dibernardo , Favour N Esedebe , Evan R Abt , Jung Wook Park , Sanaz Memarzadeh , Thomas Graeber , Orian Shirihai , Owen Witte

Dispersion indices for universal quantification of fluorescently-labelled subcellular structure spatial distributions.

bioRxiv : the preprint server for biology

Avec: Andrew Martin , Sue Zhang , Amanda Williamson , Brett Tingley , Mira Pickus , David Zurakowski , Hadi T Nia , Orian Shirihai , Xue Han , Mark W Grinstaff

Estrogen receptor α controls metabolism in white and brown adipocytes by regulating

Science translational medicine

Avec: Zhenqi Zhou , Timothy M Moore , Brian G Drew , Vicent Ribas , Jonathan Wanagat , Mete Civelek , Mayuko Segawa , Dane M Wolf , Frode Norheim , Marcus M Seldin , Alexander R Strumwasser , Kate A Whitney , Ellen Lester , Britany R Reddish , Laurent Vergnes , Karen Reue , Prashant Rajbhandari , Peter Tontonoz , Jason Lee , Sushil K Mahata , Sylvia C Hewitt , Orian Shirihai , Craig Gastonbury , Kerrin S Small , Markku Laakso , Jorgen Jensen , Sindre Lee , Christian A Drevon , Kenneth S Korach , Aldons J Lusis , Andrea L Hevener

DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer.

Communications biology

Avec: Ning Shen , Sovannarith Korm , Theodoros Karantanos , Dun Li , Xiaoyu Zhang , Eleni Ritou , Hanfei Xu , Andrew Lam , Justin English , Wei-Xing Zong , Ching-Ti Liu , Orian Shirihai , Hui Feng

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle.

Molecular metabolism

Avec: Timothy M Moore , Zhenqi Zhou , Whitaker Cohn , Frode Norheim , Amanda J Lin , Nareg Kalajian , Alexander R Strumwasser , Kevin Cory , Kate Whitney , Theodore Ho , Timothy Ho , Joseph L Lee , Daniel H Rucker , Orian Shirihai , Alexander M van der Bliek , Julian P Whitelegge , Marcus M Seldin , Aldons J Lusis , Sindre Lee , Christian A Drevon , Sushil K Mahata , Lorraine P Turcotte , Andrea L Hevener

Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.

Nature

Avec: Milica Momcilovic , Anthony Jones , Sean T Bailey , Christopher M Waldmann , Rui Li , Jason T Lee , Gihad Abdelhady , Adrian Gomez , Travis Holloway , Ernst Schmid , David Stout , Michael C Fishbein , Linsey Stiles , Deepa V Dabir , Steven M Dubinett , Heather Christofk , Orian Shirihai , Carla M Koehler , Saman Sadeghi , David B Shackelford

A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity.

Research square

Avec: Martin Picard , Eugene Mosharov , Ayelet Rosenberg , Anna Monzel , Corey Osto , Linsey Stiles , Gorazd Rosoklija , Andrew Dwork , Snehal Bindra , Ya Zhang , Masashi Fujita , Madeline Mariani , Mihran Bakalian , David Sulzer , Philip De Jager , Vilas Menon , Orian Shirihai , John Mann , Mark Underwood , Maura Boldrini , Michel Thiebaut de Schotten

A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction.

Cell reports. Medicine

Avec: Shen Li , Bo Tao , Jijun Wan , Enca Montecino-Rodriguez , Ping Wang , Feiyang Ma , Baiming Sun , Yiqian Gu , Sivakumar Ramadoss , Lianjiu Su , Qihao Sun , Johanna Ten Hoeve , Linsey Stiles , Jeffrey Collins , R Michael van Dam , Mikayla Tamboline , Richard Taschereau , Orian Shirihai , Douglas B Kitchen , Matteo Pellegrini , Thomas Graeber , Kenneth Dorshkind , Shili Xu , Arjun Deb

Réseau de co-auteurs

Linsey Stiles 6 collaborations

Zhenqi Zhou 3 collaborations

Timothy M Moore 3 collaborations

Alexander R Strumwasser 3 collaborations

Andrea L Hevener 3 collaborations

Milica Momcilovic 2 collaborations

Anthony Jones 2 collaborations

Sean T Bailey 2 collaborations

Christopher M Waldmann 2 collaborations

Rui Li 2 collaborations

Jason T Lee 2 collaborations

Gihad Abdelhady 2 collaborations

Adrian Gomez 2 collaborations

Travis Holloway 2 collaborations

Ernst Schmid 2 collaborations

David Stout 2 collaborations

Michael C Fishbein 2 collaborations

Deepa V Dabir 2 collaborations

Steven M Dubinett 2 collaborations

Heather Christofk 2 collaborations

Carla M Koehler 2 collaborations

Saman Sadeghi 2 collaborations

David B Shackelford 2 collaborations

Johanna Ten Hoeve 2 collaborations

Laurent Vergnes 2 collaborations

Karen Reue 2 collaborations

Dane M Wolf 2 collaborations

Mayuko Segawa 2 collaborations

Jonathan Wanagat 2 collaborations

Alexander M van der Bliek 2 collaborations

Shili Xu 2 collaborations

Thomas Graeber 2 collaborations

Frode Norheim 2 collaborations

Marcus M Seldin 2 collaborations

Sushil K Mahata 2 collaborations

Sindre Lee 2 collaborations

Christian A Drevon 2 collaborations

Aldons J Lusis 2 collaborations

Jieping Yang 1 collaboration

Yuanqiang Guo 1 collaboration

Susanne M Henning 1 collaboration

Brenda Chan 1 collaboration

Jianfeng Long 1 collaboration

Jin Zhong 1 collaboration

Rebeca Acin-Perez 1 collaboration

Anton Petcherski 1 collaboration

David Heber 1 collaboration

Zhaoping Li 1 collaboration

Celia Salazar 1 collaboration

Alvaro A Elorza 1 collaboration

Glenda Cofre 1 collaboration

Paula Ruiz-Hincapie 1 collaboration

Lina María Ruiz 1 collaboration

Kun Do Rhee 1 collaboration

Yanjie Wang 1 collaboration

Thao Thi Thu Nguyen 1 collaboration

Xiangmei Zhang 1 collaboration

Dean Bok 1 collaboration

Xian-Jie Yang 1 collaboration

Alice Ma 1 collaboration

Nicole Yang 1 collaboration

Peter Tran 1 collaboration

Wenjuan Ren 1 collaboration

Kai Fu 1 collaboration

Rachelle Crosbie-Watson 1 collaboration

Marc Liesa 1 collaboration

Rebecca Acin-Perez 1 collaboration

Sushil Mahata 1 collaboration

Mark O Goodarzi 1 collaboration

Michal Handzlik 1 collaboration

Christian M Metallo 1 collaboration

David W Walker 1 collaboration

Grigor Varuzhanyan 1 collaboration

Chia-Chun Chen 1 collaboration

Jack Freeland 1 collaboration

Tian He 1 collaboration

Wendy Tran 1 collaboration

Kai Song 1 collaboration

Liang Wang 1 collaboration

Donghui Cheng 1 collaboration

Gabriella A Dibernardo 1 collaboration

Favour N Esedebe 1 collaboration

Evan R Abt 1 collaboration

Jung Wook Park 1 collaboration

Sanaz Memarzadeh 1 collaboration

Owen Witte 1 collaboration

Andrew Martin 1 collaboration

Sue Zhang 1 collaboration

Amanda Williamson 1 collaboration

Brett Tingley 1 collaboration

Mira Pickus 1 collaboration

David Zurakowski 1 collaboration

Hadi T Nia 1 collaboration

Xue Han 1 collaboration

Mark W Grinstaff 1 collaboration

Brian G Drew 1 collaboration

Vicent Ribas 1 collaboration

Mete Civelek 1 collaboration

Kate A Whitney 1 collaboration

Ellen Lester 1 collaboration

Britany R Reddish 1 collaboration

Prashant Rajbhandari 1 collaboration

Peter Tontonoz 1 collaboration

Jason Lee 1 collaboration

Sylvia C Hewitt 1 collaboration

Craig Gastonbury 1 collaboration

Kerrin S Small 1 collaboration

Markku Laakso 1 collaboration

Jorgen Jensen 1 collaboration

Kenneth S Korach 1 collaboration

Ning Shen 1 collaboration

Sovannarith Korm 1 collaboration

Theodoros Karantanos 1 collaboration

Dun Li 1 collaboration

Xiaoyu Zhang 1 collaboration

Eleni Ritou 1 collaboration

Hanfei Xu 1 collaboration

Andrew Lam 1 collaboration

Justin English 1 collaboration

Wei-Xing Zong 1 collaboration

Ching-Ti Liu 1 collaboration

Hui Feng 1 collaboration

Whitaker Cohn 1 collaboration

Amanda J Lin 1 collaboration

Nareg Kalajian 1 collaboration

Kevin Cory 1 collaboration

Kate Whitney 1 collaboration

Theodore Ho 1 collaboration

Timothy Ho 1 collaboration

Joseph L Lee 1 collaboration

Daniel H Rucker 1 collaboration

Julian P Whitelegge 1 collaboration

Lorraine P Turcotte 1 collaboration

Martin Picard 1 collaboration

Eugene Mosharov 1 collaboration

Ayelet Rosenberg 1 collaboration

Anna Monzel 1 collaboration

Corey Osto 1 collaboration

Gorazd Rosoklija 1 collaboration

Andrew Dwork 1 collaboration

Snehal Bindra 1 collaboration

Ya Zhang 1 collaboration

Masashi Fujita 1 collaboration

Madeline Mariani 1 collaboration

Mihran Bakalian 1 collaboration

David Sulzer 1 collaboration

Philip De Jager 1 collaboration

Vilas Menon 1 collaboration

John Mann 1 collaboration

Mark Underwood 1 collaboration

Maura Boldrini 1 collaboration

Michel Thiebaut de Schotten 1 collaboration

Shen Li 1 collaboration

Bo Tao 1 collaboration

Jijun Wan 1 collaboration

Enca Montecino-Rodriguez 1 collaboration

Ping Wang 1 collaboration

Feiyang Ma 1 collaboration

Baiming Sun 1 collaboration

Yiqian Gu 1 collaboration

Sivakumar Ramadoss 1 collaboration

Lianjiu Su 1 collaboration

Qihao Sun 1 collaboration

Jeffrey Collins 1 collaboration

R Michael van Dam 1 collaboration

Mikayla Tamboline 1 collaboration

Richard Taschereau 1 collaboration

Douglas B Kitchen 1 collaboration

Matteo Pellegrini 1 collaboration

Kenneth Dorshkind 1 collaboration

Arjun Deb 1 collaboration