Nils Brünner

Affiliations

Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark; Scandion Oncology, Denmark.

Publications (10)

Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Asbjørn Nøhr-Nielsen , Sofie Otzen Bagger , Nils Brünner , Jan Stenvang , Trine Meldgaard Lund

A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer.

Frontiers in oncology

Avec: Peide Huang , Fengyu Li , Zongchao Mo , Chunyu Geng , Fang Wen , Chunyan Zhang , Jia Guo , Song Wu , Lin Li , Nils Brünner , Jan Stenvang

ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer.

International journal of molecular sciences

Avec: Jesper Andreas Palshof , Camilla Natasha Cederbye , Estrid Vilma Solyom Høgdall , Tim Svenstrup Poulsen , Dorte Linnemann , Sune Boris Nygaard , Jan Stenvang , Ib Jarle Christensen , Benny Vittrup Jensen , Per Pfeiffer , Nils Brünner , Mette Yilmaz , Birgitte Martine Viuff , Dorte Lisbet Nielsen

Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers.

Basic & clinical pharmacology & toxicology

Avec: Troels K Bergmann , Tore B Stage , Jan Stenvang , Palle Christophersen , Thomas A Jacobsen , Nicklas L Roest , Peter M Vestlev , Nils Brünner

The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.

Molecular oncology

Avec: Mikkel Høeberg , Julie Boertmann Noer , Mette Vixø Vistesen , Annette Bartels , Esben Matzen Bech , Sune Boris Nygård , Ulrik Lademann , Jan Stenvang , Siqi Liu , Anja Thoe Fuglsang , Nils Brünner , José Manuel Afonso Moreira

The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP.

Cells

Avec: Sophie E B Ambjørner , Michael Wiese , Sebastian Christoph Köhler , Joen Svindt , Xamuel Loft Lund , Michael Gajhede , Lasse Saaby , Birger Brodin , Steffen Rump , Henning Weigt , Nils Brünner , Jan Stenvang

Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene.

BMC cancer

Avec: Iben Kümler , Eva Balslev , Jan Stenvang , Nils Brünner , Bent Ejlertsen , Erik Hugger Jakobsen , Dorte Lisbet Nielsen

Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines.

Pathology oncology research : POR

Avec: Charlotte Aaberg-Jessen , Louise Fogh , Mia Dahl Sørensen , Bo Halle , Nils Brünner , Bjarne Winther Kristensen

An Explorative Analysis of

Cancers

Avec: Jan Stenvang , Eva Budinská , Eric van Cutsem , Fred Bosman , Vlad Popovici , Nils Brünner

Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia.

Gastroenterology

Avec: Jacob Mathias Bech , Thilde Terkelsen , Annette Snejbjerg Bartels , Fabian Coscia , Sophia Doll , Siqi Zhao , Zhaojun Zhang , Nils Brünner , Jan Lindebjerg , Gunvor Iben Madsen , Xiangdong Fang , Matthias Mann , José Manuel Afonso Moreira

Réseau de co-auteurs

Jan Stenvang 8 collaborations

Dorte Lisbet Nielsen 2 collaborations

José Manuel Afonso Moreira 2 collaborations

Asbjørn Nøhr-Nielsen 1 collaboration

Sofie Otzen Bagger 1 collaboration

Trine Meldgaard Lund 1 collaboration

Peide Huang 1 collaboration

Fengyu Li 1 collaboration

Zongchao Mo 1 collaboration

Chunyu Geng 1 collaboration

Fang Wen 1 collaboration

Chunyan Zhang 1 collaboration

Jia Guo 1 collaboration

Song Wu 1 collaboration

Lin Li 1 collaboration

Jesper Andreas Palshof 1 collaboration

Camilla Natasha Cederbye 1 collaboration

Estrid Vilma Solyom Høgdall 1 collaboration

Tim Svenstrup Poulsen 1 collaboration

Dorte Linnemann 1 collaboration

Sune Boris Nygaard 1 collaboration

Ib Jarle Christensen 1 collaboration

Benny Vittrup Jensen 1 collaboration

Per Pfeiffer 1 collaboration

Mette Yilmaz 1 collaboration

Birgitte Martine Viuff 1 collaboration

Troels K Bergmann 1 collaboration

Tore B Stage 1 collaboration

Palle Christophersen 1 collaboration

Thomas A Jacobsen 1 collaboration

Nicklas L Roest 1 collaboration

Peter M Vestlev 1 collaboration

Mikkel Høeberg 1 collaboration

Julie Boertmann Noer 1 collaboration

Mette Vixø Vistesen 1 collaboration

Annette Bartels 1 collaboration

Esben Matzen Bech 1 collaboration

Sune Boris Nygård 1 collaboration

Ulrik Lademann 1 collaboration

Siqi Liu 1 collaboration

Anja Thoe Fuglsang 1 collaboration

Sophie E B Ambjørner 1 collaboration

Michael Wiese 1 collaboration

Sebastian Christoph Köhler 1 collaboration

Joen Svindt 1 collaboration

Xamuel Loft Lund 1 collaboration

Michael Gajhede 1 collaboration

Lasse Saaby 1 collaboration

Birger Brodin 1 collaboration

Steffen Rump 1 collaboration

Henning Weigt 1 collaboration

Iben Kümler 1 collaboration

Eva Balslev 1 collaboration

Bent Ejlertsen 1 collaboration

Erik Hugger Jakobsen 1 collaboration

Charlotte Aaberg-Jessen 1 collaboration

Louise Fogh 1 collaboration

Mia Dahl Sørensen 1 collaboration

Bo Halle 1 collaboration

Bjarne Winther Kristensen 1 collaboration

Eva Budinská 1 collaboration

Eric van Cutsem 1 collaboration

Fred Bosman 1 collaboration

Vlad Popovici 1 collaboration

Jacob Mathias Bech 1 collaboration

Thilde Terkelsen 1 collaboration

Annette Snejbjerg Bartels 1 collaboration

Fabian Coscia 1 collaboration

Sophia Doll 1 collaboration

Siqi Zhao 1 collaboration

Zhaojun Zhang 1 collaboration

Jan Lindebjerg 1 collaboration

Gunvor Iben Madsen 1 collaboration

Xiangdong Fang 1 collaboration

Matthias Mann 1 collaboration